i think alcohol is safe where it's at. It has the perfect range of effects and nothing can replace it's beauty. It is one of the most potent, fun drugs when done properly.
Anything else would never produce sociability as well as alcohol does. You drink, smoke and then have a coffee to sober up and hook up later.
There's a reason why they're all legal. They help each-other out.
Empathogens, hallucinogens, benzos, opies, stims come with such a variety of subjective effects that they will cause various communication barriers in a social situation.
from tripping out, to nodding off, falling out and motor-mouthing I don't see how they can replace alcohol in any constructive fashion.
Of course that's if the OP meant replacing alcohol for social situations.
For personal consumption I prefer everything else but alcohol.
The perfect drug combo(if they can make this into 1 drug) from my experience and IMO, - Your preferred stimulant in XR, your preferred benzo in a therapeutic dose, and alcohol's effects all in one.
This will obv be dangerous but like I said if it was placed into one drug so that taking 2 would be over-done then it produces the greatest effects. Besides some motor-mouthing.