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Opioids Injection of Oxycodone 2 hours after the last - same mg, no rush

C

commonbondage

Greenlighter
Joined
Jan 6, 2012
Messages
4
Location
Hawaii, USA
Hi guys! This is my first post, although I have been coming to the forums for years now for all my "research" questions. onto my question.

I just began injecting opiates a couple weeks ago. I has tried tar a few times, however I do oxycodone more often. Anyways, I am a bit nervous since I does in fact realize the dangers of this step, so I have been only injecting, like, 15mg at a time.

I decided a couple hours ago to try 30 mg this time. About a minute after the shot, I felt the strongest craziest rush I have ever felt off anything.. It actually freaked me out a bit. so, then NEXT time, I used about a quarter of a pill less, and paused half way through for a minute just to check myself a bit.

And- I felt NOTHING. Barely a buzz afterwards. No rush AT ALL. Why such the dramatic difference?

Just for some other details- The time I got the major rush, I was using a vein in my hand, and the second time was my arm. I also smoked 3 or 4 hits of Meth a couple hours before the first one.

Anyways, a little insight would be cool, and I'm really excited to be a part of the community (finally!)

EDIT to remove "alter ego".. but, seriously? Not even a "welcome!"... you all seemed friendly in other posts I read, and instead I get counciled right off the bat, and not one word of input. :(
 
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Is this about you? Cause if it is please edit it accordingly. Writing SWIM or my neighbour down the street's dog does nothing to protect you and is a pain to read. We don't allow it here.

And if this is a legitamite situation we will be able to help you much easier when we are reading facts.
 
Oh! I'm so sorry.. In all my reading I saw SWIM so much, I thought that was what I was supposed to do. In fact, in another drug forum I read, they say specifically that SWIM isn't ENOUGH to protect yourself. Perhaps that's because the other forum is a US based website? Who knows, alright, well I apologize, I thought I was being coy.
 
Could you please edit your post. There is no way to protect yourself. If you read the Other Drugs guidelines it explains all the rules of this forum.
 
To be quite honest, I never ever really got a rush IV'ing oxycodone. It certainly wasn't anything like heroin/morphine, fentanyl, hydromorphone, or meperidine/pethidine (Demerol). Oxycodone doesn't provide a real "rush".
 
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Apologies, but i couldn't offer input on this one due to the fact that I don't IV. Requesting you to edit your post was so that you would get more responses.
 
Well, I've only ever iv'd tar and oxy, so I don't really have anything to compare it to, but it was a massive "woah" had to sit down, light headed,overwhelming kind of rush. Super intense.. could it have been something else perhaps? Like maybe my body reacted badly to it, and I almost pased out, rather than it actually bing a "high" kinda rush? I've never quite felt anything like it. I mean, it did feel good, but it was more frigtening tha anything cause it was unexpexcted.
 
Hey man, welcome to bluelight,

oxycodone does not really produce a rush, just an immediate onset. I imagine what happened the first time was that you used too much, so the high seemed overwhelming. A " rush" happens with dilaudid, oxymorphone, and heroin among others and it usually occurs 5-20 seconds after injection (though with certain opioids like buprenorphine and morphine there is a slight delay). Most people that get a rush out of oxycodone do not have adequate experience with other IV narcotics, or have a really low tolerance.

However, the reason that you second injection was not as powerful was probably because you 1)used less, and 2)you didn't wait an adequate ammount of time for your opiate levels to drop, so the second dose just added a little to the first one.

When I shoot heroin (or any opiate), I find that in order to get the best high and rush, I need to wait until the last shot has worn off almost completely and I'm at the cusp of withdrawals. If I do a shot 2 hours after my first, I will get a weak rush (if any) and I just become more sedated. Also, which vein you shoot into doesn't make much of a difference in terms if how good the rush is. Shooting into you arm is the safest though, I wouldn't fuck with the hands if you still got your basilic and cephalon veins.

Anyway, you might want to consider switching back to insufflation or oral for oxy. IV only gives you about 20% more oxycodone, and it shortens the duration by at least an hour, if not more. With oral, you can also increase absorption by using potentiator's such as Benadryl and

Hope this helps
 
The thing is the more lipid soluble (fat-soluble) an opioid is the more intense the rush is going to be (due to a faster onset of action). IV oxycodone is not as lipid soluble as drugs like morphine/heroin, hydromorphone, or fentanyl. Fentanyl and hydromorphone are extremely lipid soluble, so you can expect a very intense rush with these two drugs. Oxymorphone is a little less lipid soluble compared to hydromorphone and fentanyl, so a less intense rush. Heroin is only slightly more lipid soluble than morphine, but it is a morphine prodrug. So it initially crosses the BBB a bit quicker than morphine would, but as soon as it crosses the BBB it is converted to morphine and morphine takes action and is responsible for the high. Only a very, very small % of heroin is converted to 6-MAM, which itself is quickly converted to morphine also.

