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Is the ratio of serotonin depletion related to the intensity & euphoria of the roll?

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Greenlighter
Joined
Jun 21, 2013
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Is the ratio of serotonin depletion related to the intensity & euphoria of the roll?

Explaining why I got to having what I had:

So, in my country, they've been getting the legal highs going real easy and convenient back in 2008. The dumb kids abused them freely making an ass out of our system and getting into hospitals and dying and letting themselves get addicted, so they consecutively banned the good stuff specifically, only to be followed by similar weaker shit, and this specific ban happened a bunch of times till the media cooled down about it. So now the market has gone from the delightful weed imitations like he internationally known Spice and Tribe and Pulse to some shittier but almost weed replacing herbs, to having a nasty ass only gets you stupidly grinning and nasty tasting desperate ass would rather not have smokes unless coming down on the next issue. Same went with the MDMA-likes - they banned mephedrone (the mother of it all, my first roll, crazy safe and none of the never ending self doubting and hating comedown) and then consecutively put in weaker and weaker analogues developed by the labs, boiling it down to this short lasting very mild methylone-ish shit which almost doesn't mess with your sleepability or another speedy, hard to sleep after, nasty comedowny-unless you have plenty alcohol at hand and can stomach it (i do if i have to, i will take shots of the local moonshine if there is no option, until i puke into my mouth). Now I do not know what these derivatives actually are so I can look up their exact functions but my question is:

If I got a weak ass roll, did I use up all my serotonin but managed it poorly, or actually went gentle on it and still have some left (I do according o the mild hangover)? I always get tipsy before this to get more of the let loose ness of alcohol in it, which also potentiates it for me, and drink afterwards so I can drink/smoke myself to sleep


And please don't warn me about my liver, I don't do this often
 
oh yeah also, I did not roll for exactly a month prior to this, so that weak roll was "belong" to the material itself
 
Alright *bump* I see other questions being answered but not this. I figured it's a pertinent question and you know could work on my harm reduction. I am pretty set on getting some more for the second night (because I totally wasted the first one on dumb shit, wrong setting, wrong dosing, etc) and I know it's counterproductive in case of really euphoric stuff - squeezing the living daylight out of already milked out serotonin. But I was thinking milder effect means milder serotonin usage. So anyone? I'm sure some of y'all been into "bath salts" more than I have.
 
K. I can't really answer your question tbph, what I can do is give you information from what I've gathered. Methylone works similarly to MDMA. According to the wiki page, its affinity with serotonin transport is almost three times lower than MDMA, while dopamine and norepinephrine are similar. Take from this what you will.
 
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