I just successfully did it with no pain or discomfort. I used a 25g needle with 10ml syringe and i diulted about 30-40 mg in 6ml of water. Like i said no discomfort. I had already sipped about 40mg and i was feeling quite well but now I am nodding off as I right this reply haha. I am not on methadone maintenance and I dont plan on making this a regular thing, I just so happened to score these two bottles of liquid methadone. Im more than positive that the ingredients found within this liquid methadone is NOT suitable for my veins. So my overall reccomendation to the public is to give it a try but make sure to dilute the methadone, BUT dont make this a regular thing!!!!!