How scientists have betrayed us in the war on drugs

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https://ricochet.media/en/485/how-scientists-have-betrayed-us-in-the-war-on-drugs


NEWSERIN SEATTERJUNE 17, 2015​
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0 Comments [h=1]How scientists have betrayed us in the war on drugs
[/h]Columbia University professor Carl Hart speaks out about what researchers aren’t telling the public


“If I’m going to a boring party, I should be able to take an amphetamine to stay awake. I know what I’m doing.”


The audience laughs, recognizing first the ordeal of a tedious social function, then the frankness of the statement.
Every few years, the media declare a new drug epidemic, a new worst addiction.
Carl Hart means what he says. The Columbia University professor has spent decades studying how drugs affect behaviour and the brain. He entered the field of neuroscience hoping to solve addiction, believing it was the cause of the problems he saw at home in Miami. An epidemic of crack cocaine hysteria had broken out in the mid-1980s, and the drug took the blame for a variety of ills in black communities — violence, crime, poverty, crumbling families, a generation of “crack babies.”
But after years of investigating the effects of drug use, and reflecting on his own life, the evidence piled up before him: drugs weren’t the issue.

[h=1]Science’s silence[/h]About 300 people in Vancouver have come to hear Hart at a presentation organized by the Canadian Drug Policy Coalition. One of the first things he says is that he has used and sold drugs, and even carried a gun.
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He’s one of few black people in the room, and stands out in a suit, with dreads so long he has them partly tied up. His highly readable and compelling memoir High Price details his remarkable journey from a childhood of entrenched poverty to a career as a world-class neuropsychopharmacologist. He writes that he resolved to lock his hair as “a way to show homage and respect,” and remind himself that he could be “a conscious spirit, no matter what other people might decide a scientist should look like.”
The book also undercuts prevailing ideas about drugs. Looking back on his youth, Hart describes his realization that the many social ills blamed on crack cocaine preceded the drug. His father physically assaulted his mother; his parents split up when he was seven, after which welfare became part of his family life; he grew up in the homes of different relatives; he witnessed gun violence; he and his friends engaged in theft; he watched family and friends struggle, with no opportunities for economic and social advancement. All of this was happening before the appearance of crack, the result of long-standing historical and political structures made worse by law enforcement and the drug war.
High Price is Hart’s attempt to disrupt the scientific community’s silence, one that remains ominously loud.
[h=1]Distorted dangers, prices paid[/h]What’s known in the labs hasn’t been shared with the public, says Hart. Scientists have acquired knowledge about drugs through studies funded by taxpayers, and “it seems as though we should give something back to them. We should tell them something about what we know.”
One of his key statistics is that 80 per cent of people who have used drugs do not have a problem. This number underscores that addiction develops for a minority of drug users and that drugs aren’t as potently addictive as we have been led to believe. “The majority … of the people who use drugs are like me,” says Hart. “They take care of their families. They are responsible members of our society. And in some cases, they even become president of the United States.”
The harmful effects of drugs have been exaggerated, he emphasizes, laying out his case with cocaine as an example. Though crack cocaine is typically perceived as a more dangerous and addictive drug, it is virtually the same as powder cocaine. The slight chemical difference between them means that powder cocaine can’t be smoked. (Its melting point is too high, so it just burns up.) Removing the hydrochloride lowers the melting point, and that’s how crack is made. But whether cocaine is injected or smoked, it produces the same intense effect.
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Chemical structure
Powder cocaine (left) and crack cocaine (right) are almost identical on a molecular level.


