I can debate -- DXM

[psood0nym]

Opiates: Opioid Receptors
Cannabis: Cannabinoid Receptors
DXM: ???

... DXM is dirty. Heroin is clean. Certain drugs have developed a symbiosis with humans, due to continual use throughout history. The natural drugs. The ones we are "meant" to consume.

The drugs are designed for us by God.

No offence to Shulgin, but he ain't God.

Meet Acacia berlandieri, whose ALL NATURAL GOD GIVEN constituents have been found to include:

A. berlandieri contains a number of diverse alkaloids, the most plentiful of which are N-methylphenethylamine, tyramine, and phenethylamine. In a recent study, researchers identified thirty-one alkaloids in samples of plant foliage, including trace amounts of five amphetamines previously believed to be human inventions:[5] amphetamine, methamphetamine, N,N-dimethylamphetamine, p-hydroxyamphetamine and p-methoxyamphetamine. Other trace alkaloids include DMT (found in many related species), nicotine, and mescaline (found in many cacti but infrequently in other plants).

I guess God intended us to be paranoid sweaty half-dead meth heads.

 

[choco1ate]

how about not doing dxm, meth or h because theyre all bad..

@op are you doing powder or syrop? just curious

 

[ForEverAfter]

Meet Acacia berlandieri, whose ALL NATURAL GOD GIVEN constituents have been found to include:

I didn't say all plants were meant for consumption. Obviously, there are many natural poisons.

Dextromethorphan (dxm) is a semisynthetic opiate in the morphinian class, so a pretty standard opioid actually... one with very odd properties. DXM is not a phenethylamine like 2C-B, Mescaline, Amphetamine, MDMA, etc. DXM has a long pharmacological history

There is relatively limited information, and study, into the long term effects of DXM abuse; in comparison to, say, heroin. Although it has been used as a recreational drug for some decades, it has not been used for as long as - say - heroin. As for it being a "standard opioid with very odd properties"... I was under the impression that various synthetic and semi-synthetic opioids were highly neurotoxic. Whereas opium (H) is not...

 

[psood0nym]

^OK, well there are opioids that react with other receptor systems like tramadol. Yes that's synthetic. But do you really think it would take long to find a natural cannabinoid or opiate that isn't "clean" in the way it reacts with the human brain?

 

[Edvard Munch]

sonicwhite states something that is undefinable and unsubstantiated in claims, seemingly follows the logic of someone in whom does drugs.

 

[ForEverAfter]

OK, well there are opioids that react with other receptor systems like tramadol. Yes that's synthetic. But do you really think it would take long to find a natural cannabinoid or opiate that isn't "clean" in the way it reacts with the human brain?

I don't see the point in playing God with chemicals. There are more than enough natural drugs for a lifetime. The world would be better off if there were no chemicals. Opium, instead of H. Ayahuasca, instead of DMT. Drugs are dangerous enough in the first place. Chemical drugs increase the potential for harm massively. I have collapsed veins shooting meth. If meth didn't exist in the first place, I wouldn't have done that. And I would have been quite happy with the shamanistic equivalent. Overdoses are often the result of misjudging tiny amounts of super potent chemicals. It's practically impossible to consume too much mescaline cacti juice. Or too many mushrooms. Most of the mainstream natural drugs, are relatively safe. You can easily overdose with opium. But not as easily as you can with heroin. Putting chemicals up your nose and in your veins. Taking C3P0 and 4-Methoxy-Butyl-Atropine. Taking THX1138 and 2-73-N-Dimethyl-Corazone. Taking drugs less than five years after they're invented is fucking crazy. Playing God with chemicals, means we'll develop a drug - eventually - so perfect and void of consequences that everyone will become addicts. And that's not a good thing. The problem with ecstasy, in comparison to LSD, is that it makes you happy artificially rather than getting you to ask the question. Am I happy? The pain of the psychedelic experience. The bad trip, that people try to delay or ignore or demonize. When people develop the perfect tailor made drug, there won't be any bad trips. Just pure consequence free bliss. And that's not what we need. I don't believe in playing God with chemicals, because drugs are holy; man-made designer-drugs are sacrilegious.

edit: I misread your question. Yes I'm sure there is quite possible a poisonous (or highly neurotoxic) natural cannabinoid. Again, I didn't say all plants were meant for consumption.

 

[bennyZA]

I don't see the point in playing God with chemicals. There are more than enough natural drugs for a lifetime. The world would be better off if there were no chemicals. Opium, instead of H. Ayahuasca, instead of DMT. Drugs are dangerous enough in the first place. Chemical drugs increase the potential for harm massively.

Yea man, with my experience's as well, I couldn't agree more. However, to each his own. I'm not here to judge.

 

[Thorns Have Roses]

Yeah, so there hasn't actually been anything of substance said against DXM said in this whole thread. No one is disagreeing that it can be addictive, and that abusing dissociatives has deleterious effects on one's health. If you guys want to read something about problems possibly caused by DXM use, consider reading this thread:http://www.bluelight.ru/vb/threads/367073-DXM-Subthread-Long-term-DXM-Effects-on-the-Body-Mind-Behavior.

Opiates: Opioid Receptors
Cannabis: Cannabinoid Receptors
DXM: ???

DXM (and we're counting it's primary metabolite DXO too): NMDA receptor antagonist
Also a sigma receptor agonist, serotonin and norepinephrine reuptake inhibitor, nicotinic acetylcholine receptor antagonist, and other things.


Oh and based off the last couple of posts, this thread may interest some of you: http://www.bluelight.ru/vb/threads/129327-The-Main-Natural-vs-Chemical-Synthetic-Psychedelics-Thread