This question is a fast one so... Why is it bad to inject a tablet containing paracetamol (and opiate)? I read an article about how there is an injectable formulation for paracetamol. The IV dose is not significantly less than the oral dose, so damage to the liver shouldn't be the reason. Most of the paracetamol is filtered out anyway especially when you use a micron filter (unless you boil your pill) because it is not very soluble in cold water. The paracetamol that does dissolve shouldn't pose any risk due to the low dose, the lack of solid particles, an the fact that it is used (with a different formulation to make I more soluble) in hospitals. That leaves the binders since there is a larger amount of binder needed for a bigger pill. Is that the reason? Because based on everything I know, if you micron filter your tablets it should not be dangerous at all (as safe as illicit iv drug use gets). I'm not asking because I want to try injecting percocet or vicodin (can't get those anyway, I'm in Australia), I'm just curious.
