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Misc Ketamine - instant anti-depressant

I

Ismene2

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Oct 29, 2018
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Anyone struggling with depression - try 10mg of K under your tongue. Hold for 3-4 mins then spit it out. Within 20 mins you should feel ok.

If not, write your opinion on a Beatle wig and send it to someone who gives a damn :love:
 
Why do you spit it out? Is it caustic? I do like doing small bumps of ket o-K-sionally (pff) to relax, as much as I like doing larger amounts. How long do you find this antidepressant effect lasts? I may have to get a small amount and suck it and see.
 
Not too caustic, damn sure doesn’t taste good though. I too am curious on why spitting out? I’ve heard the same with buprenorphine.

-GC
 
www.nih.gov

Medication Quickly Lifts Bipolar Depression Symptoms

People with treatment-resistant bipolar disorder were relieved from depression symptoms in as little as 40 minutes after an intravenous dose of ketamine. Researchers are now focusing on similar compounds suitable for clinical use.
www.nih.gov www.nih.gov

Well, yes. The rapid, anti-depressant effects of Ketamine are pretty well known at this point.
 
If you swallow it it lasts forever and you cant sleep. Only started doing it last night and tonight - feeling great so far. (As the man who jumped off the empire state said halfway down)
 
I find an approx 30mg 'line' will provide noticeable mood lift for up to a week. Wouldn't be having it within, say, 4 hours of wanting to sleep though

I get the same value/length moodlift from a more recreational evening on it too though...maybe say 3 x 70mg lines spaced 90 minutes or so between lines, thank kinda dosing. I know that's pretty small doses for a lot pf people but Ket just isn;t my thing, I'm a 2 or 3 times a yearr indulger...4 at most
 
ageingpartyfiend said:
I find an approx 30mg 'line' will provide noticeable mood lift for up to a week. Wouldn't be having it within, say, 4 hours of wanting to sleep though

I get the same value/length moodlift from a more recreational evening on it too though...maybe say 3 x 70mg lines spaced 90 minutes or so between lines, thank kinda dosing. I know that's pretty small doses for a lot pf people but Ket just isn;t my thing, I'm a 2 or 3 times a yearr indulger...4 at most
Click to expand...

Interesting - in the K for depression book it says the effect from big doses isn't always as effective as the low dose under the tongue. I suppose the feeling of your mind lifting away from your body can disturb some!
 
Ismene2 said:
Interesting - in the K for depression book it says the effect from big doses isn't always as effective as the low dose under the tongue. I suppose the feeling of your mind lifting away from your body can disturb some!
Click to expand...
also interesting is that (I'm almost certain anyway) they use high k-hole type doses specifically for depression treatment in the ket clinics in the US
 
Theres some intravenous treatments that must be big dose too - I dont think they give em enough to trip tho? (im still reading about it)
 
Ismene2 said:
Theres some intravenous treatments that must be big dose too - I dont think they give em enough to trip tho? (im still reading about it)
Click to expand...
Ya neva tried mxe?

Dmxe is ok but not on the same level as mxe or ketamine.
 
Ismene2 said:
Theres some intravenous treatments that must be big dose too - I dont think they give em enough to trip tho? (im still reading about it)
Click to expand...
often they are too big to trip on, apparently you just get knocked out and wake if they want you under for some reason. I have tried to make sense of it and I've understood commonly you just wake up later when trip is over, might be also the other drugs prolonging anesthesia. But I've heard high dose IV can lead to that also in recreational setup.
 
I made the same experience with good old methoxetamine and deschloroketamine but my required dosages were a bit higher, maybe 10mg MXE sublingually or intranasally. Rapid-onset antidepressant effect, yet I developed tolerance upon using higher trip dosages and then the effect ceased to be sustained, just acutely antidepressant for a few hours to a day.
 
The sub luingal dose is supposed to be 10mg but even the tiniest dose works for me - literally 2 or 3 tiny shards barely visible has a big effect.
 
Arnold said:
Ya neva tried mxe?

Dmxe is ok but not on the same level as mxe or ketamine.
Click to expand...

Think I tried a bit years ago and I used to take K a bit too but never noticed the anti-depressant effect as much as I have this time.
 
In my body k doesn't work like an antidepressant . I have to say that I only took 2 grams in my life. I tried IVed that it was a hard experience and snorted that is more light to go on. But I never feel any weelbeing in that experiences. I will give a try and do it sublingual and a little dose IVed.

Lots of ❤️ and happinnes to all people who is battling with depression. That is a very heavy disease.

💯🥑🥕🧄🦐🐟🥥🥜🌰🥚🍣🍫🧉🍶🧋🌞🔥🏝🕌🗽🌄🚍🚲✈🛫🛩🌈💧🎾🏀🏐🏈🏓🥊🥋🤿🎣🎨🎼🎵🎶🎙🎺🎛🎤🪕🎷🎺🎸🪗🎻🥁🪘💽💿💰🛠🪚⛓️🪝⚙️🗜🧰⚖️💉💊🗿nothing⛔️☯️♋️♀️♂️⚧️
 
I never noticed it from trippy doses - some research shows lower doses work a lot better.
 
amnesiaseizure said:
Maybe don’t write it off when you’ve only ever had 2 grams - and IV’ing the stuff IS pretty full on. IM is a better way to go if you can vouch for purity and sterility. And yeah, real ongoing depression is a fucking nightmare and a killer of many a person out there.
Click to expand...
Why IM is better than IV? I tried one time IM and I felt nothing...I think you have to go with a big dose. I prefer IVing drugs but It's my way to go with drugs. I'd like to buy ket as soon as possible cause I want to experiment with this shit. I have to move 100km to have It. It's the reason why I can't buy easily.
Well have a nice day!
Lots of 💜💜
 
Just to reiterate - this tiny sub-luingal dose under the tongue of K is fucking incredible. If you've ever had that feeling of waking up in the early hours worried sick - K bullfucks that feeling (up the arse) and kicks it out the door.
 
Not a patch on methoxetamine. I was doing a literature for a pharma company, before my wife died. Up to that point, I found a load of papers that reported mxe as having instant action, but longer and more pronounced than ketamine (weirdly, the R isomer is the more effective one).
Yes, I know, any excuse to big up mxe, but it's almost like a member of my family!
 
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