Hi there,
We need to know what sort of oxycodone your friend has (is it really your friend or you? If you, please say so). It's going to be ER if it's Oxycontin - the big question is whether it is the old OC formulation or the new OP formulation. If it's an IR oxycodone then you don't need to worry about the time release obviously.
If it's the new OP ocycontin then don't IV it. Breaking the time release is very hard (see
*here*) and the end product would not be safe to IV under any circumstances.
If it's an OC or an IR oxycodone.. then it is possible, although I still strongly advise against it. Shooting pills is dangerous - on top of the
normal IV dangers there is a risk of developing a severe and progressive lung condition called talcosis/pneumoconiosis, a high risk of abscesses if you miss and a higher risk of vein damage.
It is essential that you use a
micron filter and
don't cook/heat the pill (this causes nasty poorly soluble particles to dissolve and enter your shot; oxycodone is freely soluble in cold water so there is no need).
Oxycodone has a very high oral bioavailability, and most people don't get a rush from shooting it, so there is very little benefit in IVing it - at much greater risk.