How much is too much 25i-NBOMe?

[OctalBacchus115]

I've done about all the research you can do on this new research chemical known as 25i-nbome. There have been several reports of people dying on this substance, but it's a rare occurrence and I'm confident that it wont happen to me considering I've tried it already and been fine and my history of with psychedelics

Now the one thing I have not been able to find any information on is what happens when you do a lot? I'm not talking about a high dose, like doing the substance 20+ times, once or twice every other week

When I first started taking 25i I thought it was amazing and there were no negative effects whatsoever. Since then I've had a lot easier access to it considering how cheap it is and lately I've been having bad effects. The last time I did it, I dropped 2 tabs within an hour or so of each other and I felt joint pain, paranoia, crazy audio hallucinations that scared the shit out of me and some visual hallucinations that weren't very pleasant either. A reoccurring visual tends to be bugs, like that time while i was smoking i could see these bugs all around me shooting lasers at me and it physically hurt.

Now, this could be for a variety of reasons. At the time I was not in the most stable state of mind, My ex girlfriend committed suicide a few months ago and on top of that I've been more scared to take it since all my friends have been telling me how bad it is for me even though I know they know just as much or less about it then I do.

I haven't had any long-term negative effects whatsoever, just during and sometimes a few days after the trip.

Has anyone else tried this drug a lot that can add their experience with it so I know if I'm going to be okay? I haven't been able to find anything on people who have done it as many times as I have, it's way too new of a substance to know that much about it.

 

[plusfourpirate]

just give your receptors a rest bro, and im sure youll be fine. once or twice every couple weeks is too much for the nbomes. i have good friends who limited their experiences with it to twice a month or so and all have had problems tripping on other substances due to its affinity w certain receptors, nasty side effects, mood swings,etc,etc.

sounds like youve recently been going through some tough life circumstances.. a good time to take a rest and nourish yourself/let your brain return to normal, and maybe try taking something other than nbome in a few weeks to a month. we simply dont know enough about em, except that theyare easy to OD on, vary wildly in proper dose from person to person, and have affinity to serotonin receptors that blow most other psychs out the water.

i feel like such an old geezer when i write these replies, but its like everyday theres at least one new negative thread on this stuff. seems like one of those chems that could be a real gem if used carefully and properly once in a blue moon, but horrible and dangerous for regular use.

hope you feel better man. be safe

 

[any major dude]

Yeah, 25i isn't something you wanna take regularly. Using any psychedelic more than once every couple weeks is asking for trouble, & even twice a month can be problematic for some people regardless of substance. While they aren't addictive, psychedelics to offer a certain escapism that can be desirable to some people who are experiencing difficult life circumstances. Definitely make it a point not to fall into that trap.

 

[.:Holy::Toast:.]

I don't think these are very fun chemicals, te first few times is awesome but it's way to easy to get way to high, and they're so cheap that its way to easy to have alot of doses at hand so you might do it to much.
For a couple weeks I was using the 25i and 25c a few times a week, and it was just a bad idea in general, felt very strung out the whole time, and I'm not positive if this is a side effect of it, but not long after my last dose I developed very painful chronic headaches which still haven't left.
It's been a year and a half and I still have headaches every day

 

[RobotRipping]

25i always gave me terrible muscle tension which lead to headaches. As well as muscle spasms. Otherwise it was a nice drug. I have plenty of experience with it but psychedelics in general, you need to make sure you're ready for the experience. You shouldn't be seeing spiders everywhere or become paranoid. If you are, then you should just stop as you may be heading for psychosis, which is not all that uncommon from psychedelic use.

give it a few months, stabilize your life then try again. I doubt you've done any damage, this is just something that happens to some people with too much psychedelic use, especially if life hasn't been going too well, sorry to hear about your ex. That kind of thing will mess with you psychologically when using psychs twice a month for sure.

no one knows the long term effects, if there are any. No one has figured out why some people take it and die and others do not. If you want to trip twice a month, once you're stable emotionally, go with a 2c-x, at least they have a sound track record and the trips aren't that different, more body load but for the most part, are similar.

 

[Black Rabbit of Inle]

I've found that 25i always leaves me wanting more. After 3 weeks dosing every other day I haven't got to the point of seeing bugs or paranoia, but I do have some severe muscle cramps and have been very unstable mentally. Dosing so often on psyches is a bad idea in general though, regardless of the substance.

