LD50 2cb

[gymstud]

Can anyone tell me the LD50 2cb
I've looked on-line can't find a str8 answer

 

[mamdbdylan]

what do u mean LD50 2cb?

Those are 2 different drugs entirely

 

[Vader]

There haven't been a lot of toxicity studies, and even if they had been done, my understanding is that LD50 is an outdated measure that isn't used anymore.

 

[greenmeanies]

^Exactly.

Quote from Shulgin himself on the pointlessness of LD50 studies on animals.

http://www.erowid.org/library/books_online/pihkal/pihkal062.shtml

This is one of the last of the experimental compounds within the phenethylamine family on which any animal toxicity studies were performed by me prior to human studies. A mouse injected with 50 mg/Kg (ip) showed considerable twitching and was irritable. Another, at 100 mg/Kg (ip), had overt shaking at 20 minutes, which evolved into persistent hyperactivity that lasted several hours. Yet another, at 125 mg/Kg (ip), lost much of her righting reflex within 15 minutes, entered into convulsions at 50 minutes, and was dead a half hour later. A fourth mouse, at 150 mg/Kg (ip), entered into spontaneous convulsions within 10 minutes, and expired in what looked like an uncomfortable death at 22 minutes following injection. What was learned? That the LD/50 was somewhere between 100 and 125 mg/Kg for the mouse. And an effective dose in man of maybe 2 mg (for an 80 Kg man) is equivalent to 25 ug/Kg. Therefore the index of safety (the therapeutic index, the lethal dose divided by the effective dose) is well over a thousand. I feel that two mice were killed without anything of value having been received in return.

Actually, it is very likely that the damaging, if not lethal, level of DOB in man is a lot lower than this ratio would imply. There was a report of a death of a young lady following the snorting of an amount of DOB so massive, there was the actual recovery of over nine milligrams of the drug from her body tissues in the post-mortem examination. It was said that she and her companion had thought that the drug they were using was MDA and, taking a dosage appropriate for this, effectively overdosed themselves. He survived, following convulsions and an extended period (several weeks) of being in a comatose state. Tragic examples have been reported that involve arterial vascular spasm. But in most overdose cases ascribed to DOB, the identity of the drug has remained unestablished.

 

[gymstud]

what do u mean LD50 2cb?

Those are 2 different drugs entirely

leathal dose 50%

 

[huolesoh]

well on erowid experience vaults i read of a massive overdose of someone who was fucked up and they thought they were railing coke, anyway they did about 300mg i think, they lived, extremely intense trip

then in PiHKAL a report of 100mg, they "picked up the wrong vial", again lived

yeah 2CB is real sweet, i hope it gets as big as MDMA, LSD in the future

 

[plusfourpirate]

dont know what the LD50 is, but i can tell you based on personal experience that its got to be pretty high.

a couple yrs back my friends and i had a lot of it and were using(abusing would prolly be a more accurate word) it at 50mg doses or higher at one time, and repeating several times over the course of the weekend. it got to where we werent even measuring it, just finger dipping throughout the night like molly. ive seen over a G get killed by 3-4 ppl over a weekend with no real ill effects to speak of. sure there was some nausea involved at times, but honestly, less than i would expect from a 30mg dose of 2c-e.

when i first came across it in the early 90's, the crazy mofos that brought it into our scene told us the doses were .1-.2.n retrospect i guess they meant .01-.02...idk they were pretty wild maybe they didnt, heh..
so my friend took a gram and made 10 caps out of it..we were underinformed and stupid not to look up any more info on it and trust in some idiots word, but we all ate a cap, some 2, at the after party that wknd and had a grand ole time out at the park. irresponsible and reckless, yes, but true shit nonetheless.

in one other more recent instance, my roomie at the time had a baggie of it in his nightstand drawer, and the girl who he brought home poured it out and snorted it thinking it was coke. killed 100 plus mg in one snort, and she weighs 110lbs, if that. she def freaked out the first few hrs, but there were really no side effects to speak of minus a case of the giggles and "kaleidescope visuals" as she described it. she was fine once we gave her a benzo and explained to her that she had accidently taken psychedelics, and was not losing her mind. she said it was one of the most visual trips she ever had. she said she thought she had gone partially bling bc she couldnt see anything but the visuals in front of here face it was so intense.. def been there' 2cb is some visual shiz at higher doses.


im not suggesting you try n push the envelop by any means, just trying to say that based on my and my pplz experience you can take double, triple the amount of a regualar dose and we were fine. but we are/were all very experienced with L and other psychs...not something id reccomend you give to just anyone just bc...and lets not forget as always, YMMV.

looking back on it all, it was wasteful more than anything. as a hardhead,my friends and i find 20mg a little low for our tastes..but lemme tell ya- even if youve eaten a ten strip or two at a time in your day- 50mg of good 2c-b will rock your skull NO doubt..and seems to be within the realm of safe dosage. in the spirit of harm reduction, try the regular doses first tho, mang.

happy trails :D