Drugs like oxycodone or hydrocodone have poor IV lipid solubility and thus are used only orally. The power they lack in IV/IM they make up for orally. For example, oxycodone is slightly more potent than morphine orally (1.5x), but morphine is 2x more potent than oxycodone when injected in any way (IV/IM/SC).

I'd rank the approximate lipid solubility of various opioids this way (top is most lipid soluble and it goes down):

1. Fentanyl
2. Hydromorphone
3. Methadone
4. Oxymorphone
5. Meperidine/pethidine
6. Heroin (morphine prodrug; morphine diacetate)
7. Morphine

Among the highly lipid soluble opioids, morphine has the lowest lipid solubility.

Here is a nice little bit of info.
 
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Hmm, that's interesting, I've always read that buprenorphine was very lipid soluble, yet it's rush is pretty mild. Now I NEED to try IV hydromorphone if the rush is better than oxymorphone (which I thought was way better than heroin)
 
Znegative said:
Hmm, that's interesting, I've always read that buprenorphine was very lipid soluble, yet it's rush is pretty mild. Now I NEED to try IV hydromorphone if the rush is better than oxymorphone (which I thought was way better than heroin)
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I put a ranking, I don't know if you missed that. But believe it or not, methadone is highly lipid soluble and kicks in faster than most opioids if IV'd (but is there a more intense rush? IDK). The thing is with bupe though is that it isn't a full opioid agonist like morphine or hydromorphone are, for example. Also lipid solubility can be an indicator of how intense a rush will be but it isn't necessarily right all the time (it usually is though). What lipid soluble means is that it basically kicks in very, very fast (even if it has no rush).
 
Okay, got ya! I mean, buprenorphine I've heard does produce a nice rush in people that are naive, but I've never experienced it myself. I always found oxy kicked in very quickly when injected, but there was not a rush, just that sensation (what I call a dope taste) in my mouth and nose, and then I'm high.
 
Wow. Thank you SO much!!! You just saved me some serious time and risk....! I really appreciate you both taking the time to explain that to me. And I am totally going to take your advice.
 
Znegative said:
Okay, got ya! I mean, buprenorphine I've heard does produce a nice rush in people that are naive, but I've never experienced it myself. I always found oxy kicked in very quickly when injected, but there was not a rush, just that sensation (what I call a dope taste) in my mouth and nose, and then I'm high.
Click to expand...

Same here. Oxycodone never provided a real "rush" in all my experiences with it. My favorite IV drugs are heroin and morphine because they provide an intense rush and they got legs - the blissful high lasts quite sometime. Hydromorphone is all rush, but no legs. I haven't tried oxymorphone yet. I have IV'd fentanyl and I would say it is the most intense rush of the bunch - but again, no legs to it.

Wow. Thank you SO much!!! You just saved me some serious time and risk....! I really appreciate you both taking the time to explain that to me. And I am totally going to take your advice.
Click to expand...

You're welcome!
 
i get a rush from oxycodone it's not as strong as the rush from heroin or hydromorphone but it's definitely there but the reason the OP probably didn't get a rush the second time is because it was too soon to do another shot only 2 hours
 
Oxycodone has no rush, just immediate onset.... Dilaudid has a rush.... heroin has a rush..... oxymorphone, fentanyl, morphine IV'd have a rush..... Oxycodone, that does not constitute a rush.
 
IV Buprenorphine has an incredible rush w/ no tolerance. However, it can have more than a little delay.
IV methadone provided me w/ little rush.
IV fentanyl was nice, not great. Good nod , tho.
I prefer IV Omorphone to Hmorphone, so I guess I feel it differently.

I think what defines a good rush to me is the combination of fast onset and histamine release (body high)
 
IMO, rush = the amazing feeling that you get as your brain's receptors are flooded with an opiate that can cause a rush, you get the rush because the onset is immediate, but the onset isn't the rush itself. You can get a rush through other ROAs, like rectally, although it is not as pronounced.

OC cannot provide a rush, even in huge doses. I've tried, and failed everytime. Just immediate onset, and a much shorter high than oral oxycodone. Orally is the best way to take oxycodone.
 
lazylazyjoe said:
IV Buprenorphine has an incredible rush w/ no tolerance. However, it can have more than a little delay.
IV methadone provided me w/ little rush.
IV fentanyl was nice, not great. Good nod , tho.
I prefer IV Omorphone to Hmorphone, so I guess I feel it differently.

I think what defines a good rush to me is the combination of fast onset and histamine release (body high)
Click to expand...

Lipid solubility is causes a faster onset. The more lipid soluble, the faster the onset. Fentanyl is the most lipid soluble of the commonly prescribed opioids, followed by hydromorphone and then methadone.

For a fast onset and a good histamine release then your opioids of choice for IV should be morphine/heroin.
 
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