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Opioids is it the oxycodone or apap?

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smokerr

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Dec 5, 2010
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whenever i do oxycodone it is in the form of perc 10/325. i take 7 everytime i want to have a nice opiate nod. but then again i ALWAYS 100% of the time feel like im going to puke. so i usually load up on alot of ginger extract pills. but do you think it is the apap that makes me feel bad or the oxy? im taking over 2000 mg apap, which iss why i think it makes me sick tho i could be wrong. any help would be appreciated
 
It could be the APAP as that makes some people nauseous in high doses. Or it could be the actual oxycodone, you might want to try lowering your dose if your taking 70mg. Just because you do it one time and don't get sick doesn't mean the next time you do it you will fine. Opiates are weird like that, even normal users can get nauseous off their normal dose depending on what they ate and such.
 
Could be either one. Even though is probably worse for your body, the oxy is probably making you feel sick. Plenty of people puke after doing that much roxy (no APAP). Do you think you would get nauseous if you took that many Tylenol? I've taken a whole lot of Tylenol at once and never felt sick, but have done enough OC/roxy to feel sick numerous times.
 
70mg of oxycodone is a lot, it's definitely possible for that to be causing your nausea.

You can try a cold water extraction to remove most of the APAP.
 
It's not a good idea to take more than a gram (1,000 mg) of acetaminophen at one time, and the maximum daily dose is 4 grams (4,000 mg). It could be either one, the oxycodone or the acetaminophen, but I suspect that the acetaminophen is the culprit here, having myself taken more than 1,000 mg in one sitting before and having experienced the nausea you describe.

Cold water extracting the acetaminophen is a good idea. You might want to look into that a bit more.
 
Everyone is different with different answers to this particular question. Ive taken more than 1,000mg of Tylenol in one sitting & ive never gotten sick or anything. Imo, its the amount of oxycodone that is causing you to get nauseated.
 
Everyone is different with different answers to this particular question. Ive taken more than 1,000mg of Tylenol in one sitting & ive never gotten sick or anything. Imo, its the amount of oxycodone that is causing you to get nauseated.

Taking that much Tylenol is going to scar up your liver and do damage. You wont notice it until its too late.
 
I'd say it's almost certainly the oxy. Opiates generally do cause nausea if you take a bit too much. I've got an unusual sensitivity to oxy, and... if I take just a little too much, I feel nauseous. Take a bit less in the future. And if you're doing that often, you should CWE the pills, since it's not good to make a habit of consuming large doses of APAP.
 
When I began taking opiates, my DOC was Percocet also 10/325. Since I had no tolerance at the time, 20mg would have me quite high and I would puke most of the time. This was the case for a good 6 months into my use.

In your case I believe the 70mg of Oxycodone is the primary source of the nausea, but I wouldn't rule out the acetaminophen as a contributing factor. 2000+ mg an certainly cause nausea, in addition to giving your liver quite the workout. Th FDA just lower the maximum DAILY limit to 3000mg from 4000mg, but most agree that any single dose of 1000mg+ is harmful.

If you suffer from Gastritis, any amount of APAP or pretty much any NSAID(Ibuprofen as well)would most definitely cause severe nausea, which is my main issue when taking combination drugs like Vicodin or Percocet.

Th only way for you to truly find out for you specifically would be to perform a cold water extraction of the Oxycodone to eliminate most of the APAP from the equation.

You can do a search here for either cold water extraction or simply CWE Percocet to familiarize yourself with the procedure.

Good luck!
 
The liver can heal it self easily, even after serosis. Just do a CWE. And yes, APAP will make alot of people veru uncomfortable.
 
I was under the impression that the liver could not itself once it reached the point of cerosis however before that, it can.

I puke half the times I take opiates, whenever I take too much I puke.
 
I know I'm responding VERY late, and you most likely found your answer but...

