How to Efficiently Increase Adderall Dose as you Gain Tolerance???

[maddiemax]

I first started taking Adderall back in January (about 4 months ago). It's now May and I think I've taken a total of about 70 10mg pills. Obviously I don't take them daily or consistently, just when I think I need them which is when I have big tests or papers. Right now is finals week so I've been taking the most I've ever taken. However, I think I must have gained a tolerance since I first took them in January.

When I first took them, I would take a quarter or even an 1/8th of a pill, so roughly around 2-2.5mg and I'd be set! Super bad cotton mouth, "zombied" out yet increased focus, NO appetite. I liked the euphoria I felt the days after it wore off so I went through them quickly. Once the semester quieted down though, I back off although I would take them occasionally to kill my appetite because I need to lose weight.

Within a couple weeks, I could take 5mg and still eat meals. So I started taking full pills so that I would lose my appetite but the cognitive effects still remained the same (still very focused and able to stay awake). A month or so later, 10mg wasn't enough to kill my appetite. I could still stay up all night long but I'd craving breakfast.

Now my ideal dose of Adderall is the lowest dose in which my appetite is gone. I mean GONE, as in forgetting to eat or feeling starving yet still not wanting to eat. So at this point, 10mg is really not cutting it. 15mg definitely works, but it's not great (no cotton mouth really). At 25mg my appetite is definitely gone for a couple days. I'm just really not liking that idea. I need a dose 10x higher!!! It has been 4 months, but still!!

I know Adderall really isn't the best way to lose weight because when I come off of it I probably gain back twice the weight I lose cause I want to eat everything in sight. The thing is, it is so effective at reducing my appetite. And diet pills give me really bad insomnia (which oddly I can easily fall asleep only a couple hours after adderall)... But with finals, I am stress eating like crazy not to mention I need the energy to cram for nights. How do you guys deal with increasing tolerance? I don't want to go through pills really fast as they are quite expensive... So what is the most effective way to deal with an increase in tolerance? I've read a little about magnesium supplements? My last final is Tuesday so I'll be taking quite a bit every day until then I just hate the idea of taking 2 pills to get the same effects as a 1/4 pill used to give me...

 

[RichardMooner]

Magnesium is definitely a solid idea, will really help with the development of tolerance.

If I were you, I'd take magnesium on a daily basis, use the lowest dose of Adderall you possibly can, and after finals are over, stop taking them for a good bit of time. There are other NDMA antagonists that can be used to prevent tolerance, but I wouldn't fuck around with them, as taking one drug to mask the side effects of another drug when not necessary, is never really a great idea.

Amphetamines are a bitch, especially when you over do it and increase your tolerance too much, and your prescribed dose stops working. I recently got myself into the same situation during midterms, and it's a real shit hole.

Don't use amphetamines to lose weight. Bad road.

 

[maddiemax]

Yea, I know they're not great for weight loss but honestly, who can resist losing 5lb in 2 days simply by popping a pill?? And I am one of those people who actually does need to lose weight (BMI>38, not one of those skinny women who think they need to be even skinnier.

 

[ThatOneDude!]

yah so i take 500mg of Magnesium Citrate daily, at least! the citrate form is much better due to absorption rate! also i think its glycinate? i forget, but that has even higher absorption rate! definitely a key unless you wanna cold turky amphs and take shit tone of magnesium for long period of time for noticeable effects!

I have been able to reduce my tolerance with magnesium citrate. altho the rate at which amphs increase calcium levels in brain is MUCH faster than the rate at which magnesium levels will go up (hence calcium levels down.)

and yah PCP is a very powerful NMDA antagonist! although i wouldnt even think about it! haha, honestly magnesium supplements are best thing i've found!

ALSO: Take amphetamine potentiators!!! stuff like Omega-3 (fish oils) or the 5 hour energy shots they have Taurine, L-Theanine, L-Tyrosine and L-Phenylalanine and then the Citicoline + Niacin not to mention the caffine! all help potentiate the effects of amphetamines! (last 3 not so much directly but in terms of desired effect) Then there is baking soda! Dont do too much or you mess up your stomachs pH! as acidic drinks will do the opposite and lessen the effects! I am a little uncertain as to what exactly vitamin-c will do, but yah the acidity is to be avoided, Another reason 5 hour energy shots rule over the energy drinks!

