Sorry no one has replied to you! I have been off BL and only checking it infrequently.
As to your question, yes you’d be better to use the smallest possible filter which is the 0.22 i think. If you wanted to filter it through the 0.45 first that would be good but it’s going to be a bit of a mission. Worth it though in order to ensure you’re filtering out as many fillers as you can!
I advise not to IV the pill, it’s 60% bioavailable orally, IV it’s something like 78%. Is it worth that extra 18%? Doubtful, it metabolises so quickly when you IV. You are better taking it orally.
Sorry again for the delay, I’ll check tomorrow in case you’ve replied.