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  • BDD Moderators: Keif’ Richards | negrogesic

Hydrocodone and flexeril?

S

Stonedface

Bluelighter
Joined
Jan 25, 2011
Messages
94
I'm going to be taking 17.5mg of hydrocodone and want to potentiate it so I'm just lookin for some suggestions. (I did try googling this so sorry I gatta make a new thread, just want some direct answers). 2 days ago I did 15mg and felt good but today did 15mg and did not feel as euphoric as the first time. So for my last 17.5 mg of my hydro I have left, I want to get the most out of it.
I have 10mg flexril and was thinking 10-15mg to go with it would be a good dose but want to ask you guys if that's a right dose. I've looked up the flexeril pill but it doesn't say wether or not it's time realase but its yellow and the inside is white so should I crush these?
Another thing is I have 100% white grapefruit juice too and kinda found mixed things sayin it does potentiate effects of hydro and also read somewhere it reduces effects. The thing is this morning an hour before I popped my 15mg I drank a cup of it and like I said I did not get as much euphoria today as I did the first time. It's weird cause I didn't think tolerance happned that fast.
So any suggestions on the GF juice and flexeril would be much appreciated.
Oh btw these are the first times I've done opiates since about 3 4 months. Before like 30mg of hydro would be satisying and like half a Roxie would do the trick for me since I last did opiates if that helps.
 
My experience with flexeril showed me that flexeril isnt much on its own. However, the one time I combined it with methadone, lets just say I fell asleep on the busride home, passed my stop by a LONG way. When I woke up I realized I missed my stop, but I was plenty coherent and capable of getting off the bus and getting on another going back the way I needed to go. Point of telling you this is that flexeril on its own, I took it several times by itself, just didn't do a whole lot-but when I combined it with an opiate (methadone) i passed the fuck out- and my methadone dose was my prescibed dose that would not have made me sleepy, and the flexiril dose was quite low-i dont remember the dosage of the pill (this was years ago) but I do remember it was only one pill, so the flexeril on its own also would not have put me to sleep. This leads me to believe that flexeril DOES potentiate at LEAST methadone. Hydrocodone is obviously an opiate as well, so you might have some potentiation with the combo. Also, my experience with combining the two showed me that there was no increase in euphoria (methadone isnt exactly a euphoric drug anyway, nor is flexeril) it just made me really sleepy. Being that methadone is very different from hydrocodone the result might be quite different. Based on my experience, I would keep your flexeril dose at probably 5mg and see how that works, go from there. Just be careful, and please wait for more responses as somebody may be aware of some dangers with this combo that I am not aware of. Please keep your dose of flexeril low, but I think 17.5 on the hydro should be an ok dose, since you've taken that much before already. Please wait to hear advice from other people before taking this combo.
 
Here's a good rule of thumb for combining stuff with hydrocodone (or other opiates) - take whatever you are adding by itself. If it has no noticeable effect or a slight effect on you then that is the dose you want. If it has a moderate or strong effect on you then it's too much. Any decent potentiator doesn't require very much to get the desired effect when added to hydro. Never tried Flexeril but would recommend starting with half of whatever the "therapeutic dosage" is (dose recommended as a muscle relaxer by doctors).

Also, I always drink a tall glass of white grapefruit juice about 45 min - 1 h beforehand. Not the same thing as a potentiator, it just slows the liver metabolism of hydro
 
^I would think that white grapefruit juice would make it absorb quicker thus not lasting as long.

I don't know as far as combining those two but you should wait like 4 days to take hydrocodone again regardless because of your tolerance. Yes, it does raise that quickly. To feel like you did with that 15mgs you would need to wait a few days and take 15-17.5mgs. If your just waiting a day or two you'd need like 22.5mgs
 
White grapefruit juice is a potentiator - it's a true potentiator in that it affects the metabolism of the drug causing it to remain in the body for longer, rather than something like a benzo which just adds to the sedation.

If the drug is active, and it's metabolites are inactive, then inhibiting it's metabolism will potentiate the effects. If it is inactive (a pro-drug) but it's metabolites are active then inhibiting it's metabolism will decrease the effects. If it is a mixture.. then it depends on the individual drug.

Hydrocodone is active, but it also has at least one active metabolite (hydromorphone) but I don't think hydromorphone plays a significant role in the opioid effects of hydrocodone - so overall GFJ probably would potentiate it. I am not entirely sure about this however, never tried it myself as we don't have hydrocodone in the UK!

I don't know about Flexeril I'm afraid, but as a muscle relaxant it could add to the overall sedative/relaxing feel.
 
Flexeril isnt a muscle relaxant that isnt anything worthwhile taking imo...........if you can get Soma, take that with hydrocodone, its a great mix. Only thing Flexeril does is get you super tired & groggy, a terrible pill imo.
 
Flexeril will just dirty up your high. Just take the hydrocodone alone. Throw the Flex in the garbage unless you use it to get to sleep.
 
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