Opioids IV Morphine vs IV Oxycodone

[benzos4breakfast]

Which do u think gives the best euphoria?

I'm also interested the pros & cons of both. The only info I know is that oxy is more recreational taken orally because of higher BA that's why I wanted to compare them both IV. To see which is better when both having the same BA. Ive always heard that morphine is more sedative. i might have heard somewhere it make ya itch more too.
Im more interested in which gives u the best "rush" after IV. But feel free to say u like it's longer duration, less w/d, better pain killing properties etc. just make sure when u make a choice u write why u like it better.

Anyways, I think morphine's better. Ive only had it twice but it seemed more relaxing. I was maxed out of it on an IV in the hospital once & I also bought a few pills of this guy too another time,
Ive had ALOT more experience with oxy. lost count of how many times. Ive taken doses up to 160mg & also mixed it with benzos. I find it makes me more talkative & not as settled as i was on morphine. I Ived the oxy a few times too so I have experience there too. I'm quitting taking oxy now anyway. Ive been taking it about once a month occasionally twice for the last 6 months & I think the high is overrated for the cost. I dont understand how ppl get addicted to it honestly. At the dose id need to be fully content Id have to take a dose high enough it would later make me throw up. Well if the oxy was cheap than I suppose ya could get addicted to it but where I live it's way to dear.

Off topic but I like the small 5 min peak of taking 600mg of codeine better than 40mg of oxy. oxy is stronger but codeine has a better feel. I suppose the effects of codeine to morphine are closer than the effects of morphine to oxy only comparing the feel of the drugs. not the strength.

 

[80mg]

Uhm...I'd have to go with the Oxycodone. Although Morphine is nice I get more of a rush with the oxy plus it's easier to "cook" up (although you shouldn't really cook it). I'm pretty sure your going to hear this alot.

As for the codiene. Codeine has a ceiling affect of about 430mg. Anything mroe than that is a waste. But honestly your better off with the oxy even if it did go to 600mg.

 

[Mr.Scagnattie]

I don't like IV oxy. It's pretty weak when administered that way in my opinion. No real rush..just kind of bland. I'd take IV morphine over it. Or better yet.. IV hydromorphone. %)

 

[80mg]

Dialudid is nice. That's odd to hear someone say that. MOST people I know love IV oxy.

 

[Mr.Scagnattie]

I guess it depends what they've done to compare it to. Once you've shot dilaudid, opana, or H.. IV oxy is just boring. Most people I know, if given a bottle of oxy, would just sell it and go by some dope or hydromorph.

 

[80mg]

I guess it depends what they've done to compare it to. Once you've shot dilaudid, opana, or H.. IV oxy is just boring. Most people I know, if given a bottle of oxy, would just sell it and go by some dope or hydromorph.

I guess it's opinion. I've done plenty of dope and still enjoyed oxy at high enough dose.

 

[Znegative]

I dont know.. I just feel that once you've injected heroin/oxymorphone/hydromorphone, you just can't call I.V oxycodone a "rush" as it seems an insult to the word. Despite the slight increase in BA over oral administration, I feel like shooting oxy is actually wasteful, as the high is so incredibly short lived.

The way I look at it is that oxycodone is to heroin what dextroamphetamine is to meth (when both drugs are injected). oxy and d-amp hit you immediately, but there is no rush, and the duration of the high is shortened drastically. Heroin and Methamphetamine are longer acting, and give very intense rushes.

 

[woamotive]

I agree with zneg, above. Oxy does not produce a rush. I have injected it more than a handful of times - not really because of the way it makes me feel, but because I like to inject ... period.

So, my answer is IV Morphine, by a mile. I don't personally know anyone that likes IV oxy, tbh. IV morphine has the lovely pins and needles feeling, head rush, etc. Then, after doing H - it's hard to appreciate 'rushes' (Other than Oxymorphone. Hydromorphone, even at very large doses, does not give me a rush) from pharma opiates such as these.-IME.

 

[tricomb]

I dont know.. I just feel that once you've injected heroin/oxymorphone/hydromorphone, you just can't call I.V oxycodone a "rush" as it seems an insult to the word. Despite the slight increase in BA over oral administration, I feel like shooting oxy is actually wasteful, as the high is so incredibly short lived.

The way I look at it is that oxycodone is to heroin what dextroamphetamine is to meth (when both drugs are injected). oxy and d-amp hit you immediately, but there is no rush, and the duration of the high is shortened drastically. Heroin and Methamphetamine are longer acting, and give very intense rushes.

