How to get high off of Oxycodone.

[Dnicolle4]

Ok so I'm wondering it you guys can help me. I'm trying to get high off of some Oxycodone I have. It's says 5-325MG. I'm new to this, it was given to me for my pain with my surgery and it worked great! The first two times. I had to take two and I would really comfy and happy and had a nice buzz going on. But that only lasted twice. Now when I take two does nothing, doesn't even help with the pain I get sometimes. I'm wondering should I up it up to 3 or maybe 4? I'm worried about the APAP though. I'm really new to all this but I just need to get over this day.

 

[pasha]

you took two and it did the trick. that's 10 milligrams of oxycodone and a good starting dose (the part that says the 5 and 5 x 2...).

you can kick it up to 15 (3 pills) to 20 milligrams (4 pills) with no problem. always escalate your dose slowly and monitor your tolerance as you have been doing. you can ignore the apap (the part that says 325) until you reach 2,000 milligrams. that's about 6-7 pills. this is speaking hypothetically, if you do reach that stage.

also look into milk thistle when you take oxycodone. it protects the liver from toxins and cirrhosis. also look into liv 52. as an added bonus, milk thistle supposedly inhibits the enzyme that metabolises oxycodone by 50%.

Milk thistle extract is one of the most commonly used nontraditional therapies, particularly in Germany. Milk thistle is known to contain a number of flavonolignans. We evaluated the effect of silymarin, on the activity of various hepatic drug-metabolizing enzymes in human hepatocyte cultures. Treatment with silymarin (0.1 and 0.25 mM) significantly reduced the activity of CYP3A4 enzyme (by 50 and 100%, respectively) as determined by the formation of 6-beta-hydroxy testosterone and the activity of uridine diphosphoglucuronosyl transferase (UGT1A6/9) (by 65 and 100%, respectively) as measured by the formation of 4-methylumbelliferone glucuronide.

http://www.ncbi.nlm.nih.gov/pubmed/11038151

edit: forget about the milk thistle. because it's dangerous when used with apap as it also interferes with its metabolism which can cause more hepatoxicity. liv 52 (a mixture of herbs used for liver disorders) is your best option for a hepaprotective antioxidant agent that does not interfere with either oxycodone nor paracetamol metabolism.

 

[J3MOd-h3NOW-X3S]

Well if two doesn't give you a buzz, go to three.. Also chew them instead of swallowing them whole. So chew 3, wait an hour or two ( That's about how long it takes to fully feel the effects, give or take, it's specific to the person, but that's ballpark..), re-dose 10mg every hour or two until you reach desired effects. The daily limit for APAP is 3-4g, so 9-12 of the 5/325's.. Also if you're worried about the APAP, you can do a cold water extraction (CWE). The oxycodone dissolves into the water before the APAP does, so you just strain the APAP out, and drink your oxycodone water. This process is quite simple and quick. There's a shit ton of "how to" CWE threads on this and many other websites... Just type CWE into the search bar.

 

[downerhead]

When taking percs or the like,I've had good results crushing them up and taking them like a BC powder.This helps them dissolve faster and thus hit you harder.Washing them down with hot liquids like a cup of coffee helps this out even more.

 

[OxyDevil]

10mg of oxycodone is a good dose to start with, but in a very short time you need at least to double this dose to reach the same effects.... unfortunately the pills you got have the paracetamol and you are unbable to snort it(well you can, but sounds bad for me)..if you had pure oxycodone tablets like the old oxycontins , you would be able to crush and snort , say, 10 mg , and eat another 10 for a great feeling and quick8( onset.

 

[Snake_Eyes]

Well if two doesn't give you a buzz, go to three.. Also chew them instead of swallowing them whole. So chew 3, wait an hour or two ( That's about how long it takes to fully feel the effects, give or take, it's specific to the person, but that's ballpark..), re-dose 10mg every hour or two until you reach desired effects. The daily limit for APAP is 3-4g, so 9-12 of the 5/325's.. Also if you're worried about the APAP, you can do a cold water extraction (CWE). The oxycodone dissolves into the water before the APAP does, so you just strain the APAP out, and drink your oxycodone water. This process is quite simple and quick. There's a shit ton of "how to" CWE threads on this and many other websites... Just type CWE into the search bar.

Directed at the OP...the daily limit of apap does NOT mean it's safe to take all that in one sitting or within the window of getting high. IMO anything over 1625 (5 pills) needs a CWE and even that's pushing it.

 

[Pilll_head]

Other than milk thisle, Tagamet (like 600 mg) is also a good one to take with oxy. It inhibits metabolism so the buzz will last longer and reduces the likelihood of APAP-induced liver damage (also by inhibiting metabolism of APAP). That being said, 3-4 percs is not enough APAP to cause any liver problems. I would stick with once a week to avoid increasing your tolerance. I've been a weekend warrior for 3 years and I've been taking almost the exact same dosage the whole time, my tolerance hasn't budged at all.

 

[pally pete]

Other than milk thisle, Tagamet (like 600 mg) is also a good one to take with oxy. It inhibits metabolism so the buzz will last longer and reduces the likelihood of APAP-induced liver damage (also by inhibiting metabolism of APAP). That being said, 3-4 percs is not enough APAP to cause any liver problems. I would stick with once a week to avoid increasing your tolerance. I've been a weekend warrior for 3 years and I've been taking almost the exact same dosage the whole time, my tolerance hasn't budged at all.

For some reason Tagamet (Cimetidine) does not seem to work when it comes to potentiation of Oxy. Nor does Quinine or any of the other list of potentiation guides.