• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

how do u remove benzthonium chloride from ketamine mixtures?

I

intensemoments

Greenlighter
Joined
Sep 11, 2008
Messages
11
A kitten I know was able to acquire a limited supply of ketamine that is pure white and has large crystals, and was extremely more psychedelic, less likely to cause unconciousness, and was extremely more expensive . This kitty inhaleed quite a bit and reported none of the saltiness that he found with all other batches of K. he said it was free-base, free from benzthonium chlorides and chlorbutanals. How would someone else be able to clean K?
 
He may have just been lying about that, because I'm not sure how you'd go about that.

Was this racemic ket or S-Ketamine? Is the commercial Esket formulation (or whatever it's actually called) free of these things? I know that chlorobutanol has been indicated as a possible cause of brain lesions and all sorts of problems that aren't actually caused by ketamine.

I don't think it was freebase either if it was fluffy crystals. What did it actually taste like? It should have been really bitter if it was a freebase.

wow, I haven't answered aything.
 
A/b the ketamine to get rid of the chlorbutanol, then wash with cold acetone to get rid of the benzthonium chloride. That should work okay. The freebase should be obvious to get from there.
 
What is the puprose of using a freebase though?

Also, what form is the freebase, an oil, a crystally solid or more like the sort of waxy gunk that is freebase cocaine?
 
You could of course, just sublime the chlorobutanol off from the ket salt, its volatile.

Save it of course, its a sedative as well as a preservative.
 
Washed K

My friend said that It was a mixture of two different bottles mixed together then dried, the stuff was pure white, had large faceted crystals tasted bitter, and when hit the nostrils felt very clean...all the other stuff he had tried before was white and crystally but just a little to alot off yellowish, and had a dirty saltiness in a lite to heaviness depending on batch, and a slight doppiness to it. This stuff was purely psychedelic, Ive read dreams and realities by Jansen, Ive heard about clandestine labs making pure K. This stuff was unbelievable...so visual and thought invoking, the holes...in the float tank. My friend swears by The Mda/lsd/k/dmt/sex/music/bed/ lotsa herb....

So acid base extract the crystalized K, wash with cold acetone, wash with cold acetone while it is in acid or base form? whats the best acid and PH to use? How high to basify? Best extraction solevent?

Too scared to do K unless its as clean as the stuff he used to get...Hate the benzthonium chloride taste, love the K high...hate wasting it in my nose, dont want to go their with the needles...He needs a beautiful Night Nurse!
 
EsKET

Havent heard of this brand...I will ask my friend about it if it is the same one...Man this stuff was amazing, and pricey...fully psychedelic, He has tried K's and this stuff is the best...Must be the S+ or whatever the most psychedelic is...I must find out more...
 
So how do u go about...

Taking Normal K and cleaning all the unwanted shit out, then changing it all the S+ molecules...or the most potent Psychedelic molecules?
 
I would basify with NaOH to a ph of 9 or 10, or until a precipitate forms, then add hexane (or nonpolar solvent of your choice), wait for the precipitate to migrate a bit, dispose of the aqueous layer. Wash the hexane layer a few times with H2O then add H2O and acidify with HCl acid (it doesn't take much, less than a mL if you did the washes correctly). Agitate and give it a few minutes. Remove the hexane and then dry the H2O layer (or vacuum distill if you have the option), yielding white crystals of ketamine HCl. Put the ketamine in filter paper and rinse with cold acetone. Soak/rinse the filter paper in warm H2O until the ketamine is dissolved. Dry out the H2O on a plate and you should have pure ketamine, in theory anyway. This is probably only useful if you have 10+ grams of ketamine.

Separating the enantiomers requires tartaric acid and more equipment and a longer procedure -- the patent is out there on how to do it if you really want to.
 
Last edited:
Taking Normal K and cleaning all the unwanted shit out, then changing it all the S+ molecules...or the most potent Psychedelic molecules?
Click to expand...
Good luck with that. Maybe if you pray to the magic chirality fairy, she'll come and make all of it single enantiomer (S)-ketamine. ;)
 
Benzalkonium chloride is deemed safe to be injected, so why all this concern about snorting it. About it tasting bad, it's only present in less than 1 percent and anyway ketamine is a pretty vile tasting brew on it's own, I can't see how 0.25 percent is going to have that much effect on taste unless it's up there with quinine for taste bud sensitivity
 
Changing it too S- molecules

nuke said:
I would basify with NaOH to a ph of 9 or 10, or until a precipitate forms, then add hexane (or nonpolar solvent of your choice), wait for the precipitate to migrate a bit, dispose of the aqueous layer. Wash the hexane layer a few times with H2O then add H2O and acidify with HCl acid (it doesn't take much, less than a mL if you did the washes correctly). Agitate and give it a few minutes. Remove the hexane and then dry the H2O layer (or vacuum distill if you have the option), yielding white crystals of ketamine HCl. Put the ketamine in filter paper and rinse with cold acetone. Soak/rinse the filter paper in warm H2O until the ketamine is dissolved. Dry out the H2O on a plate and you should have pure ketamine, in theory anyway. This is probably only useful if you have 10+ grams of ketamine.