Don't do what I do.

 

[RobotRipping]

well damn no wonder, your tolerance must be massive. Once your 5ht2a tolerance hits its max, you're essentially taking a stimulant which does not provide great effects, usually more agitation and irritation than anything else. I've been caught up in the whole 3-4 day tripping per week thing for months and months, usually it ended with a psychotic break. Definitely not a great idea to push it too hard with psychedelic use.

 

[kidklmx]

Noticed any withdrawal symptoms, Re-destributed? I (and some others) think I had them from these (itches mainly), but it could be psychosomatic. If more people have it though, then it's safe to say NBOMes are addicting

With the above in mind, OP, it might be a good idea to keep your blotters away for a little while. Disregarding your personal situation for a moment (which plays it's part too), twice a week is a lot and it could lead to problems down the line. If you're worried about your receptor situation then give it a month or 2. Might be a good idea to find a different psych to do regularly as well since we know so little

 

[weadazoid]

what the hell, this substance should not be abused on a weekly basis. I think the max anyone should see is maybe 4 to 6 of these experiences a year. If you are healthy and find your sweet spot, 2 months is plenty of time to recover and not have a tolerance. Nor would I think one would run into negative side effects if they already responded well to it.

Wanting more? yeah I get that, I suppose, I have very fond memories of my recent 25I indugences, but I am also rational.... this is a POWERFUL something, not to be taken IMO even on a monthly basis. 12 times a year would seem to me to be alot

 

[Black Rabbit of Inle]

what the hell, this substance should not be abused on a weekly basis. I think the max anyone should see is maybe 4 to 6 of these experiences a year. If you are healthy and find your sweet spot, 2 months is plenty of time to recover and not have a tolerance. Nor would I think one would run into negative side effects if they already responded well to it.

Wanting more? yeah I get that, I suppose, I have very fond memories of my recent 25I indugences, but I am also rational.... this is a POWERFUL something, not to be taken IMO even on a monthly basis. 12 times a year would seem to me to be alot

That's you. Not everyone is the same. Your first post just reminds me of all the older hippies that tried to warn me that taking LSD more than 4 times in a year would send me to the nut house.

Noticed any withdrawal symptoms, Re-destributed? I (and some others) think I had them from these (itches mainly), but it could be psychosomatic. If more people have it though, then it's safe to say NBOMes are addicting

I haven't been sober from them long enough to start withdrawing yet (my last message was posted under their influence).

 

[bloodshed344]

That's you. Not everyone is the same. Your first post just reminds me of all the older hippies that tried to warn me that taking LSD more than 4 times in a year would send me to the nut house.



I haven't been sober from them long enough to start withdrawing yet (my last message was posted under their influence).

No, it's not about bodies or opinions. 25I shouldn't be used that often and you're just wrong. Also you won't have any withdrawals, don't be ridiculous. People saying they had withdrawals are hypochondriacs.

 

[Black Rabbit of Inle]

No, it's not about bodies or opinions. 25I shouldn't be used that often and you're just wrong. Also you won't have any withdrawals, don't be ridiculous. People saying they had withdrawals are hypochondriacs.

Actually it is about peoples differing reactions to these drugs. Provide some factual evidence or quit with the baseless claims. I'm just wrong? How?

 

[bloodshed344]

Actually it is about peoples differing reactions to these drugs. Provide some factual evidence or quit with the baseless claims. I'm just wrong? How?

Provide some evidence.


People haven't had any withdrawals. Next you're gonna be telling me about amphetamine withdrawals or cocaine withdrawals. You honestly have no idea how 5-HT2A agonism works do you?

Honestly, no it's not about differing reactions, not in the sense you're talking about.


I just hate how you phrased your post, like it was actually intelligent. Don't be silly.

 

[Black Rabbit of Inle]

Provide some evidence.


People haven't had any withdrawals. Next you're gonna be telling me about amphetamine withdrawals or cocaine withdrawals. You honestly have no idea how 5-HT2A agonism works do you?

Honestly, no it's not about differing reactions, not in the sense you're talking about.


I just hate how you phrased your post, like it was actually intelligent. Don't be silly.

I was never trying to argue that people have or haven't had withdrawals. I was asked if I experienced them and I said I hadn't been sober long enough for them to present themselves, if they were.

