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Is my body likely to tolerate Cannabis ?

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Unlucky

Bluelighter
Joined
Apr 26, 2007
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Theres really no short way of asking this question without leaving a lot of gaps in the story and coming across as odd however I will keep it simple and answer the blanks areas if anyone asks..

Simple version... Im disabled with a neurologiacal illness and suffer with chronic pain, the restricted life has taken its toll on me and im at the point of suicide, I desperately need something aka weed to help me cope and manage the physical pain and emotional pain. However I cant just go and smoke it because I have a damaged autonomic system due to an overdose 10 years ago that left my body with a very unusual and frustrating chemical sensitivity to all substances that act on my autonomic system.

Last time I tried smoking pot 10 years ago I recall it made me feverish and caused my heart to thump like crazy , but this happened soon after I had developed the illness (autonomic dysfunction) when it was at its worst point and also the weed was the real strong stuff I was used to smoke regualrly before the OD. After several trials and adverse effects I realised and accepted my body was officially screwed and my drug days were over.

But now after 10 years I think there may be a chance I could tolerate it better even though I found it was not the case with opiates despite endless desensitisation trials. But maybe cannibis is different and what if I start of with just leaf (a method I havent tried before) ? would I be better off trying to acquire outdoor grown leaf as opposed to the skunky stuff ? Is it also possible to desensitise the body to cannibis and how should I work out the dosage, for my first trial would it be safe to say taking only just one puff from a joint indicate any potential adverse effects? If I remeber correctly I should stop before I feel anything as the effects are delayed ? If I have an adverse reaction is there anything I can take to counteract it such as maybe diazapem for the rapid heart ?

I know its an odd topic but beleieve me my situation is no short of being uniquely ridiclious.
 
I don't see how anyone here could say whether or not you could tolerate cannabis given your unfortunate circumstances (especially since you were deliberately vague in describing them).

What I can say, is that I think its a terrible idea for you to try cannabis right now due to your current emotional state. You mentioned how depressed you are, on the verge of suicide. That's terrible to hear and I truly hope you find some way out of this depressive state. However, in the meantime, I could EASILY see cannabis making you feel much much worse.
Cannabis tends to exaggerate whatever emotional state you are in. For someone who is depressed and desperate, cannabis could really due a number on you.

So, my advice is to steer clear of this particular drug. And please, do yourself a favor and pro-actively find an outlet (possibly therapy) so that you can address the issues in your life. Even if by some miracle weed made you feel a bit better, it would be a short-term fix, and would not address the actual problem.

Let me again stress though, I would be shocked if cannabis did not make you feel much, much worse given your current emotional state. Good luck-DG
 
The reason I was deliberately vague in describing the matters is because things are somewhat complicated with my condition and if I was to give my life story it could end up very long read jeapordising my chances of getting the answer I need as it is hard enough getting people to respond in this section of the forum as it is. Other wise Im quite happy to answer what ever else you want to know.

I dont suffer from schizophrenia or a chemical brain imbalance resulting in depression the only reason why I am suicidal and depressed is because of my disability and the chronic pain, ever since I became disabled Ive been stuck at home living with my parents with my life on hold, I've lost my independence and require my parents to take care of me with the tasks I can't do, I lost my work, all my friends ditched me soon after the disability, my chances of finding a relationship have diminished in my current state, I have to put up with some serious fked up symptoms every single day such as constant overheating and fevers for the past 10 years due to damage to my autonomic system which is unable to regulate body temperature, I have problems with my heart going ape shit just from standing up and postural changes due to the "postural orthastatic tachycardia syndrome" Ive been told there is no cure for my neurological illness, Ive been stuck with a stupid chemical sensitivity since the day I developed this illness which as result Im unable to even take the much needed opiates for chronic pain as aresult of expriencing severe adverse reactions, I went from being a raver who loved his drugs and dancing to becoming a vegetable stuck at home unable to do all the things I love, Im pissed of particularly with the chemical sensitivity which seems to be towards all stimilants, supresents, anelgesics, even alcohol, I feel like a minority in my condition and the fact no doctors been able to help me has further added to the frustration.