 

[maddiemax]

thanks! i have magnesium + calcium vitamins will those work? and i also have some krill oil, will that work like the fish oil?
and i looovee 5 hour energy drinks! i did not know that they can increase effects of addys! so awesome, never buying red bull again haha!

 

[maddiemax]

also, how long do u think id need to go cold turkey before id get back down to only needing a tiny dose? like i said, i started in jan and don't take them every day... i just take maybe 20-30/day for a couple days in a row (actually it may be closer to 50 for finals now) only twice a month or so... basically i've taken about 170-180mg in 4 month which turns out to be a 10mg pill every other day but like i said i go a couple weeks at a time without taking any yet my tolerance has still increased a lot!! ;(

 

[RichardMooner]

thanks! i have magnesium + calcium vitamins will those work? and i also have some krill oil, will that work like the fish oil?
and i looovee 5 hour energy drinks! i did not know that they can increase effects of addys! so awesome, never buying red bull again haha!

Avoid Calcium. Amphetamine tolerance is caused by an influx of calcium ions in the NDMA receptors...I believe. So more calcium=faster developing tolerance

 

[ThatOneDude!]

Avoid Calcium. Amphetamine tolerance is caused by an influx of calcium ions in the NDMA receptors...I believe. So more calcium=faster developing tolerance

Yah that was my understanding as well.

And going cold turky will speed up the process for sure! however just taking the magnesium supplements while continuously doing speed (from my rescent events) has managed to prevent tolerance from building. and however much break i give myself, gives the magnesium chance to work without the amphs and just start to really bring down the tolerance. from personal experience, i've gone 1 week cold turky with about 600mg of mag citrate a day, and end of the week noticed significant decrease! nothing drastic nor a really big difference, but I was DEFINITELY noticeably lighter weight/more sensitive.

i would try 1 week cold turky, see how your body reacts, and how fast your brain can adjust. then go from there. Im sure if you went cold turky a month, with constant magnesium daily, you would be super light weight hopefully, (applying your example) after a month cold turky you could probly get good long and strong effect from a 20, im not sure exactly what levels your at, i could be misinterpreting where your at.

I know i do a lot of meth sometimes! snorting away day after day. the magnesium was not keeping up to reduce tolerance buildup completely, as i did a lot of meth. but after just 1 week cold turky i noticed substantial decrease! do the citrate or glycinate versions with the HIGH absorption rating, that will make ALL the difference IMO.

and yah your looking for Omega-3 when it comes to fish oils, i'd read the label and see what its got!
I was personally surprised when taking a bunch of potentiators together with a good dose, i definitely felt "lighter-weight"

EDIT: Yah i just read where you mention how often you do addys.... honeslty comparing to my constant use of meth. you could probly continue without trying to go cold turky seing as its only a few times a month, just take like 6-800MG of Magnesium Citrate (for example) each day, maybe devide the dose in half and take every 12 hours? idk if that makes better use of the magnesium intake. but yah doing that daily, you should notice those few times a month having more kick! altho im only guessing based on my own experiences

 

[maddiemax]

I actually just learned in my neurobio class the signal pathways ways in neuronal cells and yes, calcium is a big player so I'm not surprised that it causes the release of dopamine through the influx of calcium and having extra calcium in the brain would somehow increase tolerance because the adderall has to work harder to release more calcium (maybe?? id love to learn more about it on a molecular level if anyone has more knowledge??)

however.... i don't think it is possible really for the calcium in vitamins to cross the blood brain barrier and enter into the brain.. same with magnesium. so i researched it and found this article: http://www.sciencedaily.com/releases/2010/02/100222162011.htm

They say: "we've also been able to show that today's over-the-counter magnesium supplements don't really work. They do not get into the brain." so... I'm not quite sure how effective taking vitamins will be and if it will ultimately turn out to be more of a placebo effect... That being said, i just bought a bottle of 100% fast absorbing magnesium citrate (without calcium) to give it a try and i stocked up on 5-hour shots

ill pretty much be taking addys non stop till tuesday and then i probably won't take them for a while... hopefully i will be closer to super lightweight like before, from what i've read 20-25mg still seems like a small dose but is crazy high compared what i needed before at .25-.5mg

 

[mygreenbic]

Dxm in low doses will help keep your tolerance from skyrocketing. Just be careful not to take too much as dxm is an extremely dose dependent dissociative psychedelic. If you aren't well versed on dxm I advise that you read the dxm faq by Dr William White which can be found here:https://www.erowid.org/chemicals/dxm/faq/

I just want to remind you that you are dancing on the edge of a razor blade. Amphetamines are a very powerful and addictive drug. If you are trying to plan out how to successfully get high off of it forever, chances are forever won't be too much longer for you.

