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Just HOW damaging are piperazines?

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Pans-Advocate said:
Who cares? They're so unpleasant that it really shouldn't be a relevant question.
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Not to everyone, some like them.
I hate the fact that they've ruined the MDMA scene, and many times in my n00b days I've purches them hoping/expecting MDMA.

But when I knowingly want to take pipes, I know it releases your serotonin, I'm curious of what type of safety precautions should be taken when dealing with bzp/thpp/mcpp
 
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