i've never noticed 5-meo-mipt to be toxic.
then again i only ever took it orally once and i thought it was awful vs smoked.
15mg orally was electric and jittery and my heart was just pounding in my head but not in my torso. it really isn't all that pleasant orally i've found. The body buzz kind of assures you of that.
now 15mg smoked is awesome, just put a pinch on top of a bowl of weed and you can either smoke it all at once and achieve the Moxy Breakthrough, which is pretty spectacular in its own right. I've experienced the entire tree line of my back yard turn into a giant face. the wind would blow and make the leaves look like hair and stuff. It was really really awesome.
or you could smoke it slowly through an afternoon to achieve a steady headstrong euphoria.