^More bang for your buck (sometime twice as much), no drip/less burn, often less nausea, and in the case of mescaline or aMT, shorter onset and overall time you need to commit to the trip. No obsession needed, just rationality and comfort with your sexuality/body. I do support your suggestion to refine any extraction down to a relatively pure crystaline product, though. I can't remember the thread exactly, but I remember one guy trying to put a relatively slime free boiled down water extract up his ass and he ended up vacating it within 30 minutes doubled over in pain. The stuff in cactus besides mescaline must be irritating to digestive tissues (especially when it sits in one tight spot for a long time). I know even when I use ondansetron to avoid mescaline nausea from cacti if I don't get too nauseated I still vomit from the burning pain of cactus alkaloids sitting in my stomach (ondansetron just lets me keep it down long enough to work). If you do make a crystalline product, put it in solution and check the pH before sticking it up there though, since some of the chems you used to extract it may be mixed in with the final product.