Separating the enantiomers requires tartaric acid and more equipment and a longer procedure -- the patent is out there on how to do it if you really want to.
Click to expand...


Do u have a link to this patent?
 
Benzthonium or Benzalkonium?

fastandbulbous said:
Benzalkonium chloride is deemed safe to be injected, so why all this concern about snorting it. About it tasting bad, it's only present in less than 1 percent and anyway ketamine is a pretty vile tasting brew on it's own, I can't see how 0.25 percent is going to have that much effect on taste unless it's up there with quinine for taste bud sensitivity
Click to expand...



Yes safe to inject, but it does change the snorting flavor, as well as
(dont quote me) it has a unwasnted tranquilizing effect? The pure K that my friend is talking about has a deffinete bitter taste but it was a better bitter than the unclean K.
Learning the recipe to convert it all to the most potent psychedelic is important!
 
^ It doesn't cross the blood brain barrier (it's a quaternary amine) so any sedative effects are the result of an overactive imagination. Can't comment on the taste though as I don't snort anything (delicate little sinuses =D)
 
Dreams and realities

Jansen says in dreams and realities that Benzthonium chloride affects the brain in a sedative way...he doesnt elaborate on it though, he also mentions K that is free from it and chlorbutanol and he refers to it as "freebase"....would that be free acid? He says that this free K has a different effect on the user. My friend says that the K he had has to be that stuff, he cannot do any that hasnt been cleaned since, says its like going from dental grade to whippits! The only people who dont prefer it are those who havent had it, as far as it being all the S+ molecules? He said it was way more visual!
My friend says that all other K he has tried has more of a doppiness to it, a more sedative effect, he says this cleaned up super K was deffinetly sedative in itself but a different sedative, or less of a sedative and less dirtiness, he says all the other stuff tastes and feels dirty too him now...he knows a bit about what he is talking about...I think it goes beyond imagination.
 
How to take the regular shit and turn it into the super shit?

So we have how to clean it.....anyone have the way to convert it?
 
Chlorbutanol is a sedative (local pet shops used to sell gelatin capsules to prevent carsickness in dogs - don't have a dog, but I bought a hell of a lot!), but nothing in the BNF says anything about benzalkonium chloride having sedative effects (which would be expected for a quaternary amine).

As for converting it, optical isomers aren't interconvertable without serious synthetic chemistry (and as we know, synthesis discussion is verboten). That said, S(+) ketamine is less dopey and has less hangover effects as it's cleared from the body faster - leaving the assumption that it's the R(-) isomer that gives the dirty, fucked up effects
 
Do pet shops still sell such? or was that phased out long ago?

If not, its acetone and hypochlorite by the bucketfull....

(people thats NOT a way to synthesize chlorbutol btw)
 
thank u

Thanks to everyone for helping with this forum...I still feel that benzthonium chloride affects the trip...and I think after 15 years of snorting im over it and going to the Im, thanks again, cant wait to forum with everyone some more!
 
I've always wondered why 100mg ketamine/mL in one 10 mL bottle boils down to 1.2g powder after drying under convection. I've always figured that extra 0.2g was benzethonium chloride--an invert (N+) soap--but who knows?

I do know that I have had recrystallized k that was much stronger and more hallucinogenic than the whiter, more powdery stuff. I don't know what procedure (solvent or solvent pair) they used to get it though. It looked like (methamphetaminic) ice/shards.

Also, certain brands (eg Ketaset) seemed intrinsically stronger than others (eg Ketalar). It's too bad the stuff's so darn neurotoxic, though. It made me have dark, violent thoughts.

People will yell to the hilt about the dangers of 1970's era prescription PCA (para-chloroamphetamine) but ketamine's Ar-Cl is deemed safe. And it is, to an extent, for a dissociative of the PCP class that is.

I used to love diving into a k hole and blasting Tricky's album "Pre Millenium Tension." Ah, those were the days. Here are some lyrics from that album:

"I heard the phone ring, should I answer?
This is getting serious as terminal cancer.
And that is the final stage.
My primal rage begin to rise, and I started to fantasize.

"How many many more?
I tried to rush the door.
The night before, my finger trigger was sore...that didn't phase me.
What could I say?
I was having a fucked up day."

So, to answer the question again, you just have to recrystallize the powder. I just don't know with what solvent or solvent pair.
 
You must log in or register to reply here.
Top