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Opioids Hydrocodone vs Tramadol

PurpmanZ

Greenlighter
Joined
Apr 10, 2013
Messages
2
I have been a frequent user of lortabs over the past few year and my connect aren't able to get anymore for me until a month or so... All they have is Tramadol and I got some. and I'm wondering if I normally have to take 40 mgs of hydrocodone just to feel a little buzz what would be a good amount of Tramadol to take that you would see as equal to that amount and not to go over the amount of 80 mgs of hydrocodone seeing as that make me feel like the high is too much.
 
That google search didnt show anytging about tramadol on any of those tables my friend
 
Sorry bro, i was honestly way baked earlier. And now, but that's the story you know?

Anyway ha, you're totally right... i was honestly mimicking the rookie countenance weren't I? The 5 charts i looked at were outdated, and this iphone won't load much more. Didn't wanna get off on the wrong foot, i'm not that kind of person.

I meant the whole friend business, it just seemed like it wasn't answering their question fully. And to a lazy person it would seem so.

Yeah... :))<~'''
 
Tramadol's better than nothing, but most people can't metabolize enough O-Desmethyltramadol from tramadol due to CYP2D6 deficiencies, making it a useless opioid prodrug. Others have regular amount of 2D6 liver enzyme alleles, so tramadol is simply a weak prodrug for them.

On the other hand, a small minority have so many copies of the 2D6 enzyme alleles, like me, so tramadol is a much more powerful prodrug. In my case, 50mg of tramadol is stronger than 12.5mg of hydrocodone once the O-DT starts kicking in 2-3 hours after tramadol ingestion.

I would pick em up for really cheap from him if I were you, since they're unscheduled and readily prescribed. Remember to never take more than 150-200mg at a time, and never more than 250mg in a day. If you want to cut down on the stimulant effect from the tramadol, and just want the opioid effects from the O-DT metabolite, then take a 100mg starting dose, and dose 25mg (half a tab) every 20 minutes until you reach 200-250mg/day.
 
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