• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

Ketamine salts solubility

Status
Not open for further replies.
1-phenyl-2-methylamino-3,3,3-trifluoropropane.png


FLOTSAM
1-phenyl-2-methylamino-3,3,3-trifluoropropane

1-(4-methoxyphenyl)-2-methylamino-3,3,3-trifluoropropane.png


JETSAM
1-(4-methoxyphenyl)-2-methylamino-3,3,3-trifluoropropane

1-(2,4,6-trioxo-3,5-diazacyclohexyl)-2-aminopropane.png


INNIE
1-(2,4,6-trioxo-3,5-diazacyclohexyl)-2-aminopropane

1-(2-aminopropyl)-2,4,6-trioxo-3,5-diaza-3,5-dimethylcyclohexane.png


AUDI
1-(2-aminopropyl)-2,4,6-trioxo-3,5-diaza-3,5-dimethylcyclohexane

5-(1methylpiperazin-4-yl)-1,3-diazaindan.png


ANTI-MANIC
5-(1methylpiperazin-4-yl)-1,3-diazaindan
 
Last edited:
1-(piperazin-1-yl)-1-carbomethoxy-1-(4-methylphenyl)methane.png


EDWARD
1-(piperazin-1-yl)-1-carbomethoxy-1-(4-methylphenyl)methane

N-(2-phenyl-1-methylethyl)-1-(piperidine-4-yl)-1-carbomethoxy-1-(4-methylphenyl)oxymethane.png


JONATHAN
N-(2-phenyl-1-methylethyl)-1-(piperidine-4-yl)-1-carbomethoxy-1-(4-methylphenyl)oxymethane
 
Last edited:
Dresden is one of my old usernames. Fluff was a kind of high quality LSD. A molecule is a collection of atoms attached to each other via overlap of orbital electrons.

4-ethylamino-1,1-diphenyl-2-oxapentane.png


FROSTY_FLURRY
4-ethylamino-1,1-diphenyl-2-oxapentane

4-methylamino-1,1-diphenyl-2-oxa-3-oxopentane.png


TASTY_WORLD
4-methylamino-1,1-diphenyl-2-oxa-3-oxopentane

2-methylamino-2-carbophenoxyethane.png


ICEY-ICE
2-methylamino-2-carbophenoxyethane

2-amino-2-carbophenoxyethane.png


OCKHAM'S_RAZOR
2-amino-2-carbophenoxyethane

2-ethylamino-2-carbophenoxyethane.png


NIKKI
2-ethylamino-2-carbophenoxyethane

Danke!

1-(3-hydroxyphenyl)-1-oxa-2-oxo-3-methyl-4-dimethylaminobutane.png


OP8
1-(3-hydroxyphenyl)-1-oxa-2-oxo-3-methyl-4-dimethylaminobutane

Et tu, OP?
 
Last edited:
1-hydroxy-3-carboethoxypropane.png


JUICY_FRUIT
1-hydroxy-3-carboethoxypropane;
HO-CH2CH2CH2-(C=O)-O-CH2CH3

liquid inebriant

1-phenyl-1-oxa-3-aminobutane.png


LOGICAL_PROGRESSION
1-phenyl-1-oxa-3-aminobutane

1-phenyl-1-oxa-3-(methylamino)butane.png


HERCULES
1-phenyl-1-oxa-3-(methylamino)butane
 
Last edited:
specialrelativity said:
What is Dresden? What is fluff? What is molecule?
Mark
Click to expand...

Oh, don't bother. Many of the compounds on this thread are impossible to make, many more are in practice impossible to make and about 98% of what is left would be toxic or inactive. I guess either amphetamine addicts or dick-sizers are posting scaffolds.

If you REALLY want to know what works, Google Patents & various online databases will show you scaffolds and related patents and papers.

I don't think drug design is that complex, but you need to know some basic stuff like Lipinski's Rules of 5 - their are online calculators and if a compound violated a rule, it's almost certainly inactive. As a test, just try inputting some of the stuff posted here. It will instantly discard them. RO5 isn't a methodology of a design, but a really useful way of checking the 'druglikeness' of a compound.

https://pubchem.ncbi.nlm.nih.gov

Just enter the SMILES of a structure in the link above and you will quickly see how MOST of the compounds on this thread violate a rule or are already known... and you do not get to name a compound someone else found.

Of course, if you do find something with the appropriate RO5 that is novel and facile, people WILL tell you. But just drawing random stuff will not work except under the 'million monkeys with a million typewriters' discum.
 
Novel? There Is Nothing New Under The Sun.
Facile? That Is A Relatively Relative Term.
Arguing? Not My Thing, But I Still L.O.V.E You!

I Get My Rocks Off Mentally By Doing This, You Dig? Look At It As Post-Y2K Nuclear Conflagration Modern Art. That's Pretty Much All What A Lot Of It Is.
 
