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Is it possible to become immune to Suboxone? Because I am. It used to work.

titicaca2

Bluelighter
Joined
Jun 25, 2008
Messages
129
Location
Pacific NW
Why did bupe quit working for me?

Back when I smoked, I could smoke for three months, smoke at night, and when I would start to feel sick, I would take maybe 1-2mg of bupe and feel great. 18 hours later another 1-2mg, and that was it. I was done. No more withdrawals ever and i was sleeping through the need.

In fact, if you go read some of my old posts, I'm talking about this very thing. Oh how naive I was. "How in the world am I going to detox?!" With 2mg of suboxone and no discomfort, was the answer.

I did this several times and gradually I started needing more bupe, but I didn't think anything of it.

Then I didn't use bupe for about 9 months. Straight heroin, smoking for 6 months, then shooting for 3. The next time I tried to take suboxone it hardly took the edge off. All that happened was I DIDN'T shit or vomit. But everything else. The hot/cold chills, goosebumps, anxiety, malaise, insomnia, complete agony. I took another 8mg with no relief. I waited 36 hours in this state before caving and getting dope. I thought maybe I had done something wrong, maybe I fucked up. Maybe I hadn't waited long enough?

So a month later I checked into a (free local) detox clinic that used pure bupe 2mg pills. 36 hours later and 12mg down, my BP was 80/60 with a HR of 144. I was flailing and hadn't slept even for a second. They were going to send me to the ER, but instead my mom picked me up and took me to get dope.

She said seeing me like that scarred her for life. It was the most ill she has ever seen me.

Fast forward two more months where mommy checked me into a fancy rehab center 120 miles away. At midnight, the nurse had to call the doctor for special order because I was not responding to the suboxone. They put me on a 24mg a day dose the second day (first day on subs because I came in high), and the ceiling dose of 32 mg the next day. I was in agony. A nurse had to sit at my bedside to monitor me. They were sweet, putting hot or cold washcloths on my forehead to comfort me, changing my sweated out sheets, and rubbing my back. Again a dangerously low BP and high HR. I didn't eat for 4 days, and I didn't sleep for 7. Then I took a two hour nap. I was started on 50mg of seroquel for sleep, and incrementally every night when I would crawl to the nurses station at midnight to prove I was still awake, the doctor increased the dosages. By the 7th day I was on 300mg Seroquel, 150 Trazadone, and 100 Diphenhydramine. What a joke. I pretty much cold turkeyed. Except i didn't get the runs or vomit.Those dogmatic doctors wouldn't even give me a .25 Lorazepam.

Due to the fact that I had no escape, I kicked. And for the 30 days I was there I slept for a total of maybe 24 hours. I would hallucinate and dream while awake, I had no focus, my eyes were perpetually red, and I was exhausted, mentally and physically. I shot up the second I got home.

I used for a month straight, and here's where my story gets confusing. I was definitely strung out again. We went to a road trip to Idaho, I did my last shot in the morning. I took two klonipin and drank two beers and passed out at about midnight. I woke up at 5 in dopesick agony, I took one 8mg sub, and within 45 minutes, I was back to sleep with only mild sweats. The next day I felt alright, with only mild hot/cold flashes, and this was me on sub. Again, unfortunately, that night when I got home, I used. I've been using ever since and that was July. So about 8 months after that experience.

This morning was hell, I waited 24 hours and put one of the strips under my tongue, and within a few minutes I was puking. It was mostly the taste. Then I snorted about 3 mg in each nostril of 8mg orange suboxone. I waited 45 minutes, but when I had no relief, I did my emergency dope.

Just now I went back and read some of my former posts from 2009. 2mg's of sub detoxed me start to finish with almost no discomfort.

You guys tell me why? Did my brain figure out it was being tricked with a "partial agonist" and say "screw you thats not what I want!" Or is there a better explanation?
 
I'm going to move this to OD, they have more experience with Suboxone (and megathreads on it etc) over there.. hope that's okay :)

BDD > OD
 
I didn't mean to double post this, the different nature of the threads meant one could sit in BDD and one in OD. They aren't identical, but too similar to both be up. Mods do what you wish. I'm just desperate for answers.
 
A quick, straight from the hip, I'm starting to hear about alot of downfalls (unsucessful bupe' stories) when it comes to IV users & Methadone users(management or not) compared to all other full agonist opiates/opioids
Busy - may re: later
 
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A quick, straight from the hip, I'm starting to hear about alot of downfalls when it comes to IV users & Methadone users(management or not) compared to all other full agonist opiates/opioids
 
I been an opiate addict for 10 years. I currently been on Suboxone for 4 years, and i really feel it altered my brain chemistry, i no longer even mentally think about the feeling of being high on an opiate, or think about it. the only problem i suffer is physical withdrawl when i stop suboxone. both are opioids, if you want help, u gotta weigh out the benefits with the risks. i rather be dependent on a partial agonist that has a ceiling effect, rather then still be a heroin addict wondering if i would of died of an overdose already over the years,
 
I would be using the suboxone for a rapid taper and not as a replacement therapy. I just need to kick. I have a fulfilling life full of natural endorphins waiting for me... I go to the gym, I have a healthy (non drug related relationship), an excellent job that drug tests... Hell... people's lives are in my hands. I get adrenaline rushes. I don't even really like the dope anymore, I sleep too much. I miss homework assignments.
 