The mythology that continues to surround illicit drugs, Hart argues, comes with severe consequences. In the United States, the law creates an artificial distinction between powder and crack cocaine. Despite an amendment in 2010 to reduce the sentencing disparity, jail terms for possession and sales of crack are still significantly longer than for powder cocaine. This is a strike against poor black communities, in which crack is favoured because it’s more affordable.
“Black people in the United States represent 80 per cent of those people arrested under the law, even though they don’t use cocaine at rates higher than white folks,” notes Hart. (In Canada, the law is the same for all forms of cocaine. However, Canadian jails also have distorted incarceration rates. Since 2003, the proportion of white prisoners has decreased, while the proportion of black, Asian, and Aboriginal prisoners has shot up. As well, mandatory minimum sentences, implemented under Prime Minister Stephen Harper, are associated with disproportionate punishment of racialized groups.)
Despite scientific knowledge since at least the early 1990s that powder and crack cocaine are nearly identical, the law “is still inappropriate. It’s still inconsistent with the science,” says Hart.
“Imagine someone saying that smoking marijuana was so much more dangerous than eating marijuana in your brownie. That is the equivalent of what we’re doing.”
[h=1]Drug ed[/h]“The most important lesson that I’ve learned about drugs is this: drug effects are predictable. When you hear people talk about the unpredictability of a drug effect, it is a licence to stop listening.”
This means a basic education in drugs could save lives. Hart gives his Vancouver audience a quick demonstration of what could be taught. “The dose is critically important. And so you want to tell young people, ‘If you are a novice, don’t start using drugs or smoking like a champion. Crawl before you can walk.”
Starting with lower doses helps build tolerance. “We talk about it as if it’s a bad thing,” says Hart, but “tolerance keeps people alive. It actually saves people.”
Make sure you’re in a safe and comfortable space, not “an anxiety-ridden environment.” And know that how a drug is taken affects the speed with which it acts. “If you’re taking marijuana orally, don’t expect the effects to happen within 15 minutes. Don’t put more in your gut, because if you do you’re going to have some horrifying effects.”
In an online post, Hart recalls picking up his teenage son from a party and wondering whether his son has used drugs. He asks what his son remembers from their discussions over the years, and it turns out his son has absorbed a lot about how to navigate drug use. “Like most parents, I have discouraged drug use among my children,” writes Hart, but “I am heartened to know that [my son] is equipped with these important lessons because they will decrease drug-related harms, and ultimately save his life if he does decide to experiment.”
These lessons aren’t part of school curricula or health campaigns. PSAs don’t outline the difference between smoking and eating drugs, or explain that heroin and alcohol don’t mix well.
Instead the public is inundated with scary stories based on little fact. Every few years, the media declare a new drug epidemic, a new worst addiction, says Hart. Time magazine obligingly made this point with its latest cover, which he puts up on a screen. This round, painkillers are America’s poison.
“Science has been complicit in this nonsense,” says Hart.
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Time magazine's most recent issue
Feature article: "Why America Can’t Kick Its Painkiller Problem."


[h=1]Captive inquiry[/h]What we as a public might reasonably expect from both journalists and scientists strikes me as quite similar. As a minimum standard, each group should pursue truth, recognizing and mitigating biases to the fullest extent, working with a dedication to ethics and the public good, with an aim of gathering and sharing knowledge broadly.
But corporate imperatives dictate news coverage, impacting journalism in explicit and indirect ways. Likewise, following the money in science is revealing.
An astounding 90 per cent of the world’s research on drugs is funded by a U.S. government agency, the National Institute on Drug Abuse, says Hart. Its mission is “to lead the Nation in bringing the power of science to bear on drug abuse and addiction.”
“Their focus is almost exclusively on pathology,” says Hart. In other words, they want to know all the bad stuff about drugs. They don’t want to hear anything else. (Despite his views, Hart manages to sit on NIDA’s advisory council. “You can imagine what our meetings are like,” he remarks at one point.)
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Dirty money and cocaine
"Q: What do cocaine and bacteria have in common? A: They both contaminate our cash." An infographic for teens from the National Institute on Drug Abuse. Click to expand.
NIDA

