Bupe Kratom works on subs ?

[Pill Clinton]

Worked for me.

 

[thebigd^]

It is likely that the non-opioid portion of the kratom effects would still be felt, though it is subtle at best, when on bupe. It will not cause PWD though, bupe causes PWD when you're addicted to something else and take it. If you take something on top of bupe, it can't cause PWD, it will just not work at all, or only work a tiny bit.

And actually, if you're addicted to kratom and take bupe, it also won't cause PWD like it does with other opioids. This is, I believe, because kratom and bupe are both partial agonists. So the bupe indeed kicks the kratom alkaloids out of the receptors, but since bupe and kratom are both partial agonists, it will fully substitute for the kratom and you won't get sick (in fact I prefer bupe's high to kratom's)

Old thread but ty. tl;dr Was hit by a car at 28, 34 now with a TBI, one eye, metal everywhere. Was taking kratom for years, doc got me on once daily 16mg subs in the morning, wanted to add in some energy with some kanna so this answer allowed me to dose a small amount of gmd - ty.

 

[Keif' Richards]

Thus may have already been covered, so forgive me.

Kratom's constituent/pharmacological active chemicals are known as Mitragynine(s). Most evidence points squarely at Opioid agonist properties.

There could be some lesser-know qualities as Kratom is not as well-understpod as say, Opium. However, it seems like a safe disposition to treat Kratom as a member of the mild Opioids like Codeine or perhaps Tramadol. The potency varies, though thus is a good place to start.

 

[Keif' Richards]

Thus may have already been covered, so forgive me.

Kratom's constituent/pharmacological active chemicals are known as Mitragynine(s). Most evidence points squarely at Opioid agonist properties.

There could be some lesser-know qualities as Kratom is not as well-understpod as say, Opium. However, it seems like a safe disposition to treat Kratom as a member of the mild Opioids like Codeine or perhaps Tramadol. The potency varies, though thus is a good place to stary

 

[PharmaTrain]

The most common active alkaloid in kratom is Mitragynine, it's a partial agonist of the μ-opioid receptors and a competitive antagonist of the δ-opioid receptors and also have some affinity as an antagonist for the k-opioid receptors.
Buprenorphine is a partial Agonist with very high affinity for the μ-opioid receptors and a high affinity antagonist for the δ-opioid receptors and k-opioid receptors.
That being said, in my younger days I would sometimes ignore my better instincts and mix and match substances without much care. With this particular combination, for me personally, I always felt like the Kratom doses noticeably potentiated my buprenorphine. (By the way I would usually take 8 mg of Buprenorphine with 10-20 10x Kratom capsules) This is a pretty steep dose of either chemical for most people and I in no way condone or advise my youthful indiscretions. And to answer the end of the original poster's question, No, in my experience, mitragyna speciosa never sent me into any sort of precipitated withdrawal if I took it before my suboxone. Kratom and Buprenorphine always seemed to compliment one another as opposed to a traditional opiate mixed Buprenorphine.
-Note: These are all my personal recollections and I don't ever advise anyone to abuse drugs or to use drugs unless absolutely necessary. Some of us need drugs to get by and if anybody can avoid becoming like me, then I certainly advise that they do so because this is a rough life.

Can you use Kratom to come off bupe?

 

[Juicewrldfan]

Ime somewhat but I also barely feel kratom normally so take that for what it’s worth.

I have not had the same experience with methadone even at 25ml I’m at now cuz I’m tapering off

 

[PharmaTrain]

Ime somewhat but I also barely feel kratom normally so take that for what it’s worth.

I have not had the same experience with methadone even at 25ml I’m at now cuz I’m tapering off

Thanks for the feedback. I honestly think it's easier to come of methadone than bupe.