LucidSDreamr
Bluelighter
nichols has a review commenting on some work such as this. they made thiobenzofurans of dmt as well and they were agonists at 5ht receptors but not as good as dmt, serotonin, etc. so yea they still work.
N&PD Moderators: Skorpio | someguyontheinternet
No, your right. If you change anything else, it won't be a Lysergamide anymore, and probably won't be active. (Well, both the tryptamine and phenethylamine skeleton is inside of there, so I guess it's not completely impossible, but it won't really be a LSD analog anymore)Is it just me or do most LSD analogues only change stuff at one of the nitrogen atoms?
Is it just me or do most LSD analogues only change stuff at one of the nitrogen atoms?
Or how about bk-5-mapb and bk-6-mapb:
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With the key exception of mephedrone, has the addition of a beta-ketone ever improved the effects-profile of a recreational drug?*
I don't know if improved is the right word, but adding the beta-ketone to 2c-b preserved most of the good effects while extending duration.With the key exception of mephedrone, has the addition of a beta-ketone ever improved the effects-profile of a recreational drug?* You might be on to something though, insofar as making the APB series less serotonergically selective might hold promise. However, the serotonergic selectivity of these compounds is as of yet up in the air (the one study showing 6apb to lack significant affinity for SERT requires replication, as they got weird results for some of their 'control' compounds, and other studies have found 6apdb and 5apdb to be more serotonergically selective than MDMA).
*I have seen only scattered reports of 4-Me-MA, and 4-Me-A might well be pretty damn fun, but it also appears to be hideously neurotoxic, somewhere between a longer acting MDMA and PCA.
ebola