Drug researchers are at the mercy of NIDA for money to fund their studies. It’s easy to imagine how this shapes their grant applications, the research they pursue, and the way they interpret and present their findings.
In a 2011 journal article, one he says he’s proudest of, Hart reviewed the research on meth and cognition. A widely held view is that meth causes damage to the brain, impairing a person’s memory, attention, and learning. But when Hart looked closely at the data, he found that meth users’ cognitive functioning actually fell within a normal range. The researchers had drawn unsupported conclusions, showing “a propensity to interpret any difference, whether it’s a brain difference or whether it’s a cognitive difference, as something that is clinically abnormal.”
Scientists err on the side of caution, because they don’t want to be seen as condoning drug use. “And we do that as scientists as if there is no consequence to this behaviour,” says Hart, but it “has contributed to the environment where certain drugs are deemed evil and any use of these drugs is considered pathological. And then, in the case of the United States, we have this unrealistic focus on eliminating certain drugs at all costs or any costs, particularly for some groups.”
“What does that mean for what’s published in the scientific literature? What does that mean for what’s published in a textbook? In the popular press? In our movies? I don’t know if Breaking Bad has made it to Canada — you have those [kind of] TV shows. All those sorts of things perpetuate misinformation about drugs. But it all kind of starts with this biased focus of our major funder.”
“The spotlight is on pathology, and that’s where most of us are looking,” says Hart. “We’re missing an opportunity to actually contribute to the public education about drugs. We are missing the opportunity to help keep the public safe.”
[h=1]‘From your urine to your deeds’: A new focus[/h]People involved in the treatment and public health approach “are just as incompetent and ignorant about drugs."
Honesty in science could bring to light not only basic facts about illicit substances, but the racist histories attached to their illegality. About a century ago, Canada and the United States took a prohibitionist approach to particular drugs — those linked to racialized groups, including the Chinese (opium), blacks (cocaine), and Mexicans (marijuana). Prejudice and conceit underlie the vilification of illicit drugs. The scientific data doesn’t support the current thrust of drug education, addiction treatment, and law and policy. It doesn’t support our revulsion for others.
The stigmatization of drug use “allows us in society to target people we don’t like without explicitly saying so,” says Hart. “It also allows us as a society to avoid dealing with the real problems that marginalized and poor people face — unemployment, substandard education, poor mental health, poor nutrition.”
Media, politicians, law enforcement, treatment providers, and others are complicit in fuelling this stigma as part of what Hart calls the addiction industry. In fact, he says, people involved in the treatment and public health approach “are just as incompetent and ignorant about drugs as law enforcement personnel.”
The minority of drug users who become addicted don’t need treatment programs focused on pathologizing drug use, says Hart. They need individual assessments to see what’s going on in their lives. They need support to figure themselves out.
Whether someone is a good person is more important than their drug use. “I don’t care if they are using heroin or something else in the privacy of their home,” says Hart, advocating that “we move the focus away from your urine to your deeds.”
He lists ways to force change. Learn the science, but study in humanities, to develop the ability to think critically. Make people “play by the rules of evidence,” and hold researchers accountable. Call out racism even if it makes you uncomfortable — “otherwise what kind of adults are we?” Get out of the closet about your own drug use, and confront society’s limited view of what a drug user looks like.
Work to change the legal status of drugs. “We need to regulate the market just like we do with other potentially dangerous behaviours, like driving.” Because the effects of drugs can be predicted, the risk is in what they’re being cut with.
“This is a not a recipe for popularity,” warns Hart. “It’s lonely being out here saying the things that I say…. I have lost a lot of friends as a result of this. Certainly I’ve lost grant funding.”
“But history will judge you favourably, and that’s more important.”
[h=3]Dr. Hart’s reading recommendations[/h]
  • Michelle Alexander’s The New Jim Crow
  • Anything by James Baldwin
  • Nothing about neuroscience
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Bought and recently finished reading Dr. Hart's hybrid book which combines his autobiography with a fundamentally flawed war on (the people who prefer to consume certain taboo) drugs, and I have nothing but praise and admiration for him and his decision to speak out against this legendary injustice which has caused America to slowly descend into a very chaotic, backstabbing, racist, hypocritical quasi-police state.

I do hope more people with his educational background and credentials have the courage to join him, because we need them if we are to end this once and for all. And there's no doubt they are out there and clearly too scared to speak up and out. Here's hoping they find it in themselves to listen their conscience, regardless of the consequences to their careers.

If by chance such individuals are reading this, then I'll say it again: Please, for the sake of the freedom of countless non-violent, otherwise law-abiding human beings who, for reasons probably influenced by their genetic makeup, prefer to use something other than booze and/or nicotine to "take the edge off," I beg of you to stand up and speak out against the war on drugs.
 
