I'm currently going through a pretty rough comedown after taking about 500mg one night, and about 150mg the second night, of some of the purest mdma i've ever had, on wednesday and thursday. I always make a point to take no more than 250mg, and that will royally mess me up. The comedown is manageable though, with breaks of 3 months in between sessions. So what i've learned from this experience is to never take more than your optimal dose, which shouldn't exceed 250mg absolute max. Never take more than 3 bombs in one night as this only means you end up trying to desperately make it last longer when you start to comedown - pointless. And never take mdma 2 nights in a row - won't even come up the second night and it will only make the following days harder to deal with.