Hi all,
I'm going to take Mephedrone on Friday night. I'm also on 30mg of the SNRI Duloxetine (Cymbalta) for depression, which is a fairly low dose.
I understand that there are theories that Meph releases serotonin and norepinephrine, which would be contraindicated with an SNRI.
My last dose of Duloxetine was very early Thursday (6am.) If I skip Friday's dose would it be theoretically 'ok' to use Meph on Friday evening? This would be about 42 hours since a dose of SNRI.
Anyone with any experience of this? Or any informed advice? Is this a deadly combination? I've read lots of conflicting reports. Some seem fine on it. Others say it blunts meph's affects, and others say it could bloody kill!
Thanks very much for any help. Really appreciated.
I'm going to take Mephedrone on Friday night. I'm also on 30mg of the SNRI Duloxetine (Cymbalta) for depression, which is a fairly low dose.
I understand that there are theories that Meph releases serotonin and norepinephrine, which would be contraindicated with an SNRI.
My last dose of Duloxetine was very early Thursday (6am.) If I skip Friday's dose would it be theoretically 'ok' to use Meph on Friday evening? This would be about 42 hours since a dose of SNRI.
Anyone with any experience of this? Or any informed advice? Is this a deadly combination? I've read lots of conflicting reports. Some seem fine on it. Others say it blunts meph's affects, and others say it could bloody kill!
Thanks very much for any help. Really appreciated.