How did the coke affect my friend longer........

[SoCalXtC]

Hey just got a G of coke last night and am wondering how it affected my friend for a lot longer than me. We both did about the same amount.... actully my friend did prob. a little more than me. He has more experience with snorting Coke. We both snorted about 5 good sized lines each @ about 11:45. When we got back to my friends house @ about 12:50, I had stopped feeling the effects but my friend was still goin, talking my ear off. He still seemed to be high off his ass untill about 3:30am, and I must say my friend has more experience with coke than me. Kinda sucked cause he was talking my ass off the whole night and I was tired as hell. Just wondering why he was able to be fukked up so much longer than me tonight...

 

[SoCalXtC]

I mean I did more than him... my bad sorrry

 

[pinger]

Different metabolism, different diet, different physical attributes, different age, different upbringing, different value sets, diffent experiences, different minds, different receptors, different genes.

 

[ChaCha]

pinger's hit the nail on the head. It has nothing to with "experience", it just different body chemistry.

 

[The_Bean]

He had some more hidden and was still using.
The_Bean

 

[PhreeX]

^^^ This sounds like the most likely answer
Some people might just REALLY have a weird reaction to cocaine, another idea is that the coke wore off but he kinda tricked himself into thinking he was still wired, I mean, I am sure he was still high on his energy but the cocaine had probably left him by then...

 

[Ayrios]

Didn't I read something here the other day about some class of pharmaceuticals he could have been on prolong the effects of cocaine by half an hour or so?

 

[quale]

Cocaine is metabolized by CYP3A4. It has been shown to be inhibited by ergotomine, medzolam, erythomycin . That last one is pretty cool, not to difficult to get your hands on. I imagine these would lengthen the high.
Also there is variation amoung individuals in the expression of these various enzymes. This may be the case here.

 

[fairnymph]

Is your friend taking Wellbutrin or Effexor? Both of these antidepressants are known to prolong the cocaine high.
Also, if your friend has bipolar, that might explain it as well; many bipolar people have atypical reactions to drugs, which often involve the drug being stronger and/or lasting longer.

 

[Dr Deceptikon]

11:45 to 3:30!?! Your friend had a backup stash!

 

[PhreeX]

I never found any of the crap about Wellbutrin to be justified (never tried Effexor) .. I still maintain, this guy must have had extra or else he tricked himself into thinking he had something he didn't!