I have two questions, one has been asked many times, the other I have not been able to find an answer to.
The unknown first- I weigh almost nothing, male 5'9 (175.25 cm) tall and 117 lbs. (53 kg) hydrophobic substances tend to distribute in the brain, as it is very fatty, rather than in the blood. (DMT is a prime example of this) Perhaps a person who weighs 170 lbs and takes a 1 mg/kg dose of something might experience much larger of an effect than a person who weighs 120 and takes the same 1 mg/kg dose because that larger total dose is not distributed equally in the body, but is disproportionately present in the brain, which is generally the same mass for everyone.
A confounding factor may be that someone of a more fatty build might experience less of an effect because the hydrophobic substance may be sequestered in their larger body mass fraction of fat.
Does anyone have any input into the universality of mg/kg doses across individuals of differing body weights?
And the easy question, given a low body mass, what would be an appropriate starting dose of 2C-B, I was thinking of 20 mg. I have had 20 mg of 2C-I and 2C-E on separate occasions, both were quite controllable, although I feel like 25 of either of them in a slightly less controlled environment could have been unsettling.
The unknown first- I weigh almost nothing, male 5'9 (175.25 cm) tall and 117 lbs. (53 kg) hydrophobic substances tend to distribute in the brain, as it is very fatty, rather than in the blood. (DMT is a prime example of this) Perhaps a person who weighs 170 lbs and takes a 1 mg/kg dose of something might experience much larger of an effect than a person who weighs 120 and takes the same 1 mg/kg dose because that larger total dose is not distributed equally in the body, but is disproportionately present in the brain, which is generally the same mass for everyone.
A confounding factor may be that someone of a more fatty build might experience less of an effect because the hydrophobic substance may be sequestered in their larger body mass fraction of fat.
Does anyone have any input into the universality of mg/kg doses across individuals of differing body weights?
And the easy question, given a low body mass, what would be an appropriate starting dose of 2C-B, I was thinking of 20 mg. I have had 20 mg of 2C-I and 2C-E on separate occasions, both were quite controllable, although I feel like 25 of either of them in a slightly less controlled environment could have been unsettling.
