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Insomniacs out there? what do you take?

^i can't disagree more with that. ampoules are obviously by far the best form.
 
^^^^ Or just the raw chemicals themselves, granted you need a hell of a scale for some, but I got a Sartorius 2340 accurate to 100µg and acces to ampoules, so I'm a praised man :)
 
I have almost zero benzo tolerance, I only do them about once a month for a few days, but when I do it takes large amounts to help with sleep. 4-5mg Xanax did almost nothing for me, I finished my 30mg months supply in about 6 days, Oxazepam is a joke, the only thing that really works is 30-45mg of Midazolam. The problem I have with Midazolam is I've taken enough to "knock me out" and woken up the next day and found most of my stash missing (8 x 15mg). I find it sometimes also works well for about 2-3 hours and then I wake up.

What works really well for me is OTC antihistamines (doxylamine, cyclizine) but I wake up with a hangover the next day. I once had to get a promethazine IV injection because they thought I might be allergic to a painkiller (d-propoxyphene) and that made me deliriously nod for about 6-8 hours so I think I might be overly sensitive to antihistamines. I don't get any hangover at all from benzos so I would prefer to use them.
 
center said:
^ Are you actually bragging?

Lmao.
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Nope, my Gallery provides all the proof, not that it matters to you anyway since you're banned. :)

hexxx said:
I have almost zero benzo tolerance, I only do them about once a month for a few days, but when I do it takes large amounts to help with sleep. 4-5mg Xanax did almost nothing for me, I finished my 30mg months supply in about 6 days, Oxazepam is a joke, the only thing that really works is 30-45mg of Midazolam. The problem I have with Midazolam is I've taken enough to "knock me out" and woken up the next day and found most of my stash missing (8 x 15mg). I find it sometimes also works well for about 2-3 hours and then I wake up.

What works really well for me is OTC antihistamines (doxylamine, cyclizine) but I wake up with a hangover the next day. I once had to get a promethazine IV injection because they thought I might be allergic to a painkiller (d-propoxyphene) and that made me deliriously nod for about 6-8 hours so I think I might be overly sensitive to antihistamines. I don't get any hangover at all from benzos so I would prefer to use them.
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Xanax is a shitty benzo to help you sleep, that's why it isn't classed as a hypnotic. Seresta is shitty as a hypnotic too, an for that reason it isn't classed as a hypnotic either. Now Dormicum, that is one hell of a hypnotic, hell, it's a damn pre-anesthetic. They use it to induce general anesthesia with in the same dosage as the strongest avaible tablets, just 15mg is enough to literally put you in a come when used IV. I've had the 15mg Dormicums on prescription for some while, and I've had it happen plenty of times that I looked back at the previous night and after a certain time it would all be blank, which was enough of a suggestion that I've probaply taken Dormicum again, or otherwise my prescribed Rohypnol.
 
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I got a 6 months supply of Dormicum 15mg prescribed but it doesn't help much because I need >3 a night just to sleep. I was in a bad car accident 3 months ago that left me with a shattered pelvis and several other fractures. I really struggle to sleep because of the discomfort so being anaesthetised is pretty much my only option. I might ask my doctor for something stronger (Rohypnol?), he is pretty sympathetic and pretty much just asks me what I want to help me sleep. I was an insomniac before the accident as well to compound things.

My only worry is after a few days of taking benzos I feel a bit crazy and my thoughts are very strange and different (in a negative way) from how I normally feel without any chemical influences.
 
Even though Dormicum has an extremely short half life(just a few hours), it will build up a lot when taken in high doses, and because of it's ultra short duration, it causes a massive raise of one's tolerance in a short time, so you'll start out with half a 7,5mg tablet and end up taking several of the 15mg tabs.

You would have been much better off with intermediate to long acting hypnotics, even in higher prescribed doses, than on Dormicum, Dormicum is the last resort really, and very nasty to taper from. Did your doctor try out other hypnotics before you got Dormicum? If so, which? If not, you should advice him to switch to an intermediate to long acting hypnotic instead, since they don't cause a rise in tolerance as fast as Dormicum.

If your problem is falling asleep because of the pain, fast acting knock out benzo's like Dormicum are the most effective, and you'll be needing higher equivalent doses of intermediate to long acting benzo's, but you'll be much better off in the long term. After all, you can't keep raising your dose for the rest of your life, which means one day you'll have to taper down, and tapering down from your dosage of Dormicum is really awfull, and possibly fatal if not done very slowly.

