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Ketamine

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ketakid

Ex-Bluelighter
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Will saturating Ketamine hcl (not liquid solution) and cooking in it in order to get a dryer product result in any loss of potency?

what high temps can ketamine withstand without damage?

the goal here is to have a less clumpy end product while maintaining potency
 
"Will saturating Ketamine hcl (not liquid solution) and cooking in it in"
Not quite sure what you mean by this.

It melts at 266 degrees centigrade as the hydrochloride salt.
 
I meant will adding the HCL to water and cooking it to get a dryer product result in potency loss.. if the HCL to begin with had some undesired moisture/ clumpyness

Is it true that after cooked into powder, ketamine has a short lifespan? meaning it degrades quicker...meaning ineffective storage
 
MattPsy It melts at 266 degrees centigrade as the hydrochloride salt.[/QUOTE said:
i mean when in water and cooking in an oven what temp. can cause loss of potency
 
Well, the reference I read didn't state the decomposition temperature. Since it didn't mention it but did mention the MP of ketamine, i'd say anything up to that value (~260 degrees) would be okay.

Just boil the water off - that's 100 degrees centigrade. Well within the "OK" range.

And no, without decomposition or isomerization (which to my knowledge does not occur during "cooking") then no change in potency will occur.

I'm not sure about the atmospheric stabillity of Ketamine in regards to degradation of any kind for sure, but I can see no structural features in the Ketamine molecule that would leave it open to this sort of degradation. It's pretty stable stuff, IIRC.
 
Decant Ketamine vial contents onto a rectangular shaped Pyrex casserole dish. Let stand until evaporation is complete. Scrape up crystals with razor blade. Yield is approximately 1.2g per Ketaset vial (10mg/mL).
 
ketakid said:
I meant will adding the HCL to water and cooking it to get a dryer product result in potency loss.. if the HCL to begin with had some undesired moisture/ clumpyness

You should get very little or no potency loss at all, depending how you cook it. Also, don't use too much water as Ketamine is quite soluble in water and will take ages to evapourate if the concentration is low.

Is it true that after cooked into powder, ketamine has a short lifespan? meaning it degrades quicker...meaning ineffective storage

No.
 
^ Thankyou... due to trials, I have gleamed the info that ketamine can be
re-saturated & re-cooked multiple times in order to manipulate appearence and texture, with no potency loss.. in fact, better texture has lead to better absorbtion which equaled better product.....=D

however a slight loss in final weight was observed.... i think it was about 30 miligrams on the gram that was lost....hmmm
 
place K on plate over simmering pan allow steam to heat bottom of plate move with blade as drying.

K will loose potency over time once cooked! its best to cook up 20mls at a time = 1 g though be aware if you get through more than a g (with tolerance it can take several g's for a nights session) cooking afterwards can be risky!
 
ketakid said:
and how long will it hold b4 degrading once cooked

thats difficult to say, much would depend on storage, in a swaety pocket a lot less than a dry space. I know from experience that K is less potent after even a week and we always used to use on the night- but mabye we were greedy=D
 
Can I get a second opinion to the shelf life of ketamine hcl....

i want to know if it will retain potency a month from now if need be.
 
ketamine shelf-life

From experience ketamine HCL (liquid) is much more potent hot off the plate or pyrex for some of you.
 
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