That being said, be safe and be careful.
Note: please educate yourself on seratonin syndrome before using dxm to reduce amphetamine tolerance

 

[mygreenbic]

That

 

[maddiemax]

I've learned that dxm and adderall can be deadly together like taking cold medicine & adderall together and u risk heart attack... thanks for the tip tho, i hate psychedelics though... they make me crazyyyy 8(... I've had quite the experiences many times with its cousin ketamine in a hospital...
I'm really not looking to use amphetamines on a daily basis or really on a regular basis... just during finals and maybe a couple other times during the semester... i just didn't expect that i would gain 10X tolerance when i only use it a couple times every 2-3 weeks

and i know amphetamines are very powerful, i study their effects on paper & in rats in grad school... i know there's a reason they are Schedule II with cocaine and methadone/morphine... but honestly now that i have personally taken them since a doctor thought they'd be helpful with focus, energy & depression... i just don't feel these powerful effects... I've taken my fair share of drugs and really the effects are just not as profound as hallucinogens or opiates or even stronger benzos... i don't even feel psychologically addicted to it, if they were taken away from me i would be totally fine practicing proper time management (maybe a little bummed?) but while i have them, my attitude is, "why not take advantage while i have them?"... (i got A+s on my grad school chem & neuroscience classes by cramming the night before with addys, i mean seriously it is amazing!)

although... i feel like in theory it could last forever if i take long enough breaks often enough... i doubt my tolerance would ever get back down super low but i don't think it would get crazy high either... idk... luckily my last finals will be done with in a couple days

 

[mygreenbic]

Ok, first off i apologize for the advice. I think that dxm and adderall might be a horrible idea. I took 200 mg dxm and i snorted 20mg or so adderall about 40 minutes later forgetting that i took the dxm.at first i felt utter euphoria like i never felt before on adderall. Usually i can't feel twenty mg adderall. But now I'm feeling amphetamine comedown while I'm tripping on dxm. Although my advice was to take small non psychedelic doses of dxm for potentiation, i could now see why people would warm to steer clear of this mixture. I'm craving redosing add so bad but I'm do confused because I'm tripping and concerned about my health. I have alcohol and clonazepam. B I'm thinking the clonaz will help but i can't seem to take it. My mind keeps going in circles telling me that i want to redose adderall. The circular thoughts are driving me mad. I wish i had someone to talk to

 

[RichardMooner]

Ok, first off i apologize for the advice. I think that dxm and adderall might be a horrible idea. I took 200 mg dxm and i snorted 20mg or so adderall about 40 minutes later forgetting that i took the dxm.at first i felt utter euphoria like i never felt before on adderall. Usually i can't feel twenty mg adderall. But now I'm feeling amphetamine comedown while I'm tripping on dxm. Although my advice was to take small non psychedelic doses of dxm for potentiation, i could now see why people would warm to steer clear of this mixture. I'm craving redosing add so bad but I'm do confused because I'm tripping and concerned about my health. I have alcohol and clonazepam. B I'm thinking the clonaz will help but i can't seem to take it. My mind keeps going in circles telling me that i want to redose adderall. The circular thoughts are driving me mad. I wish i had someone to talk to

Hey, man. Wish I'd seen this earlier. Everything work out alright? Hope you didn't redose....

 

[mygreenbic]

Hey, man. Wish I'd seen this earlier. Everything work out alright? Hope you didn't redose....

No things are bad. I redosed a tiny bump of add like 5mg because the adderall comedown on dxm was pure torture. Now i think I'm crashing off both and tactile sensations are bad. The dysphoria is extremely intense, and panic attacks because of the fear of possible fatal event from what I've read about the combo. Really scared and in pain

Would some lyrica help?

