• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe |

I.V. 25I-NBOMe / shooting 25I-NBOMe / 1000mcg

Prescription anti psychotics block dopamine. Do you see the connection?
I can see why this is a bad thing for people who need antipsychotics.
From what I gather LSD works as a D2 receptor agonist. If you're of sound mind then there is nothing inherently dangerous about this... LSD is not known to damage dopamine receptors.
Antipsychotics on the other hand actually kill your dopamine receptors - they are really nasty drugs and if you need to take them then you're too unstable to be dabbling with ANY psychedelics.

You do realize that a lot of antipsychotics (particularly atypicals) block serotonin receptors as well?

Simple as that... LSD has obvious risks that other classic tryptamine compounds barely share.
Possibly, but not in mentally healthy people. LSD's dopaminergic effects are not deleterious.
There are no end of reports out there of people losing their shit and ending up in mental hospitals on tryptamines. DPT is pretty notorious for this and it's not even dopaminergic.

Bottom line is if you have a predisposition to psychosis, if you're mentally ill or if you're on antipsychotic meds then it's not a matter of which psychedelic is the safest... you need to stay the fuck away from ALL of them.
 
I totally agree, this sort of behaviour is just begging for difficulties. Just stick to oral if you must take these chems.

AA357 said:
DPT is pretty notorious for this and it's not even dopaminergic.

Is that right is it?
 
I can see why this is a bad thing for people who need antipsychotics.
From what I gather LSD works as a D2 receptor agonist. If you're of sound mind then there is nothing inherently dangerous about this... LSD is not known to damage dopamine receptors.
Antipsychotics on the other hand actually kill your dopamine receptors - they are really nasty drugs and if you need to take them then you're too unstable to be dabbling with ANY psychedelics.

You do realize that a lot of antipsychotics (particularly atypicals) block serotonin receptors as well?


Possibly, but not in mentally healthy people. LSD's dopaminergic effects are not deleterious.
There are no end of reports out there of people losing their shit and ending up in mental hospitals on tryptamines. DPT is pretty notorious for this and it's not even dopaminergic.

Bottom line is if you have a predisposition to psychosis, if you're mentally ill or if you're on antipsychotic meds then it's not a matter of which psychedelic is the safest... you need to stay the fuck away from ALL of them.
I completely agree with you and thank you for pointing out what atyplical antipsychotics are as I have not looked into them.

My point is just to be aware of the damage that can be caused and what may need to be needed to reverse it. No one needs one thing or another. Apparently the homeopathic philosophy is we all have the inner strength we need and we use medicines in small amount to boost that strength wae are born with and not to rely on the strength of what we take in. No one needs these compounds, but they can be useful.

I don't think it's safe to say for one other person whether or not they should trip, but that does not mean to not voice concerns. It just means only one can decide for oneself based on their understanding of their own strength and faith in one's own strength. You are right as well though at some point in most lives unfortunately all of life for some not everyone can gain the strength at time of life to go through the experience.

Still that is something one needs to decide for oneself and not based on generic groups especially ones as bad as our mental hang system being completely over anylitical. Did you see the "news" saying putin possibly has aspergers....

I mean really because in tense situations he is quick to jump to fight or flight response? Did they do fucking brain scans to confirm these major claims? It's truly offensive to those that may struggle with the issue, which could be a huge developmental factor their strict somewhat struggling economy could easily lead to. See the difference in wording? Mines a hypothesis with no evidence, but in my opinion sounds viable. They state hypothesis as baseless fact.

Didn't read this article it just looked like best title vs cnn and yahoo
http://www.theguardian.com/science/...ty-of-psychological-diagnosis-from-a-distance

Anyways I'm off topic time for me to duck out

Edit: I would like to see stories on dpt of what you are mentioning. I remember people at the dmt nexus trying to vape huge amounts that just didn't sound worth it. I'm realizing some doors do not need to be opened and I'm glad I did not open too many at a young age. It's like yugioh and the Millennium puzzle. I'd explain that one, but I'm too lazy to find the right words now.
 
Last edited:
Dig deeper. People have experienced fairly serious adverse reactions at recreational doses, while others have reportedly been fine on considerably heroic doses.

What would you rather take from that - NBOMe compounds can be safe in high doses, or NBOMe compounds can be potentially dangerous in normal doses?

IMO, if you'd rather believe (and god forbid spread) the former, you're participating in the wrong community forum and should not be posting such things as they don't fall within HR ideals. Fear mongering as you put it however does, even if it's overkill.


The same is 100% true of MDMA. There are cases, although rare of a person consuming a single pill and having some serious shit go down or yes even death. Call it an allergic reaction, call it dehydration, call it the symptom where a person can't take a piss and the kidneys shut down and you poision yourself. MDMA is quite a bit more expensize when compared to Nbome's though, and the dose response curve isn't as potentially frightening. Still though MDMA is not like LSD where we can say you definitely won't die from 10 hits. 10 hits of MDMA can kill a man last time I checked. If a person survived 10 hits of MDMA it probably would not be a good time.


I would not recommend anyone to IV or IM anything, that was my first point. I have heard that a person can IM or IV MDMA, but I would never recommend it.
 
this is the most bizarre forum thread I have ever been involved with,
probably because it could be the most dangerous idea - it can go from idea to death is a few seconds -
especially in the wake of many underdocumented tragedies following attempts of people to experiment with this class of psycho active amphetamine.

however, a pharmaceutical preparation of 250micrograms could be a very pleasant strong experience
administered via this route.

I would not attempt it unless administered in a hospital or next to a well equipped medical station.
 
Is that right is it?
Do your research... DPT doesn't have the dopaminergic activity of LSD.

I completely agree with you and thank you for pointing out what atyplical antipsychotics are as I have not looked into them.
No problem. Psychosis is a very complex condition.

My point is just to be aware of the damage that can be caused and what may need to be needed to reverse it.
Definitely. It pisses me off when people take drugs without knowing or caring about how they work.

Your theory that LSD might be more dangerous for the mentally ill than tryptamines makes perfect sense and probably does hold true... it's something I'd never thought about TBH.

That said, there is no evidence that the dopaminergic component poses any sort of risk to people who are of sound mental health. LSD is probably the most well-researched psychedelic in the world, so I really wouldn't worry about it.

Edit: I would like to see stories on dpt of what you are mentioning. I remember people at the dmt nexus trying to vape huge amounts that just didn't sound worth it. I'm realizing some doors do not need to be opened and I'm glad I did not open too many at a young age. It's like yugioh and the Millennium puzzle. I'd explain that one, but I'm too lazy to find the right words now.
There are quite a few reports of hospital trips on high-dose DPT on Erowid experiences and on forums. It hits you DAMN hard and tends to make people think they're dying... this has caused a lot of freakouts.

This is about the most fucked up trip report I've ever read:
http://www.hipforums.com/forum/topic/379629-dpt-200mg-smoked-dmthopefully/
 
I was questioning your allegation about the notoriety of DPT. Ime, this is a largely unsubstantiated claim not really backed up by anything. Anecdotally, I've never considered DPT to be more disorienting then other psychedelics, and my own use of it, which has been at least 30 times, has never really lead to anything more then profound trip..

I'm aware that DPT is not dopaminergic...
 
Last edited:
Top