Of course Im depressed because of all this shit Ive had to put up with for the past 10 years, its because Ive hit rock bottom and, its nothing therapy is going to fix because the shit im stuck in does not have a cure, even if therapy put a smile on my face at the end of the day Im just a lonely disabled guy unable to live his life and it dosent get any better than that for me. Ive weighed up the odds in my head and realisticaly its either suicide or finding something to ease the pain and its taken me 10 years to decide on Cannibis so give me at least the benefit of the doubt and try and answer my initial question as much as you can please.
 
i know a lot about weed and let me tell you it is not going to help much in the state youre in... it is a drug that can very easily turn from a good high to panic and terrible thought loops. its all about your mindset, and yours is very negative. also longterm and/or frequent use ends up in agitation, anxiety, and depression.

smoking a weed leaf wont do anything to you. you have to smoke the bud. and yes take a little hit and see how that goes, then slowly work your way up

having said all this. its better than suicide. if you really believe there are no other options (and it unfortunately sounds like theres not) i would go for it. give it a try

good luck
 
Thanks for your advice, it seems I would need to give this more thought then. To avoid a "plesant high turning into terrible thoughts" can that be controlled by the amount you smoke, lets say if I was to settle for mild euphoria rather than getting really stoned ?

You also said the leaf wouldnt do anything, do you mean it is non active in structure or that it would be unlikly to cause me problems due to it being milder in strength ? Thanks again

Edit: Is the leaf also more likely to cause headches ? (something i vaguely remeber)
 
P.O.T.S. due to reflex tachycardia cuz your BP is always low, right? What do you take for this?

I think rimonabant blocks THC, though I'm not sure. For the sake of analogy, how do you respond to naltrexone?
 
seep said:
P.O.T.S. due to reflex tachycardia cuz your BP is always low, right? What do you take for this?
Click to expand...

Wow youve done your homework, impressive :)

With me however I have the variation that causes hypertension (high bp) rather than hypotension, my version a bit more rare according to my neurologist and autonomic specialists, I take betablockers to control my symptoms which reduces my bp and it controls my heart from flipping out every time i stand up, it rather masks the symptoms instead of curing it.

Naloxone and naltrexone is something I too have considered to try and control the adverse effects to opiates, but my specialist decided against it due to possible side effects that could make thinsg worse. i like the way you think by the way as its on similar grounds.
 
Seep I have just looked up Rimonabant and you are in fact right, it says

Blockade of Cannabis effects
Rimonabant blocks the psychoactive and some of the cardiovascular effects of Δ9-tetrahydrocannabinol (THC) in humans without affecting the pharmacokinetics

Sounds simply perfect as the cardiovascular effects was exactly what I was worried about, you are a true genius, thanks =D

The hard part is getting my doctor to prescribe the Rimonabant though without a valid reason 8)
 
The hard part is getting my doctor to prescribe the Rimonabant though without a valid reason
Click to expand...

Even harder as I'm sure it was withdrawn for having very dodgy side effects (try googling to find out which side effects - something to do with an increase in suicidal depression AFAIK).

Instead of smoking, which also introduced all sorts of shit like polycyclic aromatic hydrocarbons (naphthylene etc - all very nasty & carcinogenic; also do nasty things to the immune system), either get a vapourizer or try eating very small amounts to check for an untoward reaction. That way you avoid the nasty pyrolysis products
 
try googling
Click to expand...

Jesus, this thing appears in almost two million pages. Compare venlafaxine, modafinil, methylphenidate...

When I grow up, I wanna market a non-narcotic anorexant.
 
Ah well I should have guessed it was too good to be true :\

Thanks fastandbulbous, it seems a lot has changed in the 10 years since my days of smoking bongs and joints , I'd never even heard of a vaporizer till you mentioned it, what a sweet invention! I had considered eating as well but I'd heard the effects last a lot longer which isnt ideal just incase things dont go my way.

The funny thing is that Im going to try and score some shitty low grade weed as opposed to the sticky skunky stuff that I used to smoke 10 years ago, I can just see the dealers face when I tell him I dont want his good stuff and ask him for leaf or really weak low grade weed instead =D Life sure has a twisted sense of humour.
 
