I can only re dose if I start small. The only time I will want to re dose is when I'm at something like a concert, and want a longg smooth come up with a peak later on. This is the ONLY time I can be happy with a mild roll feeling(instead of strong) for the first 45min-hour.
I dose based on what I'm doing. Sometimes I just want to be really high, so I take all my pills at once and won't re dose. If I try re dosing, I get no positive effect AT ALL and feel way more Etarded and down afterwards. I personally don't roll very long naturally though, I come down way before most people do.
Other times(like I said), I'll take one good(not methy) pill at the start, another maby 35 minutes later and another maby 20-25 minutes later. This makes a nice floaty feel good come up, followed by a still nice and strong peak. I always take good pills though, when I know a current pill is really good and not methy I get a couple to save.
The only other thing I can think of(something I've never been into but I could see liking in the future) would be to take just one good pill in a social environment that I will be smoking (weed) in. It'd make for a more talkative warm experience. In the past if I didn't get fucked up from my pills I'd be angry I didn't get high enough, but I guess I'm seeing other uses for E.