Oh thank god you posted in here, I don't have to type out all my views now! I can just say ^ +1

IV Oxycodone is stupid and produces no rush, IV morphine on the other hand, is actually worthwhile, and is remarkably similar to heroin, just that it's not diacetylated. And trust me on a morphine drip, I don't know if one could handle a diamorphine drip unless they were dying of end stage terminal disease.

IV oxycodone = People with a needle fetish who's DOC happens to be oxycodone, and just because it produces effects IV'd, some even try to claim its a "rush". (unlike the example below, who appears to know his shit)

I agree with zneg, above. Oxy does not produce a rush. I have injected it more than a handful of times - not really because of the way it makes me feel, but because I like to inject ... period.

This proves what I'm trying to say.

IV morphine = gold standard for a reason, no ceiling limit at all, wins absolutely hands down. It's almost pathetic for oxycodone and morphine to be compared, it is not fair for the oxycodone.

It's basically like asking what feels better, IV Oxy (no rush, moderate dose-responsive curve, moderate analgesia) or IV dia/morphine (extreme rush, even better analgesia).

morphine just wins 10 times out of 10. Only thing that could beat it is hydro/oxymorphone which have less side effects, yet in many situations morphine's analgesia is still be stronger and an equipotent dose.

 

[The Dope Man]

as stated above dont shoot oxy. plug it or eat it.

IV morphine is my DOC, and doing a big enough shot will make your whole body feel like its being stuck by millions of flaming pins especially the bottom of your feet and your asshole. ( its very enjoyable dispute the gruesome description )

 

[kokaino]

IV morphine hands down! IV oxycodone produces no rush, whereas morphine produces a very intense rush. Plus, morphine is 2x more potent than oxycodone through the IV route. 10 mg morphine = 20 mg oxycodone.

This is really a one sided massacre in morphine's favor. Oxycodone can't compare to IV morphine, not one bit.

Uhm...I'd have to go with the Oxycodone. Although Morphine is nice I get more of a rush with the oxy plus it's easier to "cook" up (although you shouldn't really cook it). I'm pretty sure your going to hear this alot.

As for the codiene. Codeine has a ceiling affect of about 430mg. Anything mroe than that is a waste. But honestly your better off with the oxy even if it did go to 600mg.

There's no "rush" with IV oxycodone use.

 

[The Dope Man]

There's no "rush" with IV oxycodone use.

people confuse instant onset with a rush.

makes sense though. you go from baseline to high as fuck within a minute so I could see how someone could confuse that with a rush.

 

[kokaino]

^ Yeah I guess so. I think the more experienced IV users can tell the difference between a real "rush" and an instant onset.

 

[Mr.Scagnattie]

To qualify as a rush, it needs to happen fast and hard within a few seconds of the plunger hitting the bottom of the barrel.. that's what a rush is to me. There are then intensities, as far as how big the rush is like with hydromorphone vs. heroin.. however, the onset is still the same. Immediate. Even twenty seconds before it hits is way to long. I need to feel like I'm getting punched in the chest to call anything a rush.

 

[Swain]

I shot 90mg oxy the other day and I was dissapointed to say tyhe least. It wasn't even as good as a single bag of dope. There is absolutely no rush. A drug hitting you right away is not a rush.. try sh ooting a real speedball one day, heroin and coke, then come back and tell me oxycodone gives you a rush lol. If I had paid for these I woulda been let down but they were free.. other wise I never would have purchased them.

Lol I can't imagine how many 30mg oxy IR's I would need to get me as high as a bundle would. I remember oxy being comparible to dope but that was when I sniffed I guess..

 

[Mr.Scagnattie]

Yeah when snorted, oxy is pretty damn similar to dope.. but they are lightyears apart when IV'ed. No rush=not worth my time. And oxy produces squat in that department. Lame.

 

[kokaino]

Yeah when snorted, oxy is pretty damn similar to dope.. but they are lightyears apart when IV'ed. No rush=not worth my time. And oxy produces squat in that department. Lame.

Even when snorted they aren't much alike - the only thing heroin and oxycodone have in common is that they are both narcotic painkillers. Oxycodone is a thebaine derived semi-synthetic opioid, while "heroin" is an opiate and an ester salt of morphine (heroin = morphine diacetate), not to mention it is a morphine pro-drug. Heroin snorted is basically morphine, just like taking oral heroin is exactly the same thing as taking oral morphine. "Oral heroin" doesn't even exist. IV heroin is simply a faster acting form of morphine.

