So I don't know how to quote from one thread into another (I tried, maybe someone's got a pointer)
So I'll copy and paste from the big and dandy MXIpr and leave it at end of this post.
As far as there being an overlap between the tryptamine and disso breakthroughs, they are completely different experiences. So it's difficult to really compare and contrast them for me because as
@Cheshire_Kat said, "you'll never know where you go" especially with the dissos. In general, the DMT and 5-meo-dmt spaces I go to are quite similar but I cant say the same for dissos which is one reason I find them fascinating.
I've had a few breakthroughs on DMT, 5 meo dmt, and have had disso breakthroughs/holes on 300mg R ketamine (which actually did remind me of ayahuasca come to think of it. It was extremely immersive and visual, but wasn't as cosmic as my 5 meo or MXIpr, I've had 2 deep MXE holes and they were nothing alike lol (in one experience, time was glitching as I was playing video games, and the other i was in bed having visuals that were so similar to alot of the AI generated video that's coming out these days that were so strong I could not trust my sight or my steps or even knew where the walls in my bedroom were everything was shifting rapidly) and then the MXIPr 2F-DCK DMT combo
As far as the comboing of psychedelics with dissos, it's not something I do frequently, but when I do, its fucking insane. Ive only done it twice actually and both experiences were complete OBE and ego loss where I forgot was me or even had a physical body. Be careful if you attempt please.
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"So I dont use dissos frequently, but a few days ago I had one the most psychedelic experience of my life.
I'd been doing small lines of 2FDCK over a few hrs, prolly 150mg or so and I walked my friend home. When I got back I felt like I could handle a little bit more, so I pulled out a 50mg sample of MXipr and insufflated it. I may have taken a toke of dmt, when I came to it had been moved.
Anyway I had a complete OBE spiritual experience. I'm honestly still a bit in shock and just exhausted but it's been about 36 hrs. Umm in a nutshell, I basically became aware that I was a single point of conciousness In the center of a massive toroid structure. Withikely trillions of colored lines that were constantly moving. I spent easily 10,000 years in a state of complete nirvana before remembering my original existence and as soon as I had a memory of it, I started to slide down one of the millions of colored lines of the toroid. As I moved I watched all the other lines moving in a different way and they started turning into these waveforms and then into water. Which I realized was the ocean. I could hear it as well. Then I remembered someone I love, and then I remembered who I was, and that I can control my body with my mind so I opened my eyes to find myself in my little house 1000s of miles away. I've never had such an experience and I've had several breakthrough experiences with 5 meo dmt."