I have some more interesting research and a theory not currently discussed in this thread.
Why can a pill contain MDMA only but some can be rushey, some mellow, some dancey. ie defqons/speakers/triforce etc. This is confirmed by user reports and lab reports. It is not speculation.
Many have confirmed some MDMA only pills are just different.
And all these pills discussed contain only one active ingridient MDMA. HOW & WHY???
I was looking at a thread on bluelight where people were discussing the theoretical concept of MDMA purity.
MDMA is it 84% pure or 100% pure?
Quote from Vader bluelight that summarises the cause of debate.
The number refers to the proportion of the sample constituted by MDMA molecules. In MDMA HCl, there is one molecule of HCl (with a relative mass of 36.5) for every molecule of MDMA (with a relative mass of 193.25), and so if the salt is totally pure, 84% of it is MDMA.
The debate is formed around the idea that when MDMA is in a liquid form (MDMA Freebase) (which you cannot drink) it needs to be mixed with an acid to form a bond thus forming into a salt. In the case of MDMA it is usually Hydrochloride or better known as MDMA HCL.
Thus with the salt molecule its not pure right? The argument is academic really and not the point in here BUT it got me thinking....
I thought more about george WCs comments about Concentration. I then looked more into the Freebase of MDMA.
MDMA in its basic form (Freebase) (Definition below)
The natural form of a drug, hasn't been reacted with an acid.
You can change it back and forth between its freebase and salt form as many times as you want.
Now I have been reading some discussions on a Bee (synth) site where there are discussions about MDMA and it doesnt have to be HCL!!
Hydrochloride
http://en.wikipedia.org/wiki/Hydrochloride
It could take some other forms very easily by just bonding with the relevant acid:
Tartrate
http://en.wikipedia.org/wiki/Tartrate
Phosphate
http://en.wikipedia.org/wiki/Phosphate
Citrate
http://en.wikipedia.org/wiki/Citrate
Sulfate
http://en.wikipedia.org/wiki/Sulfate
I picked up this comment from a Bee it was a theoretical discussion:
-Tartrates:are known on some underground sites as "twice as potent" than mda hcl salts,because that great absortion potencial by body...but seems nobody talk about that.
comment on a sciencemadness site
It more then likely boils down to physical properties of the various salts. In some cases the HCl salt is hygroscopic so some pharmacuticals opt for the sulfate salt. Other times it boils down to absorbtion. Take for instance the illegal compound MDMA whos citrate salt manages to get degraded in a different part of the gut then the HCl salt allowing for more complete absorbtion into the body before it is metabolised.
So based on previous discussions I think we all agree that seperating out isomers (although very possible) is not practical, you will lose some product, you then according to shulgin dont have the magic, to make the magic so you would have to mix it with some racemic MDMA. A total pain in the ass no clan lab will do this.
BUT..
To make different salts of MDMA. This is very possible. All you do at the point of freebase is bond the particular acid for the salt required.
Very easy to select a certain buzz for a certain batch. No extra hassle only a different acid required.
My other thought is MDMA HCl is the desired salt for Molly powder. probably because the crystals look nice and its easy to handle. But this could explain why crystal HCl is always so mellow.
if you make a sulphate, or a citrate or a phosphate it might not look so nice but if its going into a pill mix who cares.
Just a thought but a very likely possibility.
Unfortunately theres not a lot of info out there about it but based on government confiscation reports etc other salt forms certainly exist. The concept is real.
Theoretically if you had some MDMA powder it would not be very difficult to turn the MDMA back into a freebase and then turn it into a different salt. Someone with very basic chemistry understanding could perform this task.
I cannot find any reports anywhere about the different effects of the different salts. Perhaps this is the secret we have been searching for??
Any comments or extra thoughts massively appreciated.
Evidence of these other salts actually existing:
http://www.ncbi.nlm.nih.gov/pubmed/14640267
The finding of the phosphate salt of MDMA is intriguing. Based on a presumptive color test, spectroscopic data (FTIR/ESI-MS) and the percentage of MDMA content in a purified phosphate salt of MDMA, the ratio of the phosphate to MDMA was determined to be 1:1, suggesting that the compound is a dihydrogen phosphate salt [i.e. (HMDMA)H2PO4].
http://www.emcdda.europa.eu/publications/drug-profiles/mdma
The most common salt is the hydrochloride (CAS-64057-70-1) which occurs as a white or off-white powder or as crystals soluble in water. The phosphate salt is also encountered. Illicit products are seen principally as white tablets with a characteristic impression (logo), less commonly as white powders or capsules. MDMA base is a colourless oil insoluble in water.
http://homepages.ihug.co.nz/~Smconnell/MDMA pill profiling.pdf
This extract shows a phosphate based pill in their samples. Not for the light hearted but loads of info about pills generally.
Further interesting research extracts info below:
the thing that i find interesting to read about is the possibility of changing the absorption rate by using different salt forms, the purpose being to increase mdma's peak to something similar to mda's peak. this is very interesting to read because then perhaps instead of double/tripling the initial dose (to reach those more intense/longer peaks) or re-upping later on (to extend the peak), perhaps one could dose their regular dose of mdma hcl but also mix in a specifically selected salt form that will take much longer for your body to absorb it. say your normal dose of mdma hcl plus another dose or half dose of mdma sulfate or some such. that way the mdma hcl hits immediately and provides the experience, then throughout the experience the secondary salt form is slowly ingested throughout the mdma hcl experience effectively given a more intense experience (although certainly not as intense as just dropping a whole lot of mdma, but again the purpose being to provide a ~8 hour mdma experience would be preferable) and longer peak... all the while ingesting a little less, say 200mg (100mg hcl, 100mg other salt) instead of 400mg etc to reach a similar effect.
method for MDMA citrate (Its possible!)
1 mole of mdma reacts with 1/2 mole of citric acid mdma(II)citrate.
mdma ethanol stoichiometric citric acid and diethyl ether work the best the problem with mdma citrate is it tends to suck up water and it's hard to crystallize it turns gummy.
so mix the mdma with alcohol and citric acid then take the alcohol off under vacum and dry it under vacum/heat to a constant weight.
then, procedd to recrystallize.
azetropic distillation should also work .
petro ether works as a nonpolar recrystallization solvent also.
i don't know how i knew that, a little bird told me.
"There're alot of drugs when put into a different salt form are metabolized quicker crossing blood brain barriers. Kinda like what the diactyl on morphine does to your brain. "