 

[tricomb]

Yeah when snorted, oxy is pretty damn similar to dope.. but they are lightyears apart when IV'ed. No rush=not worth my time. And oxy produces squat in that department. Lame.

This summarizes my views pretty fucking well. Although I do not recommend anyone chase this high, as I am stuck chasing it.


I agree that snorting a lot of oxycodone can feel pretty similar to waterlining some heroin (west coast=tar), because in lower doses they are both, to me, very stimulating. But with dope, once you hit a certain point it's nodsville.

If I tried to chase the oxycodone high (which is totally lame and not my cup of tea) I would overdose if I tried to take enough to feel like heroin.

 

[Znegative]

Even when snorted they aren't much alike - the only thing heroin and oxycodone have in common is that they are both narcotic painkillers. Oxycodone is a thebaine derived semi-synthetic opioid, while "heroin" is an opiate and an ester salt of morphine (heroin = morphine diacetate), not to mention it is a morphine pro-drug. Heroin snorted is basically morphine, just like taking oral heroin is exactly the same thing as taking oral morphine. "Oral heroin" doesn't even exist. IV heroin is simply a faster acting form of morphine.

Right, but doesn't Heroin metabolize not only into morphine when injected, but also 6-Monoacetylmorphine as well? But anyway, I found this on wikipedia:

Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and morphine. When compared to the opioids hydromorphone, fentanyl, oxycodone, and pethidine/meperidine, former addicts showed a strong preference for heroin and morphine, suggesting that heroin and morphine are particularly susceptible to abuse and addiction. Morphine and heroin were also much more likely to produce euphoria and other positive subjective effects when compared to these other opioids.

That was based on this article, which unfortunately I do not have access to due to a lack of subscription, but its an interesting study from the sounds of it.

 

[kokaino]

Right, but doesn't Heroin metabolize not only into morphine when injected, but also 6-Monoacetylmorphine as well? But anyway, I found this on wikipedia:

Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and morphine. When compared to the opioids hydromorphone, fentanyl, oxycodone, and pethidine/meperidine, former addicts showed a strong preference for heroin and morphine, suggesting that heroin and morphine are particularly susceptible to abuse and addiction. Morphine and heroin were also much more likely to produce euphoria and other positive subjective effects when compared to these other opioids.

That was based on this article, which unfortunately I do not have access to due to a lack of subscription, but its an interesting study from the sounds of it.

Heroin is also converted into 6-MAM (only when IV'd though). However, 6-MAM's half life is less than 5 minutes and it too is converted to morphine. Heroin is a true prodrug in every sense of the word. It is why the study you provided suggests what it does. The "two" drugs are really one and the same. Heroin is an ester salt of morphine (it is morphine diacetate). The heroin molecule is basically the morphine molecule with two acetyl groups added to it. All this does is make the morphine molecule quicker acting. Look at it this way: the two acetyl groups act as a propeller that drives morphine across the BBB faster than morphine would on its own. To put it simply, morphine is just getting a ride across the BBB at a faster rate in the form of heroin.

That same study also claims this:

In controlled studies comparing the physiological and subjective effects of injected heroin and morphine in individuals formerly addicted to opiates, subjects showed no preference for one drug over the other. Equipotent, injected doses had comparable action courses, with no difference in subjects' self-rated feelings of euphoria, ambition, nervousness, relaxation, drowsiness, or sleepiness.[10] Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and morphine. When compared to the opioids hydromorphone, fentanyl, oxycodone, and pethidine/meperidine, former addicts showed a strong preference for heroin and morphine, suggesting that heroin and morphine are particularly susceptible to abuse and addiction. Morphine and heroin were also much more likely to produce euphoria and other positive subjective effects when compared to these other opioids.[10] The choice of heroin and morphine over other opioids by former-drug addicts may also be the result of the fact that heroin (also known as morphine diacetate, diamorphine or di-acetyl-morphine) is an ester salt of morphine and a morphine prodrug, essentially meaning that they are identical drugs in vivo. Heroin is converted to morphine before binding to the opioid receptors in the brain and spinal cord, where morphine then causes the subjective effects, which is what the addicted individuals are ultimately looking for.[11]

Someone on Wikipedia obviously bought the paper, read it and quoted it.