General alcazar Bluelighter Joined Jan 15, 2007 Messages 391 Location South American Jungle Jul 11, 2025 #1 Do MAOIs like harmaline interact with kratom alkaloids. I can’t seem to find anything definitive. Only harmaline being used to help with withdrawals.
Do MAOIs like harmaline interact with kratom alkaloids. I can’t seem to find anything definitive. Only harmaline being used to help with withdrawals.
SuperPsych Bluelighter Joined Apr 29, 2012 Messages 1,057 Jul 12, 2025 #2 I'm not 100% sure but I would assume that some of the alkaloids do interact, and probably negatively. It's not something that I would risk.
I'm not 100% sure but I would assume that some of the alkaloids do interact, and probably negatively. It's not something that I would risk.
SotPoker1012 Bluelighter Joined Feb 12, 2025 Messages 315 Jul 12, 2025 #3 I don't think its been studied, but some kratom alkaloids do have a serotonergic effect so I'd be cautious with MAOIs and anything else like it. Anecdotally, I can say that taking other serotonergics like 5htp with kratom can be quite dysphoric, but ultimately proved safe.
I don't think its been studied, but some kratom alkaloids do have a serotonergic effect so I'd be cautious with MAOIs and anything else like it. Anecdotally, I can say that taking other serotonergics like 5htp with kratom can be quite dysphoric, but ultimately proved safe.