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Lisdexamfetamine - New ADHD Amphetamine Coming Soon

Shire created this shit knowing that it has lower abuse potential than the other stimulants so patients/children can have an alternative to the more abusable ones, and that they can take over the entire industry of ADD/ADHD medications. They are like any other business, just looking to make money. They wanted it lower than schedule II just like everyone else. All they did is take dextroamphetamine and added the amino acid l-lysine to the chain. While doing this, they took a good drug and turned it into complete crap. It's metabolized in the body differently and is very slowly released and activated. You can only take them orally, so no snorting, shooting, and whatnot. The abuse potential is most likely somewhere around concerta or just methylphenidate.

TheTwighlight: If you find Adderall shitty, you won't like Dexedrine/dextroamphetamine either. Don't even touch Vyvanse. Adderall/dextroamphetamine completely blow it out of the water. From everything you have mentioned, no amphetamine or stimulant will be enjoyable for you.

Riemann Zeta: "This would have been fantastic had it been C-III. However, as a C-II chemical, it is utterly worthless, as it is just an expensive form of dexamphetamine SR."

It's not dextroamphetamine sustained-release. It is Vyvanse aka lisdexamfetamine dimesylate, which is A LOT less efficient, recreational, euphoric, and abusable than dextroamphetamine SR or dextroamphetamine sulfate. They aren't the same, so you should research up on it before you post a false statement.
 
TheTwighlight said:
Actually, dextroamphetamine is the ONLY upper I like - so go figure I'm upset about the bastardization of this drug.
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You don't like coke? Forget the money and other factors but the euphoria is undoubtedly more clear than any amphetamine.
 
Virtuoso said:
You don't like coke? Forget the money and other factors but the euphoria is undoubtedly more clear than any amphetamine.
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A lot of people ask "what's better coke or speed?"

For me, the answer to that question is it depends. They are both uppers but the highs are so different. I think because the quality of coke that most people get is such shit most people don't know what a real coke high is.

If I have work to do, need to stay up late, want to dance for hours, etc speed cannot be beaten. The high is kind of an "I can do anything I want" feeling.

With quality coke the high is more of a "I'm the king of the world" type of feeling which is great if you are sitting around chilling talking to people or going to a club and chilling at a table in the vip room. For me its much more of a mental high.
 
I hate cocaine. I used to like smoking primo when I was like 16/17, but now I hate every aspect of the coke high. It's not even a high, if you ask me. It's pure paranoia, coupled with the shakes and a nauseous feeling in my stomach. I've done good coke, too. It all has the same effect after my methamphetamine addiction.
To me, d-amp is a mental high, doesn't make me shake and act super-paranoid, either. I just don't want to ever take any upper again without the aid of benzo and opiates on the way down.
 
TheTwighlight said:
Actually, dextroamphetamine is the ONLY upper I like - so go figure I'm upset about the bastardization of this drug.
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Adderall is ~75% of dextroamphetamine salts so I don't see how you could hate it. If you have Adderall XR, crush all the beads into a powder and put the powder in the capsule. Take a higher dose with a spoonful of baking soda before it kicks in and after. I do this and I can enjoy them. If I were to just take the capsules whole with the beads still intact, it hardly has an effect on me. This is probably why you never enjoyed it. I'm prescribed the stuff myself, but I am going to try to switch to Dexedrine because overall it's better and half the price of Adderall XR. I'm talking about the brand name pills too. I think most people would rather have GlaxoSmithKline Dexedrine Spansules over Shire Adderall XR.
 
Adderall is not ~75mg of the good dextro, though. According to Erowid, one 10mg Addy has:

Dextro-amphetamine Saccharate- 2.5 mg;
Dextro-amphetamine Sulfate(USP)- 2.5 mg;
Racemic-amphetamine Aspartate- 2.5 mg;
Racemic-amphetamine Sulfate- 2.5 mg.

Too much levo-amps. I hate twitching. Plus, adderall makes me very paranoid, like meth. Dextro doesn't do that to me. I don't even like Dexadrine, though. I like DextroStat, it's instant release.
 
psychotiKK said:
Shire created this shit knowing that it has lower abuse potential than the other stimulants so patients/children can have an alternative to the more abusable ones, and that they can take over the entire industry of ADD/ADHD medications...


...While doing this, they took a good drug and turned it into complete crap. It's metabolized in the body differently and is very slowly released and activated. You can only take them orally, so no snorting, shooting, and whatnot. The abuse potential is most likely somewhere around concerta or just methylphenidate.
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Sounds perfect (for me), if I can beat the desire to abuse my ADD rx meds.

psychotiKK said:
...less efficient, recreational, euphoric, and abusable than dextroamphetamine SR or dextroamphetamine sulfate.
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Ideal, IMO.
 
I have taken ADD meds. for a long time now. IMO the only real breakthrough would be to have a Schedule III or Sched. IV ADD med.

I THINK the pharm. company tried to sell FDA on making this a schedule III drug and failing to do that, they are launching it anyway (as a Schedule II med.)

