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Benzos Is coloznapam dissolvable in Nail Polish remover?

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free67molly

Greenlighter
Joined
Sep 13, 2012
Messages
2
I know this sounds like a stupid question but i'm desperate to get high
is nail polish remover a good substance to dissolve 2mg of coloznapam in ?
 
free67molly said:
I know this sounds like a stupid question but i'm desperate to get high
is nail polish remover a good substance to dissolve 2mg of coloznapam in ?
Click to expand...
No; absolutely not. Nail polish remover is poisonous-and why would you want to waste a clonazepam by throwing it in a bottle of polish remover?
 
If its just acetone with nothing else in it, then yes. Benzodiazepines are soluble in alcohols, like etoh (ethanol), isopropyl (rubbing alcohol), and methanol (alcohol you don't fuck around with unless you know how to handle it lest you risk blindness/death).

The problem is, most "nail polish remover" isn't the required dry, pure acetone that is necessary for what you want to do. If you can find the msds for that particular brand, and it only contains acetone, without much water or other ingredients added go for it. If you don't, you risk ingesting poisionous chemicals that could cause serious health issues. Best to get dry acetone, or another dry alcohol like isopropyl if you want to "extract" benzos from pills.

As far as why you would want to do that i have no idea. The bioavailability is close to 90+% orally/sublingually, and if your thinking of shooting it just stop now. Get Propylene glycol, research how to, and do it the right way. If your going to plug the alcohol/benzo solution, well, thats a shitty idea as well if you like your ass not burning like you stuck the nozzle of a mace sprayer up there and went to town. Smoking benzos aren't as effective as oral/sublingual, and snorting alcohols will burn as much as putting them up your ass.

If your doing it to dose it volumetrically, i can understand. But from your "desperate to get high" statement thats a very low probability.

The best solvents for extracting benzos from pills (which is pointless anyway given their high oral/sublingual bio-availability) is PG (propylene glycol), which you could plug without the pain of alcohol, or etoh (ethanol). PG works good for raw benzo powders, but thats not the case with what you seem to be attempting (extraction from pills)

Just eat your kpins and stop trying to get higher than is physically possible with them. You'll end up wasting them, and/or getting sick trying to do otherwise unless you have the right, pure, food grade/clean solvents.
 
There is no reason you would ever concievably want to dissolve clonazepam into acetone for ingestion, don't do it.

Acetone is not meant for eating, drinking, injecting, or snorting.
 
sekio said:
There is no reason you would ever concievably want to dissolve clonazepam into acetone for ingestion, don't do it.

Acetone is not meant for eating, drinking, injecting, or snorting.
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Acetone is not all that toxic, and if your talking like 1ml or less i doubt its going to do any harm (pure acetone that is, NOT nail polish remover). Remember its a part of the body's metabolism, and its ld50 (human) is like 1.16g/kg. So 40+ml for your very small 50kg adult. Prob 60~ml for an average person. Under 1ml, i'd hazard a guess its safe, and 2mg clonezapam would dissolve in that amount.

But really, don't use acetone, if any alcohol use etoh. Better yet Propylene glycol witch is safe for consumption. LD50 on that is 20ml/kg in rats. Etizolam at 1-2mg/ml, or clonazepam at 1-2mg/ml works good. But thats really only worth it if you want to plug/inject it. And in that case of injecting, you HAVE to be sterile. Plugging pg dissolved benzos works pretty well though, and its used to treat epileptic seizures w/ benzodiazepines in PG liquid suppository's.

The reason for this is injections are not practical w/o a nurse present at the time, and i remember watching a video about a child with severe epilepsy having a seizure at home, and his father gave him a suppository of Valium(iirc) PG solution intra-rectally. So it has to be faster hitting than oral/sublingual, or they would just give him it orally. I'd imagine injection is the fastest hitting roa, just not practical/necessary/smart in all but medical emergency situations. Really the only time imho benzos should be administered Intravenously in PG.
 
If you are desperate to get high then clonazepam isn't the answer. This risk involved with using nail polish remover or other solvents to make a solution (other than medical grade prepared vials) for IV or IM is not worth the reward. You won't get a rush, and the IM and IV bioavailability are barely higher than the oral BA.

Clonazepam was almost completely absorbed after i.m. and p.o. administration, as shown by the mean absolute bioavailability of 93 and 90%, respectively (source).


What exactly is your plan? Were you going to mix nail polish and clonazepam pills to IV them like most of us have assumed? Please don't. Sublingual administration may have a faster onset than oral administration while maintaining the high bioavailability.
 
Last edited:
Mother of God.

Don't attempt to dissolve clonazepam in acetone. I don't know where you got the idea, but IV clonazepam, even with a correct/safer solvent it's a moronic idea. Just because you can do something, doesn't mean you should. Why would you want to IV clonazepam?? I know it has a slow onset, but you can't force effects out of a drug that don't exist by shooting it up.

If you aren't satisfied with the sublingual/oral effects of clonazepam, direct your attention elsewhere, clonazepam is obviously not the solution for you. If a benzodiazepine with 90% oral BA doesn't work for you, it's the drug to blame, not the ROA. Benzodiazepines were formulated for best results taken orally/sublingually, they are only given as an IV during emergencies.
 
tricomb said:
Mother of God.

Don't attempt to dissolve clonazepam in acetone. I don't know where you got the idea, but IV clonazepam, even with a correct/safer solvent it's a moronic idea. Just because you can do something, doesn't mean you should. Why would you want to IV clonazepam?? I know it has a slow onset, but you can't force effects out of a drug that don't exist by shooting it up.

If you aren't satisfied with the sublingual/oral effects of clonazepam, direct your attention elsewhere, clonazepam is obviously not the solution for you. If a benzodiazepine with 90% oral BA doesn't work for you, it's the drug to blame, not the ROA. Benzodiazepines were formulated for best results taken orally/sublingually, they are only given as an IV during emergencies.
Click to expand...

This pretty much sums it up. There was an unintentional pun in there too, so I made it bold. =D
 
chemical ali said:
i have shot clonazepam using vodka. you get way higher taking them orally and the onset is only 5-10 minutes. dont waste your drugs.
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So of course we're all irrationally stubborn at times. It's funny I come across this thread because I diluted 3mg lorazepam (:() in vodka/water @10% ethanol. Micron filter, load rig and shoot.

'Raspberries!'
'Well, Red Berry.'

I didn't see a flavor on the label but when I shot it, I could taste it in my lungs.

You already know, it wasn't worth the prep time for marginally faster onset. If you have a bit of a needle fixation, do all you can to reduce the long-term harm. Keep a bottle of straight vodka on hand. Or read labels.

(It tasted great.)
 
Don't inject alcohol at all; it can cause metabolic acidosis and vein damage. Nothing more than ~1% benzyl alcohol should be used in IV shots.

At least you micron filtered it.
 
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