^ ok but are you sure good weed is better for me than the low grade stuff ?
I dont doubt what your saying I just need a bit more info what you said before I can decide, thanks.
 
cannabis caused postural orthostatic hypotension for me. it was kind of bad for a while, like for a couple years after i quit cannabis. i thought it was gonna permanent but it seems to have have improved quite a bit over the years (or maybe i've just gotten used to it?). all i know is that i don't notice my heart rate shooting way up anymore when i stand up. it was so bad when i was smoking weed that i could not stand up or walk when i was high. anyway for that reason im not sure cannabis would be a good idea for someone who already has POTS (i was physically healthy before cannabis but a couple of years of all day every day use resulted in this symptom for me).

i did try to reintroduce cannabis to my system after 6 months clean one time. the way i did it was by mouth smoking, a technique i read about on erowid. basically, you just hold the smoke in your mouth without inhaling and it is supposed to absorb through your mouth. it doesn't work well at all, which is why it can be used to deliver very small doses and test for negative effects. i never really got a high from this method though, and would invariably start inhaling the smoke. then i eventually relapsed into all day every day every use again despite the cardiovascular problems it was giving me. i finally quit after some very extreme negative reactions where i experienced severe stomach pain and nausea, chest pain, psychotic symptoms and significant weakness lasting for three weeks after a few hits off a joint.

its now been over four years since then, and i feel like i have recovered quite a bit. i am also considering trying cannabis again (i know that sounds ludicrous but i just love it so much) and would also appreciate any comments on whether or not i could handle it.
 
Just thought I would add that I tried cannabis a few days ago after taking rimonabant (got it online for weight loss) and I still felt fucked from smoking it and had to lie down afterwards, as usual, after each cone. Heart was pounding, etc. But don't remember having the psychedelic-type effects from it or the paranoia.

Though I did think I was having a stroke when my left arm became weak.... Seems better now though. I was laying on it funny at the time.
 
ok lol you guys have managed to scare the shits out of me =D

Burn out..awesome tip on holding the smoke in your mouth without inhaling, I was first reluctant making this topic due to its weird nature but now Im so glad cause you guys have given me some real valuable advice, cheers. The fact that you had some similar symptoms as me in regards to POTS suprised me, Im glad you shared your experience cause my body would probably react the same way as yours, I actually do recall now the last time I smoked weed 10 years ago I had to give it up because of the increased cardiovascular effects which never used to happen before the illness, so maybe this time round I can take an extra dose of betablockers with it that might control some of my heart symptoms.
 
Unlucky-
I hope that you decide not to try pot. I just can't see how it could possibly turn out well given your circumstances and current state of mind.
First, there is a very real chance that you will experience the actual physical symptoms you've had in the past (heart racing, temperature, etc).

And as I said earlier, even if physically you are fine, given your current state of mind, I can essentially assure you that the pot will exacerbate any negative feelings and emotions you are currently experiencing.
Pot isn't like a euphoriant or stimulant where the drug basically produces predictable effects each time. Pot acts as an exagerrating agent.
So, if you are in an amazing mood and about to see a concert and excited, the pot will exagerrate these positive feelings.
If however, you are depressed (for any reason), nervous, apprehensive (which you certainly will be due to your past experiences with pot)- its just going to end up exagerrating these negative feelings, and you will end up with a panic attack, paranoid, depressed etc.

I know this isnt what you want to hear, but Im just giving you what i believe to be the inevitable outcome of someone in your situation, experimenting with pot.

Now I am far from anti-drug. There might be some recreational drugs which could provide you with positive results. But in this case, pot just seems like an obvious disaster waiting to happen.-DG
 
daddysgone, I'm also considering your advice as its is valid, I need to think about this a little more before I preceed and if I do its going to be with great caution testing the water a little at a time.

Guys, thanks you all for helping me, youve all been very understanding with my weird condition, I really do apreciate it and Ive learnt a lot from the responses on this topic. I can now leave this thread satisfied that I have the information I needed.

Cheers <3<3<3
 
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