But it all kind of starts with this biased focus of our major funder.

Indeed, but who will step up to fund more rational research? I have yet to hear a convincing answer to that question, and until we have one we won't see anything different.
 
I have a lot of respect for Hart and what he's trying to do, but I think he makes the same mistake a lot of anti-WOD people do and swings too far in the other direction (although not to the same degree as some). A good example would be his statement about powder cocaine and crack cocaine being the same drug - yes this is true, but when we're talking about a euphoric, addictive stimulant then there's a huge difference between snorting it and smoking it. I don't think this justifies sentencing disparity or anything, but trying to downplay the difference and tacitly insinuating that snorting a line of coke is the same as taking a hit from a crackpipe is counterproductive to the cause of introducing reasonable, scientific drug policy.
 
^ I don't see that Hart is "tacitly insinuating that snorting a line of coke is the same thing as taking a hit from a crackpipe", in this very article he compares the intensity of smoking crack to injecting cocaine. I see that comparison as an acknowledgement that snorting a line of cocaine and taking a hit of crack are not the same thing. The fact of the matter is anyone who has access to legal powder cocaine will also have access to injecting equipment. You might not be able to draw a direct comparison between snorting powder cocaine and smoking crack, but since powder cocaine users will also be able to inject the drug, which is arguably more addictive than smoking crack, there is no logical justification for restricting access to crack cocaine whilst allowing access to powder cocaine.
 
You know, it's funny, people have this idealized image of science as this bastion of free inquiry, exploratory pushing of boundaries, and unbiased quest for the naked truth. And in theory, yes, it could be all of these things. There's just two little problems:

A. scientific research isn't free
B. researchers are human, with biases and all

Not to be cynical (I'm a scientist of sort by trade, and a big proponent of scientific literacy), but whenever you read a scientific study, always inquire about who underwrote (i.e. funded) it. He who pays the piper calls the tune. I think you'll find that any institution that underwrites a scientific study, is fishing for a very specific set of results that supports their mission statement's biases. If those results are not forthcoming, the funding dries up pretty quickly, and the research project gets the gong.

I discovered this when I went looking for unbiased research on the neurocognitive effects of marijuana. I simply couldn't find any. About 80-90% of the research I found had an unabashed agenda of discouraging marijuana use, and the remaining 10-20% had an unabashed agenda of promoting it and making it look harmless. I know that the truth lies somewhere in the middle (closer to the latter, albeit). But at least presently, there's no one with deep pockets who sees themselves as benefitting from backing up this point of view with hard data.
 
All the scientific research in the entire fucking world hasn't stopped defenceless baby boy's genitals from being routinely BUTCHERED so they can sell their fucking foreskins for a profit...

I'd say that is an INDICTMENT.

Call me an idiot. Call me a fucktard. Call me what you like.

Has science failed us?...I don't know. You tell me.
 
^ I don't see that Hart is "tacitly insinuating that snorting a line of coke is the same thing as taking a hit from a crackpipe", in this very article he compares the intensity of smoking crack to injecting cocaine. I see that comparison as an acknowledgement that snorting a line of cocaine and taking a hit of crack are not the same thing. The fact of the matter is anyone who has access to legal powder cocaine will also have access to injecting equipment. You might not be able to draw a direct comparison between snorting powder cocaine and smoking crack, but since powder cocaine users will also be able to inject the drug, which is arguably more addictive than smoking crack, there is no logical justification for restricting access to crack cocaine whilst allowing access to powder cocaine.

I never said there was, in fact I said the exact opposite. But you have to take the context of use and the primary userbase into account. The fact is that the vast majority of people using powder cocaine don't inject it, they snort it, and they do so in a social/recreational setting, not a habitual one. Crack, on the other hand, is made for the sole purpose of the more addictive smoking and isn't generally used in a recreational setting - it's primary userbase consists of addicts. By comparison those who do inject powder would I imagine do so in unison with another primary drug of choice (heroin users speedballing), instead of having IV cocaine as their primary ROA and DOC (if nothing else, the vein damage would make such a habit unsustainable).

