Is 'ring substituted phenmetrazine derivatives as 5HT2a agonists such a daft idea?

[notornotFMAN]

BOB (11, A Lion Muzzled, A Clenched Fist] can be a very angry man.
However, he still thinks like [23, The [Hyper] Royal Star of the Lion] in many ways and is just as fierce.
I got love 4Bob.

Back to discussion topic
I do not want to try BOx's much and if I did I would aim the dosage even lower than normal. This stems from a negative impression I got from of ephredine tea from the people's rebulic of chinaland with taiwan in dispute.

I like pre-made Kool-Aid.

 

[fastandbulbous]

This leads to a question I asked a long time ago and never heard a response...with the BOx series...does anyone have an idea which isomer would be the active one with regards to the beta-MeO. And would that active confirmation correspond to this (in theory)? It is surprising that Shulgin did not work with the four isomers of the BOx series....considering many of the amphetamines are represented in the book as the racemate and individual isomers.

The BOx are only optically active about the beta methoxy carbon as they are phenethylamines, which are not optically active. It's the alpha-methyl BOx series where you'll end up with 4 different absolute configurations (all the threo/pseudo stuff gives me a headache). You'd think that one of the isomers would be a better fit though, all things considered...

 

[Morninggloryseed]

Woops, forgot the BOx series were analogues of the 2Cx and not the DOx.

Still, does anyone know which configuration of the BOx series is the most active?

 

[MattPsy]

It'll be the (R) isomer as I stated. Then you confused the hell out of me by saying they were amphetamines, lol.
But yeah, it's the (R) isomer - the amine points in the same direction as the (R) psychedelic amphetamines.

 

[hugo24]

It will surely fuck like a duck on your receptors