Well, just with ayawaska you got 10-20 different spieces you can put in it, so its hundred of different "drugs" you'll have to try.
Have a nice pucking year
Not really, they all contain DMT. The main difference is which MAO inhibitor you use as some cause the classic nasty purging while others are quite forgiving and easy on the body.
Plus, Ayahuasca is not a research chemical, it is a brew that contains the illegal DMT - which we know a lot more about than even some of the oldest research chemicals.
I think "trying every research chemical" is a bit broad as even finding sources for say 5% of the research chemicals out there would most likely take a life-time, nevermind taking them all. You have to factor in tolerance, costs, potential dangers, etc.
However, on the other hand, you could come up with a list of say 30 different RCs you really want to try, and try them all. Just make sure you research the chemicals thoroughly before taking them and ensure that your source/s is/are legitimate (ideally test your RCs yourself to ensure they are what you've been told they are), use them safely and you should have a great time ahead of you.
If you must try as many as possible, my advice is to set a short 5-10 chemical list and complete that before you move on, for example you could start by doing as many 2C-*'s as possible, then some tryptamines, etc. However, like I said, make sure you research each chemical thoroughly before even considering trying it.