And injecting equipment - especially a steady supply - isn't so easy to obtain in many parts of the world, for better or worse. I know a lot of US states have laws against needle exchanges and the selling of syringes to addicts. Yes, if someone is absolutely determined to inject cocaine for some reason, then they can probably do it, but differences in accessibility do factor into things on a statistical level. I've known plenty of people who refused to shoot up at first for the simple reason that they didn't feel comfortable going into a needle exchange or pharmacy.

All of these factors matter and they make a difference in terms of how much damage the drug does. I don't think this difference justifies sentencing disparity, but to try and ignore it is just as unscientific and counterproductive.
 
I interpreted your initial statement as implying that Hart was being disingenuous by saying cocaine and crack are the same drug. I don't see how that holds up when in the article he made a direct comparison between injecting powder cocaine and smoking crack, I think that makes it pretty clear that smoking crack and snorting cocaine are quite different. I think most people attach a strong stigma to the non medical injection of any drug, and tend to associate most IV use with addiction, rather than recreational use. By comparing crack cocaine to IV cocaine he gave quite a clear and accurate picture of the relationship between crack and powder cocaine, and the typical user base which crack has.

When you said that he swings too far in the advocacy of legalising drugs, then went on to cite the example of comparing powder cocaine and crack, I interpreted this to mean that you felt drug law reform should make some kind of distinction between these two drugs. I realise that in many places access to syringes is limited, but my point was if we were going to legalise cocaine, it would be very strange if we decided to restrict syringes at the same time. With this in mind, there could be no logical basis to restrict crack more heavily than cocaine, because injecting cocaine is just as bad as smoking crack (if not worse), and in a market where cocaine and syringes were legal and available, anyone who wanted an intense high from cocaine would be free to inject it. At least crack doesn't carry the risks that IV use does.

I know you weren't advocating sentencing disparity, you made that clear in your last post. However, I did interpret your post as tacitly saying that if we were to legalise drugs, cocaine and crack cocaine should belong to different tiers of access or something to that effect, which wouldn't make any sense to me. If I misinterpreted you then I apologise. If that is the case I would be interested for you to elaborate on the comment that "he makes the same mistake a lot of anti-WOD people do and swings too far in the other direction". Do you believe that the prohibition of recreational drugs is a practice which Governments should continue?
 
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Walmart in all 50 states sell 100ct boxes of rigs. U have to know what to ask for. "Box of 29 ga 1cc long" 98% will do it. $12.58 with tax. If they try to be a smart ass tell them you have diabetes. You take Novalin 70/30 insulin. 60 units in the morning 40 units at night. Ramble that off quickly like you know what you are talking about and you will get them.
Don't quote me on this but I remember something called "the clean needle act" bill Clinton enacted. It makes it so that selling you syringes is up to the pharmacist. I have had trouble with CVS and walgreens. If you go through the drive through at a drug store you are much more likely to get what you want. When they ask you for your diabetic card just laugh and tell them you are not a card carrying member. I have known multiple diabetics and they have told me there is no such thing as a diabetic card.
 
Do you believe that the prohibition of recreational drugs is a practice which Governments should continue?

Come on, I thought you knew me better than that :/

I believe that the regulation of drugs should take place on a case by case (that is, depending on both the chemical itself and the form which the chemical takes) basis, relying on strict scientific evidence and with a goal of balancing the reduction of harm to the user and society caused by the use of the drug and the reduction in harm to the user and society caused by attempts to impede access to the drug. This regulatory sweet spot is obviously going to vary from drug to drug - a regulatory setup which achieves this goal of minimal harm for marijuana will not be the same as that which will achieve it for cocaine, which will not be the same as that which will achieve it for opioids, and so forth, and reaching this sweet spot will require a slow and steady shift in laws surrounding each drug (or category of drugs) as scientific evidence emerges regarding the effects of these changing regulations. I think this is the only setup which will work, and that carte blanche style legalization would most likely be no better than the current War on Drugs model (possibly worse - although I could of course be wrong, if that's where we end up in the scientific search for the least harm, then so be it).

