Not again.. This is the most basic of questions, and one of the most popular questions on bluelight. The simple answer is this: The typical wait time is 12-24 hours, depending on the person. The best way to gauge when you're ready, is to wait unitl you are in moderate to severe withdrawals. Simple as that. Hold out as long as you can after your last dose of whichever opiate/opioid you are using.
That said, PLEASE USE THE SEARCH ENGINE. The suboxone mega thread here in other drugs has everything you need (plus more) to know about suboxone.
I'm closing this since this is beyond redundant. You've been here long enough to know how we operate; the search engine should be your first course of action.
Closed.