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Ketamine Ketamine usage
- Thread starter bbsjjb
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placebonaut
Bluelighter
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- Feb 7, 2026
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Hopefully you're already aware that Ket can cause bladder damage, there are a number of studies out there worth looking up, I'm going from memory here, but IIRC the conclusion was that using ket 9 times a month is linked to a much higher risk of bladder damage. Not sure at what amounts but 1g is quite a lot of ket to be getting through in 1 day let alone 11g in a week...
Yeah you should probably be concerned. I'm not K expert by any means but I loved me some MXE. You should consider quitting for awhile I think. K can cause terrible bladder damage and you don't want to end up like those guys trust me. Are you even managing to reach the K-hole anymore?
I M-holed a lot when I had a nice stash of MXE around. Setting possible bladder damage aside consider this: Going into the hole and using dissos everyday is a really bad idea in general. They really should be kept to a once and awhile type of thing. They are highly addictive and when you're bingeing on them everyday you don't realize how detached from reality you're getting even if you think you're down and sober. MXE caused a lot of mania in me and I'm not someone prone to it. By the end of I was convinced of things like:
- I'm going to jump on this coal train and ride it North to a major rail depot. Then I'm going to start marching towards Washing D.C. There I will give a speech on the street and I'm going to talk to everyone I meet along the way and try to convince them to march with me. Once everyone hears what I have to say and I have the hundreds of supporters I'll meet along the way and in D.C. it will inspire everyone that sees it on TV to join me. Then we can finally have world peace! We even walked up to meet the train and everything before my thankfully less manic friends I was sharing the MXE with said they wanted to walk back to the house and chill. Which I thought was fine since I could always hop on the train tomorrow with or without them.
I've had K to of course. The doses are higher but it's the same thing as long term MXE use with this whole delusions/mania thing and feeling detached thing. It's just a part of any daily use of a disso.
Lay off awhile and see how you feel in a week. I bet you'll feel much better. Even if you really love it and don't want to stop it isn't worth the possible bladder damage. Never mind the whole hole losing the novelty and tolerance problems.
I M-holed a lot when I had a nice stash of MXE around. Setting possible bladder damage aside consider this: Going into the hole and using dissos everyday is a really bad idea in general. They really should be kept to a once and awhile type of thing. They are highly addictive and when you're bingeing on them everyday you don't realize how detached from reality you're getting even if you think you're down and sober. MXE caused a lot of mania in me and I'm not someone prone to it. By the end of I was convinced of things like:
- I'm going to jump on this coal train and ride it North to a major rail depot. Then I'm going to start marching towards Washing D.C. There I will give a speech on the street and I'm going to talk to everyone I meet along the way and try to convince them to march with me. Once everyone hears what I have to say and I have the hundreds of supporters I'll meet along the way and in D.C. it will inspire everyone that sees it on TV to join me. Then we can finally have world peace! We even walked up to meet the train and everything before my thankfully less manic friends I was sharing the MXE with said they wanted to walk back to the house and chill. Which I thought was fine since I could always hop on the train tomorrow with or without them.
I've had K to of course. The doses are higher but it's the same thing as long term MXE use with this whole delusions/mania thing and feeling detached thing. It's just a part of any daily use of a disso.
Lay off awhile and see how you feel in a week. I bet you'll feel much better. Even if you really love it and don't want to stop it isn't worth the possible bladder damage. Never mind the whole hole losing the novelty and tolerance problems.
Deleted member 593549
Bluelighter
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- Nov 21, 2025
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- 462
ketamine destroyed my life by giving be bladder cystitis
i used to get cramps, they would resolve after a day or two. this was permanent damage being done not my body healing and being ready for more ketamine.
i’m seeing increased reports of ppl getting bladder cystitis from clinical ketamine treatment which is very minimal use.
some ppl are more sensitive to the damage than others. it’s believed to active inflammatory and immune responses that destroy the bladder GAG layer then the tissue. the gag layer does not regenerate, you’re slowly chipping away at it.
i would recommend an IV crack and fentanyl addiction over a ketamine addiction.
there’s a sticky thread in psychedelics subforum that cites a bunch of scientific papers about how ketamine destroys the bladder liver and bile ducts
this is the most dangerous drugs in existence imo.
trust me death from fentanyl OD is better than bladder cystitis and you’re gonna be on fentanyl permanently anyways when your bladder feels like it has a molten knife in it permanently for the rest of your life.
i used to get cramps, they would resolve after a day or two. this was permanent damage being done not my body healing and being ready for more ketamine.
i’m seeing increased reports of ppl getting bladder cystitis from clinical ketamine treatment which is very minimal use.
some ppl are more sensitive to the damage than others. it’s believed to active inflammatory and immune responses that destroy the bladder GAG layer then the tissue. the gag layer does not regenerate, you’re slowly chipping away at it.
i would recommend an IV crack and fentanyl addiction over a ketamine addiction.
there’s a sticky thread in psychedelics subforum that cites a bunch of scientific papers about how ketamine destroys the bladder liver and bile ducts
this is the most dangerous drugs in existence imo.
trust me death from fentanyl OD is better than bladder cystitis and you’re gonna be on fentanyl permanently anyways when your bladder feels like it has a molten knife in it permanently for the rest of your life.
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