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Opioids how much fentanyl is destroyed when ppl smoke it?

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dr_ange

Greenlighter
Joined
Feb 12, 2014
Messages
5
loooong time reader, first time poster.

i have had this discussion with a few different friends lately, thought id post the question here. i dont think there is any real actual way to tell.. maybe there is, but:

assuming some of the active ingredient is destroyed by heat, when a user smokes fentanyl, how much fentanyl do you think actually makes it into their body?

lets say if a user was to smoke 50 micrograms of the stuff in a light bulb vape or off tin foil, how many micrograms would actually make it into their blood stream?

-dr.ange-
 
Way too many variables to say with any certainty.
What form is the fent in?
how hot does your lighter flame get?
How thick is the glass of your 'bulb'?
And how good is your vape technique?....
At a rough guess, id say you'd lost at least half of the drug through vaping but ive never came across any hard data regarding vaping fent as its a purely recreational activity and relatively new trend.
 
thanks for the replies.

was more just talking 'in general' and was going to relate it to 'practically any opiate'... not really worried/thinking about the exact specifics behind your exact vaping process.

this conversation started when a friend said something about 'your getting 100% of it into your blood stream when you smoke it' and me saying 'not a f'in chance man, heat destroys a lot of it'

so, typically speaking, you guys think its fair to say that you loose about half of your fent by vaping it?

do you think its also fair to say that if a user switched from vaping fentanyl patches to using them transdermally that they would need about half the amount? (to get about the same amount in their blood stream)

thanks again.
 
Transdermal application has the highest bio-availibility, somewhere in the 90% range.
So, yeah you would get get almost all the drug into your system through this ROA but it would be at a slower rate then smoking.

In the interest of HR though, I would advise against using fentanyl recreationally.
The line between high and dead is so fine, its scary.
 
Last edited:
Yeah, transdermal obviously the best for bio availability. thought it was quite a bit higher than 90% still.... no matter.

N, yeah, slower rate, i get it. ive seen fent around many ppl for a good couple years now. almost all brands, all sizes and forms.

n also, yeah, dont be stupid, but that line between high/death isnt -that- close, well, at least its not scary to me, but i respect myself and the drug. i do preach to others about using it 'safely'.

was waiting to be advised not to use it. :)
 
I threw the warning out because I wasnt sure how experienced with fentanyl you were.
I hope I didnt come across as preachy.lol
Ive seen so many people OD on fent that im pretty convinced that 99% of people cant use it with any degree of safety (you could be in the 1%, I dont know.lol).
BA is a little higher then 90% but it depends on other variables, what the actual percentage is (like skin temp or acidity etc etc).
 
Is there like a truck I miss evryday that has ms contin, fentanyl, morphine, dilaudid etc on it? Like an ice cream truck but different? cause I cant get shit but my 200mg of doane everyday....
 
bunge,

All good. Very very experienced though.. id even say too experienced, if you know what i mean.

Finally my friend understands that heat destroys opiates.

Thanks for information/opinions.

Ona bit of a side note, do you or anyone have any information/opinions as to wether its worthwhile to 'recycle' a smoked fent hit? Meaning breath it into a balloon or something and then back into your lungs a second, even third time?
 
^
Well its a difficult one to answer as theres no realhard data on fent smoking.... At an educated guess id say 'recycling' a hit in the way you described would be very low in effect.
Fentanyls melting point is quite low (around 87°c) so I think any remaining fent would condense in the balloon fairly quickly.
An interesting (and prob a bit healthier) way of taking fent would be to dissolve it in saline and apply it by the intranasel route in a spray form.

Make sure your maths on doses is right though because it has a BA almost as high as transdermal ROA.
 
I kinda figured the same about it condensing quickly.... i think sometime soon im going to let a sober friend inhale all my exhales. kinda gross, but its all in the name of science.

Funny you mention the nasal spray. ive been thinking about it a lot lately.. came across the idea about it in another thread recently, seems super covert to do. seen extracted fent multiple times with both iso alch and methanol, typically from the 'new' matrix patches. just really dont know which nasal spray it should actually go in, no empty bottles of any brand around, but there is saline. some would have to be brought regardless, just for the applicator bottle. prolly going to sort something around this within the next week.

n yeah, aware of the ba and the maths behind this all... simple to calculate it all tho. :)
 
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