As for the specifics of which regulatory setup would be best for cocaine, I don't have the answer because obviously the prerequisite research has not taken place, and I'm not going to debate based on some hypothetical future (certainly not one which starts with the assumption that anyone can wander down to the corner store for an 8 ball and a pack of syringes). Any change has to start with an evaluation of the current situation, and the reality is that in our current situation, powder and crack cocaine are, statistically speaking, very different in terms of the effect their presence has on both the user and society. I don't believe this justifies sentencing disparity, but that's because there's no evidence that sentencing disparity (or indeed, jailing drug dealers at all - at least in our current situation) leads to a reduction in harm, and plenty of evidence of the harm that it does lead to.

To get back to the main point, I'm very hopeful that we'll see a shift towards evidence based, harm-reduction oriented drug policy in the future, but I think pushing for a free-for-all legalization based on idealistic grounds (and it is based on idealistic grounds, because we have no idea what such a society would actually be like - scientific evidence against the war on drugs is not scientific evidence for it's complete opposite) is counterproductive to this goal, as is making dubious correlations and presenting them as evidence against the war on drugs (another common one, and one which I believe Hart has also made in the past*, is the comparison of prescription pill amphetamines to street crystalline methamphetamine). These correlations can be useful for pointing out the flaws in the logic behind the WOD, but they aren't evidence of anything except the need for society to constantly question it's preconceptions. Finally, there are frequent attempts to downplay the harm caused by drugs (weed doesn't trigger mental health problems! meth isn't neurotoxic!), which is no better than the constant attempts to play them up by the proponents of the WOD.

*If I'm incorrect on this point, then I apologize - I'm thinking of an interview Hart gave a year or two ago, but I can't remember the exact date or website.
 
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Meanwhile, other scientists--Chinese ones--on the other side of the world have sided with us Western recreational drug users and have decided to flood the gray market with new RCs, and there is *no* end in sight! In the long run, this might turn out to be a positive development--as a few or more new, safe, and good recreational drugs may be found--but for now, RC users are the guinea pigs. And don't think RCs don't sometimes find themselves on the streets later, because they do. As far as recreational drugs being or becoming legal, I think the only realm where good drugs are allowed is in Heaven, or maybe Hell--I can't decide which.
 
I'm amazed we haven't had some kind of MPTP-esque epidemic already, given how many random RC's are being spewed out every week. It's a miracle that none of them have turned out to have horrendous side effects (well, that we know of anyway, maybe 10 years from now all the kids who smashed mephedrone for a few years will have cancer). I figure at this rate, it's only a matter of time.
 
I did meet a girl who said she had some kind of permanent ill effects--I don't remember what--after smoking some kind of synthetic cannabinoid. I wonder if these Chinese chemists even test these new RC creations at all before selling them over the internet and shipping them all over the world? I somehow kind of doubt it!
 
I imagine they do some basic testing to establish potency/effect, but I doubt it's much beyond offering a roomful of poor, desperate people some money in return for being dosed with fuck knows what.
 
I'm amazed we haven't had some kind of MPTP-esque epidemic already, given how many random RC's are being spewed out every week. It's a miracle that none of them have turned out to have horrendous side effects (well, that we know of anyway, maybe 10 years from now all the kids who smashed mephedrone for a few years will have cancer). I figure at this rate, it's only a matter of time.
It really is a testament to the theory of rational drug discussion.
 
The New Jim Crow when it came out, Chasing the Scream when it came out, Hungry Ghosts sometime after the former, and most recently High Price (might have the last two in reverse, but who fucking cares). Worth it to get the first two when they initially came out, the second two I would have if I used to not dislike Mate (not for any reason really... literally no reason, same as the reason most Americans (if not many other peoples)) and High Price was available at the library right after it came out. So many other good books out there.

To add another must read, especially for those interested in drug policy/medicine, Creating the American Junkie(Addiction Research in the Classic Era of Narcotics Control) by Caroline Jean Acker. The Birth of Heroin and the Demonization of the Dope Fiend also prevents a good overview of things, but doesn't really go into anything too deeply, more just parsing things out.

On another note: seadal, I like the way you write :)
 
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