I have to belive it was the APAP that made you sick. I had a script of what you have. Actually I've had 5/325, 7.5/325, and 10/325. Percocets (Oxycodone/APAP) and Vicoden or Narcos (Hydrocodone/APAP). I've never taken more then 12 pills in a 24 hour time period. I've only had to take 12+ pills when I had the 5mg ones. My tollerence was never that high.

Your daily limit (without poisioning or over dosing yourself is 4000mg of APAP) Yes that is a lot. 12 pills however is only 3900mg just don't take anything with APAP/Acetaminaphen/Tylonal in it. To be safe nothing with Ibprofin, OTC pain relif pills (actually called "Pain Relief" or "Pain Relievers") Asprin, Excederin, Naproxen, ect.

I don't know if they are cross tolertant, or add together for the OD factor, but they most likely would and if not make you sicker.

When I got into 8,9,10,11, and 12 pills I would get neasus. That's because I was very close to, if not over 3000mg of APAP. Anything under I was fine. At one time my tollerence was anywhere between 80-100mg of Oxy. Depending on how full my stomache was, what. I had eaten/drank, and a few other factors. One day I came across a script of 40mg Oxys. The kind that can't be broken down to be snorted or ived (I would have sniffed). So I popped two of them. So that's 80mg of Oxy and 0mg of APAP. The day before I had to take 90mg to get the high I wanted. I only had Percs 7.5/325 so I took 12 pills. I took them all, not having time to do a CWE (I wasn't home all day, and I wasn't at a place I was comfortable enough to do a CWE out in the open).

I had to take 3,900mg of that horrid APAP to get 90mg of Oxy, to get a good high. Back to my two 40mg oxys. My stomache was fuller being I didn't find my (remaining 5 or 6 40mg pills I had from a surgery a few months back) until about a hourish after having two PB&J sandwhiches and a large glass of milk. So I then took two 7.5/325 Percs. Brining my APAP total to only 650mg and my Oxy to 95mg. I now achieved my high, with less APAP then I have used to treat a migrain.

I told that short story to simply say one day I got 80mg of Oxy and a terrible stomache ache while the other day I got 95mg and NO stomache ache what so ever. That's why I CWE anything over 3000mg now. Well at the end of my binge. I'm clean now. Been alomst a full month. Quit taking 40-80mg of Oxy/percs/vicdones a day, and 3000-4000mg of gabapentin three times a week cold turkey (other then that I've only ever done weed which I quit years ago).

Imo APAP makes you sick and not the opiate itself. If you want a good high with no pukey feeling, and can't get the pure stuff do a CWE. The only down side is its liquid. No popping, no sniffing, and it taste horrible. You can mix it, but nothing more then you can finish it a decent sized sip. Chasing ddoesnt help the taste either. (Chase with White Grapefruit Juice. Hits faster and harder). Final downside it takes awhile to do and isn't something you can hide. The positives are, no more neasua. Its a liquid (can be an upside, so your not dealing with a handfull of pill. Also no having to swollow pills). And it hits hard and fast. Second fastest to iving, but its faster then sniffing. Last longer then sniffing and iving but not longer then poppin.

CWE is short for Cold Water Extraction. To make it short and simple pretty much do this. Crush all your pills into a very fine powder. There are MANY ways to do this. Be creattive. For awhile I crushed my with thr round side of a spoon. They have to be very fine. No halves, chunks, even grains. Almost powder sugar like. Like your ready to sniff, and then mor once you did that poor the powder. Into a freezer safe cup/small container. Fill with water, just coovering the pill. Then freeze until its cold enough, where its just before ice. If you have time put it in the fridge for 24 hours. Workss better imo. After you have yoour, very very cold pill powder water, stir it a bit again. Then plce a coffe filter, or folded paper towel on top of another cup. Filter works best. Make sure its sucured enough to stay when sonething is pured on to it. Now slowly pur your water from on cup to the other, THROUGH the filter. Very slowly. The water will go through, and a white goop will sit on the filter. The goop is the APAP. Drink the liquid and enjoy the buzz
 
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