You say people haven't had any withdrawals, but how many people have taken these for long periods and given their experiences? There has been no in depth research into the long term effects and at the moment all we have to go on is the collective experiences of those who take them.

You're trying to flat out deny something before there's enough evidence either way.

 

[Deinonychus]

That's you. Not everyone is the same. Your first post just reminds me of all the older hippies that tried to warn me that taking LSD more than 4 times in a year would send me to the nut house.

^This. I'm not advocating *at all* that people do this, but there have been several periods where I've used psychedelics every other day for >1 month. The first time I did this it was with shrooms, my best buddy at the time knew somebody with a few pounds, and we just went all out. It was absolutely great.. until we made the mistake of taking them two days in a row after almost a month of every other day use. That second trip in two days is the only time I've ever felt like I might have seen some glimmers of what true psychosis or schizophrenia is like, I felt like my mind and personality was being split into pieces.

My point is that while we were reckless, nothing had came of every other day use itself, and those results replicated themselves with acid, and PEAs at other, later times in my life.

So this would tend to indicate to me that some people can handle every other day tripping just fine. And it would seem also to indicate that the NBOMe series may cause more physical harm than traditional psychedelics.

Again, don't trip every other day. Unless you're 100% positive that you can handle it – and you might be wrong about that – don't do it. There's nothing impressive or cool about taking scads or drugs. I did it because I enjoyed it, and I'm posting only to point out that some people feel that taking a whole month, or even a whole week, to 'repair' from tripping is not necessary.

 

[kidklmx]

bloodshed344, do you know of any other full-agonists at 5HT receptors that have been used excessively? The only other ones I know of are DOI and Bromo-Dragonfly, not exactly chemicals that lend themselves to excessive use. Look at the cannabinoids for example, no one thought they would give physical withdrawal.

Also, there have been multiple people noticing those itches. And do you see threads like this one popping up about LSD for example? That one is really good at lower "just a feeling" doses and still, people don't overuse it like that. Sure there is excessive usage, but not in the same vein as these chemicals (more to do with escapism than anything else I suppose)

 

[bloodshed344]

bloodshed344, do you know of any other full-agonists at 5HT receptors that have been used excessively? The only other ones I know of are DOI and Bromo-Dragonfly, not exactly chemicals that lend themselves to excessive use. Look at the cannabinoids for example, no one thought they would give physical withdrawal.

Also, there have been multiple people noticing those itches. And do you see threads like this one popping up about LSD for example? That one is really good at lower "just a feeling" doses and still, people don't overuse it like that. Sure there is excessive usage, but not in the same vein as these chemicals (more to do with escapism than anything else I suppose)

Actually even THC can cause withdrawals if you believe the cannabis hyperemesis syndrome or whatever. I just don't think a 5-HT2 agonist, no matter if it's full or not, will cause withdrawals. Not in the classic sense at least.

 

[ToTheMoon]

In my experiences, any amount of 25i is too much, these NBOMe's are just really not beneficial chemicals in my opinion. Was 25i fun at very first taste? Yeah, but there was way too many negative connotations associated with future doses for me to deem it something I'd ever want to consume again. Not much was learned at all, the thought loops are psychotic like nothing I've seen from other hallucinogens.

 

[hazmatz]

I know this is a bit different, but when I've gone through some personal problems while taking psychedelics, I notice that its much more difficult to think clearly the few weeks afterwards...so if you were to ask me, I'd say slow down on the RC use and give your brain some time to make sense of everything.

 

[RobotRipping]

i doubt there would be withdrawals with 25i or any 5-ht2a agonist as well, but if there are, there are. Stimulants do have some sort of withdrawal, the brain is physically changed, and you get fatigued, eat lots and sleep lots. Not much of a physical withdrawal no but i'm sure the same thing could happen from using a PEA psych.

i've abused the shit out of 2c-e and 2c-i and didn't have any issues. I don't see how anyone could trip everyday for a month though, yeah you'll feel something perhaps but after 2-3 days tolerance becomes monstrous and you cannot trip in the real sense of the word, you'll basically have peripheral effects, like taking shitty speed or something. If that's your thing you may as well just go abuse stimulants. Who the fuck knows what may happen if you take 25i in that kind of frequency, could cure cancer, could destroy your brain, cause withdrawals, make you into God... we just don't know at this point. And 25i is not something i would want to be the guinea pig for.