6-acetyl-1,1,2,4,4,7-hexamethyltetralin.png


HONEYSUCKLE
6-acetyl-1,1,2,4,4,7-hexamethyltetralin

Sweetest Smell I've Found Yet!

Simple-ist Inspiration:

1-(6-acetyl-1,1,4,4,7-pentamethyltetralin-2-yl)-2-aminoethane.png


NUT_SACK
1-(6-acetyl-1,1,4,4,7-pentamethyltetralin-2-yl)-2-aminoethane

1-(6-acetyl-1,1,4,4,7-pentamethyltetralin-2-yl)-2-aminopropane.png


HEDGING_MY_BET
1-(6-acetyl-1,1,4,4,7-pentamethyltetralin-2-yl)-2-aminopropane

N-allyl-1-(6-acetyl-1,1,4,4,7-pentamethyltetralin-2-yl)-2-amino-1-methoxypropane.png


THE_LONG_SHOT
N-allyl-1-(6-acetyl-1,1,4,4,7-pentamethyltetralin-2-yl)-2-amino-1-methoxypropane

1-(4-acetyl-3-methylphenyl)-2-aminopropane.png


THE_MONEY_SHOT
1-(4-acetyl-3-methylphenyl)-2-aminopropane

4-oxa-2-amino-6-acetyl-1,3,3,7-tetramethyltetralin.png


EVEN_FURTHER_OUT
4-oxa-2-amino-6-acetyl-1,3,3,7-tetramethyltetralin
 
Last edited:
1-(3,4,5-trimethoxyphenyl)-1-(4-piperidinyl)methane.png


BEAVIS
1-(3,4,5-trimethoxyphenyl)-1-(4-piperidinyl)methane

1-(3,4-methylenedioxy-5-methoxyphenyl)-1-(4-piperidinyl)methane.png


BUTT_HEAD
1-(3,4-methylenedioxy-5-methoxyphenyl)-1-(4-piperidinyl)methane

1-(3,4-methylenedioxyphenyl)-1-(4-piperidinyl)methane.png


DARIA
1-(3,4-methylenedioxyphenyl)-1-(4-piperidinyl)methane

1-phenyl-1-(4-piperidinyl)methane.png


LIL_BOBBY
1-phenyl-1-(4-piperidinyl)methane

You Know, Lil Bobby's A Genius.
 
Last edited:
Join Us! Hammilton Did. And Now He Holds The Patent For Over 200 Tryptamines.

"Excuse Me, I Am A Monkey."--Aromaticity (me) @ The HIve, last century.
 
I note that JSMOL is an open-source 3D viewer for organic chemicals. Given that it's written in Java, is it possible to add to Bluelight as viewing in 3D is of great value - especially if one is able to calculate minimum-energy conformation and overly 2 or more scaffolds.

I've also noted that https://app.syntelly.com/smiles2iupac is another online resource that converts a SMILES string into IUPAC naming.

If the 2 packages above could be included within BL it would have the potential to add a lot of new data while reducing the size of the database.
 
1-(4-acetylindole-3-yl)-2-dimethylaminoethane.png


SWEET_CAROLINE
1-(4-acetylindole-3-yl)-2-dimethylaminoethane

1-(5-acetylindole-3-yl)-2-dimethylaminoethane.png


SASHA_ALEXANDER_SHULGIN
1-(5-acetylindole-3-yl)-2-dimethylaminoethane

Sassy!

1-(4-acetylphenyl)-2-aminopropane.png


SAINT_PETER_SCHMID
1-(4-acetylphenyl)-2-aminopropane

Meine brudder. It might dimerize a bit. Shouldn't be too bad, though.
 
Last edited:
Well it's the promethazine (antihistamine) molecule with a a 2-ethyl-2,3-dihydro-1H-isoindole moiety stuck to the 3 position.

I guess it's best to do is:

1- go to Wikipedia page on promethazine
2- copy the SMILES string of promethazine from the Wiki page
3- go to the Pubchem site
4- Paste in the promethazine SMILES and look at 'substructures'

That should only take a minute to do and maybe 10 more to find the compound if it's been made.

That way you will be able to see how people have added to the promethazine scaffold and what the results were. Pubmed is an awesome free resource.
 
1-(3,5-dimethoxy-4-acetylphenyl)-2-aminopropane.png


MARY ANN
1-(3,5-dimethoxy-4-acetylphenyl)-2-aminopropane

1-(3-methoxy-4-acetylphenyl)-2-ethylaminopropane.png


GINGER
1-(3-methoxy-4-acetylphenyl)-2-ethylaminopropane

1-(3-acetylphenyl)-2-aminopropane.png


GILLIGAN
1-(3-acetylphenyl)-2-aminopropane
 
Last edited:
Status
Not open for further replies.
Top