 

[maddiemax]

no i would not take anything else!!! just adding more drugs on top of everything is seriously gonna make it worse.. at the very least maybe a tiny bit of klono to get heart rate down.. just try to relax.. lie down in a room with dim lights (i know no lights would freak me out in that situation).. really don't take anything else especially don't take more adderall... lyrica is a downer but i think a little klonopin would work better.. do u happen to have any anti psychotics? seroquel is pretty common, that is basically the opposite of adderall.. but actually i would just take nothing else... try to drink water and relax find an actual person to talk to if you can!

and don't do anymore reading about the drugs what is done is done unless u want to make urself throw up but looking at the time stamps i think its too late for that and honestly if you haven't had a heart attack by now, ur not gonna get one unless u redose (u would have gotten a heart attack minutes after snorting the adderall) by now the drugs are being metabolized so i wouldn't worry about sudden death but if you are maybe call an ambulance? but again, don't be scared, ur heart rate peaks minutes after insufflation so as long as u don't take anything else that increases ur heart rate u will be fine just don't work urself up..

hope everything works out! keep us updated!

 

[mycrowis_name]

if you took DXM and Adderall.. you would get sick at the very least feel....disgustingly awful feelings
...more then likely throwing up...i've seen and experienced it myself.
just don't.....maybe after the amphetamines wear off.... i can see that going fine if you're trying to party....but....

as for adderall dosages...depending on your age weight and maybe gender.... according to the FDA 30 MG's should be the max dose for Adderall XR.
but then again you can take higher doses ....if you don't have heart problems....i'd say drink water mainly i've heard it absorbs that way....and as for food when i take Adderall i try to stick with soups.... during my teen years one of my doctors had me on 3X 20mg's XR daily.

 

[RichardMooner]

No things are bad. I redosed a tiny bump of add like 5mg because the adderall comedown on dxm was pure torture. Now i think I'm crashing off both and tactile sensations are bad. The dysphoria is extremely intense, and panic attacks because of the fear of possible fatal event from what I've read about the combo. Really scared and in pain

Would some lyrica help?

Hey, man. You're okay. You're just panicking. The biggest problem with the combination is the elevation in heart rate from both substances, and given your dosages, assuming you don't have a preexisting heart condition, you shouldn't worry about it. Especially considering that they're both wearing off.

If you had serotonin syndrome, you would know by now. Adderall's serotogenic properties are pretty minuscule. (Doesn't mean the combination is safe and SS isn't a risk, or doesn't happen) but it would a rare happening, and panicking over it isn't worth the trouble.

I'm not too familiar with lyrica, so I shan't say if it is or is not okay, but I wouldn't take it. Just because you don't know how you'll react.

Hope all is gong okay man. Just try to lay down, relax, take deep breaths, and try to take your mind off of it. If you have any benzos, it would be safe to take a low dose to calm you down + negate a lot of the negative side effects of the comedown. Not too high though, wouldn't want to blackout. A longer acting benzo is preferable, that way you don't have to redose when it wears off. Shorter acting benzos will work just fine though.

Hang in there man, keep us updated.

EDIT: Try to eat something, drink some sports drinks or fruit juices (if nothing else, some water), and take some Vitamin C. It'll help get the amphet out of your system a bit faster.

 

[Ds]

Well, my doctor used to write me 60, 30mg addys a month, at the time I was seeing another psych doctor and he was writing me the same thing. Needless to say that I did not even make it 7days that week because i took em,sold em,traded them,and even let a chick suck my dick for afew.

I wasnt feining because I had traded most of them for benzos and opiates.

So to answer your question, I don't know. I cant like be perscribed to it over a long time because of what I mentioned above.

 

[maddiemax]

well now i can't tell if I'm coming down off of it or I'm still high.. such a weird feeling, I'm so emotional and so angry at everything.. i still feel my heart pumping, i have no appetite, i can't sleep too much, I'm so nauseous & my head hurts, and i get these moments where i feel so depressed
its like a mixture of coming down yet still stimulated.. which sucks! comedowns i don't think are normally too bad for me because i just sleep it off but i can't this time and i have no benzos or anything (not that i needed those before...) its been 12+ hours since my last IR dose... i actually don't even remember how much I've taken in the past few days.. as soon as id get tired or feel unfocused, id pop half a pill, probably went through 60+ since sunday
i am ready to get back to normal i just wish i could settle down if i could sleep i wouldn't have to deal with this swings between sadness & anger