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l-amphetamine salts: Why its still added to pharms

I think the PDR is mistaken. I thought it was l-amphetamine too, but the evidence suggests otherwise:

Bradley
Benzedrine(R) and dexedrine(R) in the treatment of children's behavior disorders
Pediatrics, Jan 1950, 24-37, Vol 5, No. 1
"The psychologic responses of children to benzedrine (racemic, {dl-}, amphetamine) sulfate and its dextro-rotatory isomer (d-amphetamine) known commercially as dexedrine sulfate have been the subject of several communications appearing in the literature since 1937"

Glaser PE, Thomas TC, Joyce BM, Castellanos FX, Gerhardt GA.
Differential effects of amphetamine isomers on dopamine release in the rat striatum and nucleus accumbens core.
Psychopharmacology (Berl). 2005 Mar;178(2-3):250-8.
"Although taken off the market in the early 1970s, benzedrine, the racemic mixture of amphetamine, had been used for the treatment of ADHD"

and the government is in on it too:
http://www.nhtsa.dot.gov/People/injury/research/job185drugs/methamphetamine.htm
"Amphetamine is also a Schedule II controlled substance and is usually supplied as the sulfate salt of the d-isomer (Dexedrine®), or as the racemic mixture (Benzedrine®)."
 
That's the inhalor, not the pill. I see that link, but do a search for l-amphetamine. There seems to be links that say it was both. But an old PDR from the 80s shows it as being l-amphetamine
 
Here are a few vintage Benzedrine ads, all of which indicate that Benzedrine was racemic amphetamine. I have more of these ads if you'd like to see them.

Tablets & elixir
md28724.jpg

Inhaler
md_benzhaler.jpg


md29603.jpg


Physician's order form for plastic benzedrine inhaler
md29602.jpg
 
Last edited:
fastandbulbous said:
No because the ion that is formed from the H+ transfer to the amine function is bound to a copolymer (usually -COOH or -SO3H) so isn't going anywhere. It's dependant upon the amphetamine being transfered from the polymer bound acid function to an ion in solution, like Cl- in the stomach (the difference in pH will effect the speed at which the amphetamine is turned into a soluble salt
Click to expand...
I really hope to find a way to defeat the time release mechanism. I swallowed 15 mg of crushed up XR at 9 am. I couldn't sleep until 6 in the morning. Fucking ridiculous. That's what I hate about meth. Dexedrine is ok for duration. Looks like SWIM will have to stick with methcathinone, which I don't think gets the attention it deserves. It's got some really nice properties. It's just not a good money maker. The only good thing about it, is that it's so easy to make. And maybe that's why nobody likes it. It's a bunch of kitchen chemists making low grade methcathinone. Anybody out there like methcathinone or cathinone?
 
cool popcult adds kisps

now i could see where the inhaler is bad for your teeth, but if youre just popping 10-15mg dex/eod and swallowing it straight away with a lot of water, where does the dental damage come from?
 
Changes in the pH within your mouth, etc cause the dental damage. I think tweaking just makes for a bad environment for healthy teeth, among other things.
 
About the ionization - can't you just dissolve beads in conc HCl solln stir for a while leave it overnight and then neutralize with NaOH in the morning... and evap.

Interesting thread btw, wish i had more to contribute.

Edit: the methcathinone user: i have a friend that is fond of this compound, taking it for long durations and then stopping abruptly causes withdrawl, but the withdrawl is alieviated pretty well with caffiene. Just thought you might like to know this for the day you run out!
 
Didn't know that, although I guess it could still have been the original reason they came up with that odd mixture of isomers.
 
Jamshyd said:
Thanks a lot for the informative post, Pdx.

However, I do not see how any of the posts here are realated to what kisps is talking about. The chemistry of Adderal and Dexedrine is irrelevent - what is relevent is that they are both available to doctors and that doctors can perscribe any of them without difficulty.

Case in point: Canada. We only have Dexedrine. There is no Adderal (as far as I know).
Click to expand...

Adderal was legalized again in Canada.
 
Dexostat has a phenobarb type component, vs. Dexedrine. Obetrol, first marketed, was 25% methamphetamine. Air Force still supplies dex for long flights, and ativan to sleep at end of shift.
 
Morb said:
cool popcult adds kisps

now i could see where the inhaler is bad for your teeth, but if youre just popping 10-15mg dex/eod and swallowing it straight away with a lot of water, where does the dental damage come from?
Click to expand...

Reduced saliva production, teeth grinding & poor dental hygene (as seen with heavy use - too fucked up to think about brushing teeth!)
 
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