It is one of the known side-effects of benzo's to worsen depression in people who are already depressed, which if normal if you suffer a lot of pain. There is a difference between benzo's in it's effect regarding this though, Rohypnol will probaply cheer you up instead, I've experience similar effects with Dormicum and other short acting hypnotics, though milder, while Rohypnol had a positive effect on me throughout the following day. Good luck.
 
phatass said:
too short acting... ask for a longer nacting benzo... u know what they are...;)
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Yep, Iam prescribed klonopin 2mgs to take at night too, maybe I should switch back to that, or take both, i just have been trying to keep my benzo tolerance low, Ive been taking the xanax because they knock me out SO FAST, the Klonopin take 2 hours to start working but than I sleep, maybe if I took a 2mg xanax too knock me out and 2mgs of klonopin to kick in while iam already asleep, to keep me asleep. maybe I will try that.

Im prescribed 6mgs of xanax a day but only take 4mgs a day(2mgs in the morning and 2mgs at night) and iam prescribed 4mgs of klonopin a day and I only take 2mgs of klonopin a day (in the morning with my xanax)
 
I Am Prescribed Methadone Clonazepam And Ambien......they All Work For Me, Even If I Took Either Or.....but Over The Counter Wise...hmmm, Nothing Would Work For Me, But You Could Try The Over The Counter Stuff Check Em Out, But I Would Go With The Clonazepam, Or Xanax Myself...but Ambien Is Easy To Get From The Doctor....just Tell Him What You Say On Here......
 
phatass said:
too short acting... ask for a longer nacting benzo... u know what they are...;)
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Alprazolam has a duration of 12 hours. It has a very short half life compared to most other benzo's, and because of this a lot of people still think it is of short duration as well. But it has been proven on trial subjects that it lasts around 12 hours in the average person. All the doctors say it's short acting, but they have never taken in themselves, and certainly haven't rigorously tested it on themselves and others. Xanax is not short acting.
 
6mg melatonin + 1,000mg GABA + 5mg zolpidem

if that doesn't work, another 5mg zolpidem

if that doesn't work, 5mg diazepam

if that doesn't work, at least i'm a little stoned from the ambien & valium 8)
 
Don't think it was just in my head because, say I was doing a twice daily dosing, if I missed my second dose, sometimes I wouldn't realize I had missed it til I was unable to fall asleep, or suddenly started feeling uncomfortable for no reason.
 
I just use whatever benzo i can get to help me sleep.

but i prefer halcion or temezepam, their super strong.
 
xanax but they only help once i do fall asleep, What i meen is they dont make me tired when im awake but when i do fall asleep i sleep for like 24 hours
 
You should try hypnotics instead. Anxiolytics generally do a poor job in helping you fall asleep unless you're very sensitive to them or take them in high doses(much higher doses than their equivalent doses of a hypnotic). Taking anxiolytics in high doses as a sleep aid will cause much more negative effects like a drowsy, tired feeling the next day, and having a lot of trouble getting out of bed. In the long term but even in a relatively short period they'll cause a much larger rise in tolerance and worse physical dependancy compared to taking hypnotics for insomnia, because they are much more effective sleep aids, and so need much lower equivalent doses.

Hypnotics are generally a lot more physically addictive than equivalent doses of anxiolytics, this is due to their much stronger effects, because they bind differently to the GABA-benzodiazepine receptors than anxiolytics. This is also why hypnotics have much higher acute toxicity than anxiolytics. A lethal overdose on anxiolytics by themselves(without any other CNS depressants) is almost impossible, but a lethal overdose on hypnotics by themselves(without any other CNS depressants) is much more real, and a very real possibillity with the strongest intermediate acting hypnotics like Rohypnol, Loramet, and Normison, and the short acting hypnotics like Dormicum, Dormonoct and Halcion. But still, taking a lot lower dose of a hypnotic is much more effective and beneficial than taking a high dose of an anxiolytic.
 
Psych0naut said:
You should try hypnotics instead. Anxiolytics generally do a poor job in helping you fall asleep unless you're very sensitive to them or take them in high doses(much higher doses than their equivalent doses of a hypnotic). Taking anxiolytics in high doses as a sleep aid will cause much more negative effects like a drowsy, tired feeling the next day, and having a lot of trouble getting out of bed. In the long term but even in a relatively short period they'll cause a much larger rise in tolerance and worse physical dependancy compared to taking hypnotics for insomnia, because they are much more effective sleep aids, and so need much lower equivalent doses.