The pharm company rolled the dice, and missed the financial home run of getting it approved as a Sched. III. Their back up plan may be to try and "prove" through real patient use that it has less abuse potential than other Sch. II meds. and apply for a different schedule in a few years.
 
ok I've got a bottle of this stuff from my little sister (who freaked on it) ...]

and i gotta say you guyz are being way to pre-judgemental in my oponion. I have gobs of adderall and this shit; while it may not have the "bang!' of adderall gives a nice high. very nice. esp. when combined with adderall.

it also comes in a nice powder that can be snorted. If anything this is probably a secret scheme to get MORE people addicted to shire!
 
qwe said:
could an average joe separate the L-Lysine from the d-amp?
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Lisdexamfetamine.png


It's a simple amide hydrolysis. Crush pill, add excess HCl and heat for 10 minutes, then continue to heat it to drive any left over HCl off. Stir into OJ (not necessary), swallow.

the person above me said:
it also comes in a nice powder that can be snorted.
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Yes you can snort it, but it will not get you high. It needs to be hydrolysed in your gut to be psychoactive. 8)
 
TheTwighlight said:
Adderall is not ~75mg of the good dextro, though. According to Erowid, one 10mg Addy has:

Dextro-amphetamine Saccharate- 2.5 mg;
Dextro-amphetamine Sulfate(USP)- 2.5 mg;
Racemic-amphetamine Aspartate- 2.5 mg;
Racemic-amphetamine Sulfate- 2.5 mg.

Too much levo-amps. I hate twitching. Plus, adderall makes me very paranoid, like meth. Dextro doesn't do that to me. I don't even like Dexadrine, though. I like DextroStat, it's instant release.
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Adderal is 75% dextro!

Dextro-amphetamine Saccharate- 2.5 mg; -2.5mg dextro
Dextro-amphetamine Sulfate(USP)- 2.5 mg; -2.5mg dextro
Racemic-amphetamine Aspartate- 2.5 mg; -1.25mg levo -1.25mg dextro
Racemic-amphetamine Sulfate- 2.5 mg -1.25mg levo -1.25mg dextro

Now add up the amount of dextro and you get 7.5mg, which 75% of 10mg tab.
 
Ok i don't think pills should be snorted ! just to clarify, but for those who do; it comes in nice powder. and even if it doesn't "scientifically" "work" when snorted; its still friggin does . because i did it last nite and didn't sleep (and i used to sleep while high on meth!) soooooo.....

for instance, xanax isn't water soluble but it still snorts fine and eventually works.

but save your nose the trouble.

my main point is that Vyvance is an authentic amphetamine, maybe even a GOOD one from what i've experienced (a bottle) . so go try it out
 
TheTwighlight said:
Adderall is not ~75mg of the good dextro, though. According to Erowid, one 10mg Addy has:

Dextro-amphetamine Saccharate- 2.5 mg;
Dextro-amphetamine Sulfate(USP)- 2.5 mg;
Racemic-amphetamine Aspartate- 2.5 mg;
Racemic-amphetamine Sulfate- 2.5 mg.

Too much levo-amps. I hate twitching. Plus, adderall makes me very paranoid, like meth. Dextro doesn't do that to me. I don't even like Dexadrine, though. I like DextroStat, it's instant release.
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did you forget what racemic means or something? your quote proves you wrong
 
Found on Wikipedia:
In human oral abuse-liability studies, 150 mg Vyvanse produced a "likeability"—euphoric effect—that was determined to be indistinguishable from 200 mg of the Schedule IV drug diethylpropion hydrochloride or 40 mg of dextroamphetamine.
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Lisdexamfetamine should be very recreational to those who find oral amphetamine very recreational. Instead of a 6-8 hour high from 40mg of d-amphetamine, you get a 12-18 hour high from 150mg of lisdexamfetamine... both highs would feel the same.

If they're putting larger doses in each lisdexamfetamine pill and you're paying the same price per pill as you would for Adderall, it works out to be just as good a drug. The only thing Adderall has going for it is that you can take it early enough to fall asleep at a normal hour. But we're talking about recreational stimulant abuse, where most people want to stay awake for days!
 
I'm talking about NOT-FUCKED-WITH pure d-amp. Adderall feels NOTHING AT ALL like pure dex, instant-release or not. If you wanna disagree with that, go ahead, but I'm sure most people will side with me on this. If not, then I'm giving myself a big-ass "fuck me".
 
LivingOnValium said:
Adderal is 75% dextro!

Dextro-amphetamine Saccharate- 2.5 mg; -2.5mg dextro
Dextro-amphetamine Sulfate(USP)- 2.5 mg; -2.5mg dextro
Racemic-amphetamine Aspartate- 2.5 mg; -1.25mg levo -1.25mg dextro
Racemic-amphetamine Sulfate- 2.5 mg -1.25mg levo -1.25mg dextro

Now add up the amount of dextro and you get 7.5mg, which 75% of 10mg tab.
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This excerpt from Wikipedia accounts for the relatively large subjective difference between Adderall and Dexedrine:

"Aspartate, saccharate, and sulfate salts differ pharmacokinetically in the rate at which they are metabolized by the body. For this and other reasons, Adderall's effects are different from pharmaceuticals with dextroamphetamine as an exclusive active ingredient. Contrary to the beliefs that Adderall is three-quarters dextroamphetamine, dextroamphetamine accounts for 72.7% of the amphetamine base in Adderall."
 
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