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Kratom Kratom and MAOIs

I'm not 100% sure but I would assume that some of the alkaloids do interact, and probably negatively. It's not something that I would risk.
 
I don't think its been studied, but some kratom alkaloids do have a serotonergic effect so I'd be cautious with MAOIs and anything else like it.

Anecdotally, I can say that taking other serotonergics like 5htp with kratom can be quite dysphoric, but ultimately proved safe.
 
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