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Opioids Is it unheard of to use Loperamide(Immodium) to "get high"?

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Bluelighter
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Nov 7, 2010
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It might sound like a weird idea, considering immodium is supposed to harden your shit. But it is, in fact, an opioid-receptor agonist. And large doses can apparently cause effects just like any other opioid. I was just wondering if any of you have ever heard of anyone doing this. It would be a "cheap" way to get wasted probably, but you'd not shit for a year I'd imagine. But hey, I'm sure you've seen stupider shit done to get high.

LD50 ~250mg/kg and the dose is only 2mg btw. Not that 100mg or 200mg isn't dangerous.
 
I wish I could tell you. I have yet to try it myself but I've heard answers that range from "no not at all ever" "no not unless you mix it with X and X" "super high doses cross the BBB but the effects are mostly nausea and sedation with no euphoria" "yes i got a buzz when i took a lot"
 
The pointt is there is at least 1 death due to this in BL, its potentially neurotoxic and the amount that passes bbb is not predictable. Also the effects/potency in CNS are not well known.

Therefore -dont do it.
 
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The pointt is there is at least 1 death due to this in BL, its potentially neurotoxic and the amount that passes bbb is not predictable. Also the effects/potency in CNS are not well known.

Therefore -dont do it.

Yeah, actually, this thread has been covered so many times its insane. Some people get high off loperamide, others don't. It seems everyone can almost agree that it is an incredible drug for opiate withdrawal. My personal Experience is that in dosages starting around sixty mg, I will feel an opiate body high from loperamide, higher dosages do not increase this effect, nor make me feel 'euphoric'. I think it's easy to mistake feeling normal/not sick, with being high, especially when your not sure what to even expect out of this drug.
 
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