Heroin increasing Heroin's nasal BA via "poppers"/nitrites [vasodialation]

[waldo777]

Theory : snorted cocaine constricts blood vessels in the nose, therefore when Heroin (or any drug) is snorted after a sufficient amount of coke has been snorted, the nasal capillaries, membranes, etc... Cannot absorb the heroin as quickly and or as efficiently as they could have, had no cocaine been used prior..... (I could be wrong, if so please correct me)

Solution : since one probably doesn't want to stop using coke, and wants to avoid the use of needles for obvious health reasons, I have a possible way to counteract the vasoconstriction caused by cocaine......>
----Poppers, AKA: "amyl nitrate", xxx nitrate", etc... Are potent vasodialators, if one were to inhale the vapors of some type of Nitrate-(not a lot! Enough for it to work, but not so much that your in a stupor) and then snort their heroin a few minutes later, waiting enough time to be mostly clear headed but not so long that the effects are gone, WOULDN'T THE HEROIN ABSORB MUCH BETTER DUE TO THE VASODIALATION AND INCREASED BLOOD FLOW????
Using just poppers and heroin I imagine would increase nasal BA, and using the combo w/ cocaine I imagine would @least counteract the vasocontriction back to baseline, if not increase it over baseline...any thoughts????

It should be noted that mixing these drugs can be potentially a very dangerous combo due to the rapid ups and downs and should only be used as a last resort, mainly to avoid shooting up b/c the amounts of heroin that needs to be snorted would be much less than need to be injected. So if you need to sniff a lot of dope, the needle is very attractive, but if there's a way to avoid that, let's figure it out.

Also, I have thought about nitric oxide pills, the ones sold @ vitamin shops for body building. That's b/c nitric oxide and other chems in these products like L-arganine (sp?) are strong vasodialators.
Another thought was to switch the ROA to plugging, but IME I've never had great results plugging heroin. I've only tried a few times, and it could be that what is missing from the high is actually the fact that I/people have some fixation with snorting heroin--the ritual is what's not there, and the BA is equal or better in reality.

I can't say for sure and IDK really, so I'd really just like to consider the use of poppers, and only mention nitric oxide if you have a good argument b/c its long duration of action should be avoided for health reasons

 

[Cane2theLeft]

I don't have much to add but wanted to point out that you're referring to alkyl nitrites and not nitrates.

 

[LawlNub]

Hmm... I've never really had any problems when I used to snort coke and heroin. I even would do zombie dust (Heroin and coke together in one line) and It was great hahah. Sorry I don't have much to contribute to this thread, excepts I've never had any problems with snorting coke and then the heroin not working as well afterwords. But now I'm on the methadone program.

 

[waldo777]

The heroin is being absorbed, I didn't mean that it wasn't working, I just want to safely maximize absorption and thought "poppers" may have been the answer....

Any comments or suggestions are welcomed

 

[dokomo]

Using a vasodilator would increase the speed at which the heroin is absorbed, resulting in a faster onset.

 

[waldo777]

-Dokomo, thanks for the clear and straight-forward answer.
-Cane2theleft, thanks for the clarification, I always get Nitrates mixed up with Nitrites...

So I tried using poppers/x Nitrate before snorting some dope during a day long coke session: after blowing, flushing with saline, and blowing my nose again, I got the dope and straw ready, inhaled some vapors from the bottle of liquid "x" nitrate until I felt my blood pumping, and then snorted as usual:
Sadly, I can't give an informative report..., b/c, 1) was already on coke, dope and benzos, 2) I only snorted my "keep from getting sick" dose, and 3) the head rush/body buzz from the poppers lasted a few mins after I snorted the H--masking any increased effects that may have been present
BUT, that said, I did get a slight burning sensation in my nasal passageway after snorting, and I only get that feeling when I snort with a "virgin" or clean/flushed nose, so there must have been SOME effect on BA.

---what do people think about how much time should pass btwn using the poppers and snorting the H? ---a few seconds, 1 minute, 5 minutes?
Should the poppers be used only before snorting the dope, right afterwards, or before and after?

---what about using nitric oxide and/or L-arganine (sp?) as a vasodilator instead of nitrates?

----are there any other common, OTC, or easily attainable products that are safe and are effective vasodialators?

Thanks in advance

 

[mcgrCONTIN]

Would using a nasal spray such as Afrin or Nasonex increase the intranasal absorbtion of H, considering they open up your sinuses and i know that drugs are mostly absorbed not through the part of your nose you can touch when, say, picking boogers from your nose, but through your sinuses.

Wouldnt it make sense that if you used Afrin or Nasonex your sinuses would be clearer, youd be able to snort better, and the H would be absorbed not neccessarily faster but in a larger quantity (or higher BA)

 

[snooter420]

afrin works great for me and i snort alot of oxy. i seem to get a better high if i use afrin before and after dosing. work for me

 

[dokomo]

Afrin and other oxymetazoline-based nasal sprays are potent vasoconstrictors, and as such, would reduce the amount of opioid absorbed into the bloodstream until the effects wear off. Oxymetazoline is fairly long-acting, so most of the substance would be cleared or sequestered by mucus at this point.

 

[snooter420]

Afrin and other oxymetazoline-based nasal sprays are potent vasoconstrictors, and as such, would reduce the amount of opioid absorbed into the bloodstream until the effects wear off. Oxymetazoline is fairly long-acting, so most of the substance would be cleared or sequestered by mucus at this point.

thanks im glad i havent been using it lately...so ive been doing more damge than good as far as absorbing the most oxycodone possible into my bloodstream....thank you very much for the info.ill stick with putting a little water in my hand and snorting a bit. or is saline the way to go??%)