After I w/d from bupe, I tried 4 mg a couple months later and it didn't do anything except make me slightly irritable.
 
I was looking up if this has happened to anyone else. Apparently I'm not the only one. When I first took suboxone I was only smoking heroin maybe a half to a gram a day for about 9 months. I took the suboxone and literally had not one withdrawl symptom. Throughout the next several years I repeated that pattern and it always worked. Then went on a 2.5 year binger and eventually started shooting up about three to four grams a day. I actually went back to smoking I know to most addicts that's weird but I just got sick of finding veins. And once I started smoking I was doing about 6 grams a day. Then I decided it was time to get clean. I had my mom take me out to our family ranch in the middle if nowhere but honestly thought id be fine cuz I had plenty of suboxone. Fuck my life. I literally had every symptom and then some. I almost shanked my mom with a knife to try to get the keys to her car it was that bad. I also don't handle it well to begin with but I was kind of shocked. I am not sure what happened. Was it because my tolerance was so high or I was using so much? I also had an experience where I took suboxone to early and literally almost had to get my stomach pumped. I violently threw up non stop for almost ten hours. I thought maybe that had caused me to become immune. However. I did take subutex the version without narcan, about six months before I had gone to the ranch. And it worked amazing. So now I'm on dope again and I'm terrified to get clean cuz I'm afraid the only way us to cold turkey. Does anyone actually know the answer to this??? And if I become immune to suboxone will subutex still work??
 
repeat heroin relapsers who have been on suboxone, got kicked off, got back on it, back and fourth, is clearly not for them! i would know! i was on suboxone, just knowing i had 90 subs and could make enough $ to get a whole fuckload of dope got the best of me..at one point, ii saved 1 sub A DAY, sold the rest of my subs, and smoked it all up hooked on crack..everytime i get clean i think suboxone is gonna help save me..wrong..time to try methadone..
 
4 or 32 mg, it don't make a damn difference. The detox is obviously dumb as fuck. Ceiling dose is 32 mg my ass, maybe for blocking purposes but not for its agonist effects. If your tolerance is really high then the bupe isn't going to do much to ease withdrawals. It'll do something, but you still have to deal with the time for your tolerance to drop. If it is unbearable then you should probably use methadone as a maintenance drug
 
4 or 32 mg, it don't make a damn difference. The detox is obviously dumb as fuck. Ceiling dose is 32 mg my ass, maybe for blocking purposes but not for its agonist effects. If your tolerance is really high then the bupe isn't going to do much to ease withdrawals. It'll do something, but you still have to deal with the time for your tolerance to drop. If it is unbearable then you should probably use methadone as a maintenance drug

If you wait a good 36 hours or better yet closer to 48 hours then you should be sick enough that suboxone should help. So often times it comes down to whether you want to take the sub before you get that sick, which can just keep you from getting sicker but still have you feeling shitty, or you can bite the bullet and feel like shit for a day to allow for the sub to work well when you take it.

If it's your first handful of times getting on bike then that doesn't apply as much considering your habit isn't too high, but once you go back and forth too many times and/or have a habit that's out of reach for the ceiling dose of bupe to touch then you are going to have to go through at least some discomfort before it gets better. Whether you want that to be one really bad day or 2-3 moderately bad days is going to depend on when you decide to dose it.
 
Many people have experienced this, I've been on and off Suboxone for 8.5 years, since late 2005...

I had no problem inducting on the Suboxone for the first few years, but for a long time now, the Suboxone takes a long time to work no matter how long I wait....And, it takes me 3-4 days to 100% work...when it finally does start working though, it still works well..

Jacking the dose up doesn't do shit, it just takes time..I keep taking 2mgs every 12 hours or so until iI finally start to feel halfway stable, then I'll switch to 4mgs every 12 hours for a few days...Once I'm finally stable, I can jump right down to 2mg twice a day, but getting there is a bitch! It really does seem like the bupe "doesn't work" anymore..

If you can make it 3-4 days, you're almost better off just kicking everything in some cases, but I currently need the crutch of maintenance right now...I've been dependent on opiates for so long, I feel normal being dependent on them..

I was off everything for 1.5 years up until last winter...I shot heroin for 2 months and ended up back on bupe...It has very few side-effects for me, and I can still feel emotions more than with methadone, and have a sex drive...although, if you can stay relatively low on the methadone dose, it's not too bad...

Being on OTR isn't perfect, it's a big compromise you make with yourself...but it's 100x better than being stuck with a dangerous habit that you can't afford and are unable to quit!
L
 
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