how do u remove benzthonium chloride from ketamine mixtures?

[fastandbulbous]

Also, certain brands (eg Ketaset) seemed intrinsically stronger than others (eg Ketalar). It's too bad the stuff's so darn neurotoxic, though. It made me have dark, violent thoughts.

Ketamine, neurotoxic - non mon cherie! It's not neurotoxic (you don't get Olney's leisons in proimates). OK it doesn't do your chances of joining Mensa any favours, but it's not dure to neurotoxicity, but from squishing LTP in memory formation (all in the hippocampus - the memory's telephone exchange)

People will yell to the hilt about the dangers of 1970's era prescription PCA (para-chloroamphetamine) but ketamine's Ar-Cl is deemed safe. And it is, to an extent, for a dissociative of the PCP class that is.

Para chloroamphetamine is an entirely different beast to ketamine, metabolized differently, different enzymes, different receptor targets etc. Anyway ketamine is ortho-chlorophenyl not para and last time I checked , ortho substitutoin in amphetamines isn't dodgy (I thenk there was a benzphetamine derivative that contained an ortho - chloro group)

 

[fizzacyst]

I've always wondered why 100mg ketamine/mL in one 10 mL bottle boils down to 1.2g powder after drying under convection. I've always figured that extra 0.2g was benzethonium chloride--an invert (N+) soap--but who knows?
...

All of the vials of pharmaceutical ketamine I've had (many!) have had the dosages listed in terms of actual ketamine (as if it were the base) at 100mg/mL, but provide the HCl salt since the freebase is obviously not going to be water soluble, which is actually about 115mg/mL... so that is 1.15g per 10mL. How accurate is your scale, and are you certain you have driven off all the water at time of weighing? Inaccurate scale or 0.05mL leftover water (not very much) could create this 50mg "extra". All of the preparations I've used have had that preservative at 0.9%. That along with scale error of maybe 20mg or so (are you calibrating it and using a hood, or at least in very still air?) could easily give you that reading. I suspect it is just your scale accuracy and/or precision.

 

[<pyridinyl_30>]

It was my precision. I was only massing to one decimal point. That and people always told me it came out to 1.2g.