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Benzos I.M. ativan BURNS LIKE HELL!

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dogshark2001

Greenlighter
Joined
Jan 20, 2010
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2
Friend of a friend has access to lots of lorazepam 1ml vials (2mg/ml). Stuff is thick but when my friend tried to inject he said he could not because it burned so badly. How do they inject this stuff intravenously? He could not bare to inject even 1/2 ml...not even 1/4 ml intramuscular because it burned so badly.

Can he inject lidocaine with it? He tried saline but it took 1ml of saline with 1ml of lorazepam to keep it from burning too badly, but 2ml is a LOT to inject via I.M.

I.V. is a not go, any ideas?
 
I was always under the impression that lorazepam wasn't water-soluble. Maybe that preparation is...well, I guess it would have to be unless the lorazepam is dissolved in something else....maybe that's what's causing the horrible burn.

My experience with ativan...just eat the damn stuff, or drink it in your case. :\
 
could you list what the exact contents of these vials are?

if they're a thick solution i'm thinking they're maybe an oral solution? or the solution needs to be diluted down quite considerably if it is to be injected intraveneously or muscularly.

i'd definitely refrain from injecting anymore until you know what you're dealing with.
 
If you're IM'ing it you need to push the plunger very very very slowly. And try to use a 32 or 31 gauge rigs (1ml). Use the buttocks, its the best place to IM, a 1ml should take thirty seconds.

I advice against your idea entirely for safety sake. Eat the ativan, it'll add some years to your ife. Unless of course you have micron filter and a lueir lock syringe (yeah neither do i), if you did you could bang that Ativan.

You sound like you could benefit
 
^They're vials apparently meant for injection.. well maybe, it seems like they may not be.

Did you think he said pills? Seems like that's what you're talking about.
 
^even with micron filtration, its not a good idea to IM pills.

I know this thread is about vials, just wanted to toss that in.
 
I'm all little drunk, excuse my miss-information. What I mean was that if he had a micron filter he could get away with IV'ing. Even though I still think its pointless. The only thing I'll IM is a Ketamine Vial.

gotta love medically sealed vials
 
skoat said:
If you're IM'ing it you need to push the plunger very very very slowly. And try to use a 32 or 31 gauge rigs (1ml). Use the buttocks, its the best place to IM, a 1ml should take thirty seconds.

I advice against your idea entirely for safety sake. Eat the ativan, it'll add some years to your ife. Unless of course you have micron filter and a lueir lock syringe (yeah neither do i), if you did you could bang that Ativan.

You sound like you could benefit
Click to expand...

This is also correct. When I have IM'd Ketamine (and 2c-E) in the past, so little water was used that it was extremely efficient, even if I still pressed the plunger slowly.

Skoat; they have ativan in a vial with solvents already; lorazepam is very slightly soluble in water (not good enough to make use of tablets unless you have other solvents or are super-fuck-sensitive to ultra-low doses of benzos).

At 0.08mg/ml, that's almost piss-poor solubility.

Cane2theLeft said:
^even with micron filtration, its not a good idea to IM pills.

I know this thread is about vials, just wanted to toss that in.
Click to expand...

Ideally, you would want to examine all inactive ingredients, and their ability to be filtered out with a certain pore size or not, whether they are water soluble or not, etc.

For people who are going to IV anyways, micron filtering (using bacteriostatic water) with a 0.22um layer is a lot safer than anything else.

Furthermore, sometimes the pH won't be correct, hence injecting (Atarax, for instance) pills after micron filtering still poses a potential danger (due to a low or high pH).

skoat said:
I'm all little drunk, excuse my miss-information. What I mean was that if he had a micron filter he could get away with IV'ing. Even though I still think its pointless. The only thing I'll IM is a Ketamine Vial.

gotta love medically sealed vials
Click to expand...

1mg of lorazepam would need 12.5 mL of just water if you don't have any other solvents, so it wouldn't be all that efficient.
 
Last edited:
He (she) is talking about injectable vials....those made for sc, im or iv administration in a medical environment. YES, Ativan is very thick and irritating to inject in any way due to the thickness. When administering it to pts...for IV, I usually dilute it with about 1cc saline...but youre also talking about it being being given thru an actual indwelling IV site...not someone trying to hit a vein and maintain the position while injecting stuff that requires some serious manpower behind pushing that plunger.

To give it IM, unfortunately, there is no way around the burn. It is a very uncomfortable med to get via injection.
 
Sounds like your best [read: least painful] bet is going to be just using it orally.

I believe Ativan has a very high oral bioavailability much like other benzos.
 
Like happygolucky said, you really need the hospital equipment if you want to IV without much problem. IT definitely needs to be diluted and even so, IM is still going to hurt. Oral BA is high and onset is quick, so I dont see the real need to IV.

I have had IV Lorazepam many many times in the hospital and there is no rush to it if thats what you are looking for. It is just a calm that you would get orally, only it comes on quicker by about 15-20minutes or so...
 
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