Hypnotics are generally a lot more physically addictive than equivalent doses of anxiolytics, this is due to their much stronger effects, because they bind differently to the GABA-benzodiazepine receptors than anxiolytics. This is also why hypnotics have much higher acute toxicity than anxiolytics. A lethal overdose on anxiolytics by themselves(without any other CNS depressants) is almost impossible, but a lethal overdose on hypnotics by themselves(without any other CNS depressants) is much more real, and a very real possibillity with the strongest intermediate acting hypnotics like Rohypnol, Loramet, and Normison, and the short acting hypnotics like Dormicum, Dormonoct and Halcion. But still, taking a lot lower dose of a hypnotic is much more effective and beneficial than taking a high dose of an anxiolytic.
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All of that is fact, and is what I have been saying (and bringing scientific studies to back up all the claims that the hypnotics are on another level, a level more akin to barbiturates). However, a few posters (one of which was the narutokin - a prebuscent kid with severe mental issues and a fetish for needles, he'd IV his piss if he thought there was some kind of metabolite in it, thinks that I am "wrong" LMAO).

Benzodiazepines produce a range of effects from depressing to stimulating the CNS via modulating the GABA(A) receptor, the most prolific inhibitory receptor within the brain. The GABA(A) receptor is made up from 5 subunits out of a possible 19, and GABA(A) receptors made up of different combinations of subunits have different properties, different locations within the brain, and different activities relative to pharmacological and clinical effects.

Benzodiazepines bind at the interface of the α and γ subunits on the GABA(A) receptor. Benzodiazepine binding also requires that alpha subunits contain a histidine amino acid residue, (i.e., α1, α2, α3 and α5 containing GABA(A) receptors).

In order for GABA(A) receptors to be sensitive to the action of benzodiazepines, they need to contain both an α and a γ subunit, where the benzodiazepine binds at the interface. Once bound, the benzodiazepine locks the GABA(A) receptor into a conformation where the neurotransmitter GABA has much higher affinity for the GABA(A) receptor, increasing the frequency of opening of the associated chloride ion channel and hyperpolarizing the membrane. This potentiates the inhibitory effect of the available GABA, leading to sedatory and anxiolytic effects. As mentioned above, different benzodiazepines have different affinities for GABA(A) receptors made up of different collection of subunits. For instance, benzodiazepines with high activity at the α1 (BZ1 or omega 1 receptor) are associated with sedation, hypnosis, amnesia, toxicity, motor impairment, cognitive impairment, whereas those with higher affinity for GABAA receptors containing α2 and/or α3 subunits have good anti-anxiety activity. Benzodiazepines also bind to glial cell membranes.

There are two central benzo receptor subtypes, as described above, (BZ1 and BZ2), and one peripheral Benzo receptor has been identified and well studied and researched.

Diazepam, alprazolam, bromazepam, lorazepam, prazepam, oxazepam, clonazepam, and clorazepate are strong BZ - 2 receptor (omega 2 receptor) agonists. Omega 2 receptors mediate moderate to strong anxiolysis and some anticonvulsant activity.

Triazolam, temazepam, nitrazepam, flutoprazepam, nimetazepam, flunitrazepam, and lormetazepam are strong BZ - 1 receptor (omega 1 receptor) agonists. BZ - 1 receptors mediate hypnotic effects, anxiolysis, powerful sedation, amnesia, anticonvulsant activity, euphoriant activity, motor-impairment, cognitive impairment, and ataxia.

However, ALL benzodiazepines have affinity to both omega 1 and omega 2 receptors and all benzos bind to both, just that some bind to BZ1 much more strongly (the hypnotics) and some bind more strongly to BZ2 (the anxiolytics).

The "Z" hypnotics are BZ1 or omega 1 selective, but they bind to a subgroup of the BZ1 (omega 1 receptors). They don't bind to what temazepam, flunitrazepam, nimetazepam, nitrazepam or flutoprazepam bind to - oh hell no!!
 
Recently I've been having excellent results from the simple combo of warm-milk and melatonin. My only issue is that the melatonin leaves me feeling drowsy and sluggish for a good 6hrs or so into the next waking-day.
 
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